Influenza Virus Vaccine Production in disposable bioreactors

Research report (imported) 2007 - Max Planck Institute for Dynamics of Complex Technical Systems

Genzel, Yvonne; Reichl, Udo
Discussion on preparedness for a possible influenza pandemic is still ongoing. Authorities and public interest have now accelerated the development of alternative production systems to the classical egg-based production. New disposable bioreactors have been evaluated in the upstream processing group using different analytical tools comparing the influenza virus production with two different mammalian cells. These bioreactors show a potential for fast and simple up-scaling of production capacities in case of a pandemic.

For the full text, see the German version.

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