Reaction network analysis and kinetics

Hydroaminomethylation of long chain olefins

Kinetics of reductive amination and hydroaminomethylation in reactive multiphase fluid systems

Figure 1: Scheme for the coupling of hydroformylation and reductive amination from renewable feedstocks to the desired products. — **Figure 1:** Scheme for the coupling of hydroformylation and reductive amination from renewable feedstocks to the desired products.

**Figure 1:** Scheme for the coupling of hydroformylation and reductive amination from renewable feedstocks to the desired products.

The Collaborative Research Center Transregio 63 of the German Research Foundation (DFG) develops methods and strategies to adapt established reactions to substrates from renewable raw materials, as illustrated in Figure 1. In the first two funding periods, the reaction network for the hydroformylation of long-chain olefins (1-dodecene, 1-decene) was identified, the catalytic cycles for all main and side reactions were developed and mechanistic kinetic models were derived. Focus of the third funding period is the evaluation of the potential of complex homogeneously catalyzed tandem reactions using the example of the rhodium-catalyzed hydroaminomethylation (HAM) which couples the hydroformylation with the reductive amination (RA). Thus, the gained knowledge and developed methods for the hydroformylation (HYFO) should be used to analyse and quantify the kinetics for the overall reaction system of the hydroaminomethylation.

References

Gerlach M., Kirschtowski S., Jameel F., Huxoll F., Stein M., Sadowski G., Seidel-Morgenstern A., & Hamel C. (2021). Kinetic Modeling of Complex Catalytic Reactions in Multiphase Systems, Chapter in the book written by the InPROMT consortium: Integrated Chemical Processes in Liquid Multiphase systems - From chemical reaction to process design and operation (Ed. Kraume M.), De Gruyter, Oldenbourg, to be submitted in 2021.

Kirschtowski, S., Jameel, F., Stein, M., Seidel-Morgenstern, A., & Hamel, C. (2021). Kinetics of the Reductive Amination of 1-Undecanal in Thermomorphic Multicomponent System. Chemical Engineering Science, 116187.

Kirschtowski, S., Kadar, C., Seidel-Morgenstern, A., & Hamel, C. (2020). Kinetic Modeling of Rhodium-Catalyzed Reductive Amination of Undecanal in Different Solvent Systems. Chemie-Ingenieur-Technik, 92(5), 582-588.

Gerlach, M., Kirschtowski, S., Seidel-Morgenstern, A., & Hamel, C. (2018). Kinetic Modeling of the Palladium-Catalyzed Isomerizing Methoxycarbonylation of 1-Decene. Chemie-Ingenieur-Technik, 90(5), 673-678.