Publications of Sven Göbel

Fernandes, R. P.; Göbel, S.; Reiter, M.; Bryan, A.; Altomonte, J.; Genzel, Y.; Peixoto, C.: Streamlining the purification of a clinical-grade oncolytic virus for therapeutic applications. Separation and Purification Technology 354, 128769 (2025)

Göbel, S.; Kazemi, O.; Ma, J.; Jordan, I.; Sandig, V.; Paulissen, J.; Kerstens, W.; Thibaut, H. J.; Reichl, U.; Dallmeier, K. et al.; Genzel, Y.: Parallel Multifactorial Process Optimization and Intensification for High-Yield Production of Live YF17D-Vectored Zika Vaccine. Vaccines 12 (7), 755 (2024)

Göbel, S.; Pelz, L.; Silva, C. A. T.; Brühlmann, B.; Hill, C.; Altomonte, J.; Kamen, A.; Reichl, U.; Genzel, Y.: Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration. Applied Microbiology and Biotechnology 108 (1), 240 (2024)

Göbel, S.; Jaén, K. E.; Dorn, M.; Neumeyer, V.; Jordan, I.; Sandig, V.; Reichl, U.; Altomonte, J.; Genzel, Y.: Process intensification strategies toward cell culture‐based high‐yield production of a fusogenic oncolytic virus. Biotechnology and Bioengineering 120 (9), pp. 2639 - 2657 (2023)

Göbel, S.; Jaén, K. E.; Fernandes, R. P.; Reiter, M.; Altomonte, J.; Reichl, U.; Genzel, Y.: Characterization of a quail suspension cell line for production of a fusogenic oncolytic virus. Biotechnology and Bioengineering 120, pp. 3335 - 3346 (2023)

Göbel, S.; Kortum, F.; Chavez, K. J.; Jordan, I.; Sandig, V.; Reichl, U.; Altomonte, J.; Genzel, Y.: Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures. Applied Microbiology and Biotechnology 106, pp. 4945 - 4961 (2022)

Gränicher, G.; Babakhani, M.; Göbel, S.; Jordan, I.; Marichal-Gallardo, P.; Genzel, Y.; Reichl, U.: A high cell density perfusion process for Modified Vaccinia virus Ankara production: process integration with inline DNA digestion and cost analysis. Biotechnology and Bioengineering 118 (12), pp. 4720 - 4734 (2021)

Göbel, S.; Pelz, L.; Reichl, U.; Genzel, Y.: Upstream processing for viral vaccines - Process intensification. In: Bioprocessing of Viral Vaccines, pp. 137 - 174 (Eds. Kamen, A.; Cervera, L.). CRC Press, Boca Raton (2023)

Pelz, L.; Göbel, S.; Jaen , K.; Reichl, U.; Genzel, Y.: Upstream processing for viral vaccines – General aspects. In: Bioprocessing of Viral Vaccines, pp. 79 - 136 (Eds. Kamen , A.; Cervera , L.). CRC Press, Boca Raton (2023)

Göbel, S.; Dorn, M.; Jaén Chavez, K.; Jordan, I.; Sandig, V.; Altomonte, J.; Genzel, Y.; Reichl, U.: Production of a fusogenic oncolytic rVSV-NDV virus in perfusion processes. In Proceedings Vaccine Technology VIII, 60. Vaccine Technology VIII, Sitges (Spain), June 12, 2022 - June 17, 2022. (2022)

Göbel, S.; Pelz, L.; Behrendt, I.; Prömmel, M.; Altomonte, J.; Anderlei, T.; Bürgin, T.; Genzel, Y.; Reichl, U.: Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus production. In Proceedings Single-Use Technologies V: Building the Future, 40. Single-Use Technologies V: Building the Future, Marseille, France, March 20, 2022 - March 23, 2022. (2022)

Genzel, Y.; Göbel, S.; Reichl, U.: Shaking to very high cell densities - perfusion for virus production. Kuhner Large Scale Meeting, Girona (Spain) (2024)

Genzel, Y.; Zinnecker, T. M.; Göbel, S.; Reichl, U.: Next-generation virus production: from clone, to AMBR, to perfusion and very high virus yield. 8th Edition of the "International Symposium on Immunobiologicals" (8th ISI), Rio de Janeiro (Brazil) (2024)

Genzel, Y.; Zinnecker, T. M.; Göbel, S.; Reichl, U.: Intensified cell-based virus production: A process development challenge for multiple cell-virus combinations. 16^th PEACe Conference, Sitges (Spain) (2023)

Genzel, Y.; Zinnecker, T. M.; Göbel, S.; Reichl, U.: Next-Generation Virus Production: From Clone, to AMBR, to Perfusion and Very High Virus Yield. International Society for Vaccines (ISV) Annual Congress, Lausanne (Switzerland) (2023)

Genzel, Y.; Zinnecker, T. M.; Göbel, S.; Reichl, U.: Increase in supply through use of new technologies for high yield vaccines. Flanders Vaccine, Brussels (Belgium) (2023)

Göbel, S.; Dallmeier, K.; Jordan, I.; de Jong, J.; Reichl, U.; Genzel, Y.: Intensified production for a yellow fever - ZIKA virus vaccine candicate. Democratization of biotherapies: new manufacturing modalities and intensification's, Oxford, UK (2023)

Göbel, S.; Jaén, K. E.; Pelz, L.; Reiter , M.; Altomonte, J.; Reichl, U.; Genzel, Y.: Intensifiying OSB processes for high titer virus production. 5^th large scale meeting: Orbital shaken bioreactors, Girona (Spain) (2023)

Göbel, S.; Pelz, L.; Behrendt, I.; Prömmel, M.; Altomonte, J.; Anderlei, T.; Bürgin, T.; Genzel, Y.; Reichl, U.: Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus production. Single-Use Technologies V: Building the Future, Marseille, France (2022)

Gränicher, G.; Göbel, S.; Marichal-Gallardo, P.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: Integrated cell-culture based MVA virus production process with perfusion mode for vaccines or gene therapy. Value through intensified bioprocessing II, Oxford, United Kingdom (2022)