Publications of U. Reichl

Genzel, Y.; Dietzsch, C.; Rapp, E.; Schwarzer, J.; Reichl, U.: MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation. Applied Microbiology and Biotechnology 88 (2), pp. 461 - 475 (2010)

Heynisch, B.; Frensing, T.; Heinze, K.; Seitz, C.; Genzel, Y.; Reichl, U.: Differential activation of host cell signaling pathways through infection with two variants of influenza A /Puerto Rico /8/34 (H1N1) in MDCK cells. Vaccine 28 (51), pp. 8210 - 8218 (2010)

Janke, R.; Genzel, Y.; Freund, S.; Wolff, M. W.; Grammel, H.; Rühmkorf, C.; Seidemann, J.; Wahl, A.; Reichl, U.: Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cells. Journal of Biotechnology 150 (3), pp. 396 - 403 (2010)

Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Measurement of Key Metabolic Enzyme Activities in Mammalian Cells Using Rapid and Sensitive Microplate-Based Assays. Biotechnology and Bioengineering 107 (3), pp. 566 - 581 (2010)

Kröber, T.; Knöchlein, A.; Eisold, K.; Kalbfuß-Zimmermann, B.; Reichl, U.: DNA Depletion by Precipitation in the Purification of Cell Culture-Derived Influenza Vaccines. Chemical Engineering and Technology 33 (6), pp. 941 - 959 (2010)

Lohr, V.; Genzel, Y.; Behrendt, I.; Scharfenberg, K.; Reichl, U.: A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor. Vaccine 28 (38), pp. 6256 - 6264 (2010)

Öncül, A.; Kalmbach, A.; Genzel, Y.; Reichl, U.; Thevenin, D.: Characterization of flow conditions in 2 L and 20 L wave bioreactors using Computational Fluid Dynamics. Biotechnology Progress 26 (1), pp. 101 - 110 (2010)

Ritter, J.; Wahl, A.; Freund, S.; Genzel, Y.; Reichl, U.: Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling. BMC Systems Biology 4, 61 (2010)

Rollié, S.; Lendeckel, U.; Naumann, M.; Reichl, U.; Sundmacher, K.: Dynamics of bionanoparticle targeting in mixtures of human tumour cells by validated population balance modelling. Soft Matter 6 (6), pp. 1203 - 1216 (2010)

Seitz, C.; Frensing, T.; Höper, D.; Kochs, G.; Reichl, U.: High yields of Influenza A virus in MDCK cells are promoted by an insufficient IFN-induced antiviral state. Journal of General Virology 91 (7), pp. 1754 - 1763 (2010)

Vester, D.; Pflugmacher, A.; Hoffmann, D.; Seitz, C.; Heldt, S.; Bettenbrock, K.; Genzel, Y.; Reichl, U.: Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamics. Journal of Virological Methods 168 (1-2), pp. 63 - 71 (2010)

Vester, D.; Rapp, E.; Kluge, S.; Genzel, Y.; Reichl, U.: Virus-host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approach. Journal of Proteomics 73 (9), pp. 1656 - 1669 (2010)

Wolff, M.; Siewert, C.; Hansen, S. P.; Faber, R.; Reichl, U.: Purification of cell culture-derived modified Vaccinia Ankara virus by pseudo-affinity membrane adsorbers and hydrophobic interaction chromatography. Biotechnology and Bioengineering 107 (2), pp. 312 - 320 (2010)

Wolff, M.; Siewert, C.; Lehmann, S.; Hansen, S.P.; Djurup, R.; Faber, R.; Reichl, U.: Capturing of Cell Culture-Derived Modified Vaccinia Ankara Virus by Ion Exchange and Pseudo-Affinity Membrane Adsorbers. Biotechnology and Bioengineering 105 (4), pp. 761 - 769 (2010)

Bock, A.; Möhler, L.; Sann, H.; Schulze-Horsel, J.; Genzel, Y.; Reichl, U.: Growth behaviour of number distributed adherent MDCK cells for optimization in large scale microcarrier cultures. Biotechnology Progress 25 (6), pp. 1717 - 1731 (2009)

Genzel, Y.; Reichl, U.: Continuous cell lines as production system for influenza vaccines. Expert Review of Vaccines 8 (12), pp. 1681 - 1692 (2009)

Lohr, V.; Rath, A.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation. Vaccine 27 (36), pp. 4975 - 4982 (2009)

Opitz, L.; Hohlweg, J.; Reichl, U.; Wolff, M. W.: Purification of cell culture-derived influenza virus A/Puerto Rico/8/34 by membrane-based immobilized metal affinity chromatography. Journal of Virological Methods 161 (2), pp. 312 - 316 (2009)

Opitz, L.; Lehmann, S.; Reichl, U.; Wolff, M. W.: Sulfated membrane adsorbers for economic pseudo-affinity capture of influenza virus particles. Biotechnology and Bioengineering 103 (6), pp. 1144 - 1154 (2009)

Rapp, E.; Charvat, A.; Beinsen, A.; Plessmann, U.; Reichl, U.; Seidel-Morgenstern, A.; Urlaub, H.; Abel, B.: Atmospheric Pressure Free Liquid Infrared MALDI Mass Spectrometry: Toward a combined ESI/MALDI-Liquid Chromatography Interface. Analytical Chemistry 81 (1), pp. 443 - 452 (2009)