Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone:+49 391 6110-200Fax:+49 391 6110-203

Group Page

Publications

Publications BPE group

Conference Paper (33)

  1. 251.
    Bock, A.; Reichl, U.: Closed loop control of perfusion systems in high-density cell culture. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 549 - 551 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  2. 252.
    Genzel, Y.; Fischer, M.; Olmer, R. M.; Schäfer, B.; Best, C.; König, S.; Hundt, B.; Reichl, U.: Serum-free influenza vaccine production with MDCK cells in wave-bioreactor and 5L-stirred tank bioreactor. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 563 - 565 (Ed. Smith, R.). 19th ESACT Meeting , Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  3. 253.
    Genzel, Y.; Schulze-Horsel, J.; Möhler, L.; Sidorenko, Y.; Reichl, U.: Influenza Vaccines: Challenges in Mammalian Cell Culture Technology. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 503 - 508 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  4. 254.
    Hundt, B.; Straube, S.; Schlawin, N.; Kaßner, H.; Reichl, U.: Cultivation of E-FL in Perfusion Mode Using Wave Bioreactor and Stirre-Tank Reactor for Parvovirus Vaccine Production. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 519 - 522 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  5. 255.
    Pohlscheidt, M.; Langer, U.; Bödeker, B.; Paulsen, D.; Rübsamen-Waigmann, H.; Reichl, U.; Henzler, H. J.; Apeler, H.: Strategies for Large Scale Production of Parapoxvirus Ovis NZ-2. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 707 - 710 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - August 06, 2005. Springer, Dordrecht, The Netherlands (2007)
  6. 256.
    Reichl, U.: Biological Fundamentals, Models and Technologies for Vaccine Production. In: Perspectives of Research - Identification and Implementation of Research Topics by Organizations: Ringberg-Symposium Mai 2006, Vol. 7, pp. 191 - 208. Ringberg-Symposium, Kreuth, Germany, May 03, 2006 - May 05, 2006. (2007)
  7. 257.
    Schulze-Horsel, J.; Genzel, Y.; Reichl, U.: Monitoring of Cell Physiology in Influenza Vaccine Production by Flow Cytometry. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 531 - 533 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - August 06, 2005. Springer, Dordrecht, The Netherlands (2007)
  8. 258.
    Genzel, Y.; Alt, R.; Reichl, U.: Glutamine-free media for vaccine production processes. In: Animal Cell Technology meets Genomics: Proceedings ot the 18th ESACT Meeting, pp. 767 - 770 (Eds. Godia, F.; Fussenegger, M.). 18th ESACT Meeting , Granada, Spain, May 11, 2003 - May 14, 2003. (2005)
  9. 259.
    Hundt, B.; Schänzler, A.; Reichl, U.: Serum free cultivation of primary chicken embryo fibroblasts in microcarrier systems for vaccine production. In: Animal Cell Technology Meets Genomics: Proceedings of the 18th ESACT Meeting, pp. 771 - 774. 18th ESACT Meeting, Granada, Spain, May 11, 2003 - May 14, 2003. (2005)
  10. 260.
    Reichl, U.; Genzel, Y.; Möhler, L.; Sidorenko, Y.; Sann, H.: Animal cell cultures for the production of viral vaccines. In: GVC/DECHEMA Vortrags- und Diskussiontagung "Zellkulturen: vom biologischen System zum Produktionsprozess", pp. 32 - 35. GVC/DECHEMA : Vortrags- und Diskussionstagung, Bad Dürkheim, Deutschland, May 26, 2003 - May 28, 2003. (2003)
  11. 261.
    Genzel, Y.; Voges, L.; Reichl, U.: Development of bioprocess concepts on vaccine production: influenza virus as an example. In: Animal cell technology: from target to market, pp. 344 - 346 (Eds. Lindner-Olsson, E.; Chatzissavidou, N.; Luellau, E.). 17th ESACT Meeting, Tylösand, Sweden, June 10, 2001 - June 14, 2001. (2001)

Meeting Abstract (44)

  1. 262.
    Bissinger, T.; Reichl, U.; Genzel, Y.; Wu, Y.; Liu, X.; Tan, W.-S.: Highly efficient influenza virus production: A MDCK-based high-cell-density process. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  2. 263.
    Coronel, J.; Genzel, Y.; Reichl, U.; Behrendt, I.; Buergin, T.; Andereli, T.; Sandig, V.: Orbital shaken bioreactor for influenza A virus production in high cell density cultivations. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  3. 264.
    Fortuna, A. R.; Taft, F.; Villain, L.; Wolff, M. W.; Reichl, U.: Continuous purification of cell culture-derived influenza A virus particles through pseudo- affinity membrane chromatography. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  4. 265.
    Gränicher, G.; Genzel, Y.; Reichl, U.; John, K.; Sandig, V.; Karlas, A.: A new porcine suspension cell line (PBG.PK-21) provides efficient production for influenza and yellow fever vaccine viruses. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  5. 266.
    Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: Single-cell analysis uncovers a novel influenza A virus-derived defective interfering particle for antiviral therapy. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  6. 267.
    Marichal-Gallardo, P.; Fortuna, A. R.; Genzel, Y.; Wolff, M. W.; Reichl, U.: Purifying viruses with a sheet of paper: Single-use steric exclusion chromatography as a capture platform for vaccine candidates. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  7. 268.
    Nikolay, A.; Genzel, Y.; Schwamborn, K.; Leon, A.; Reichl, U.: Flavivirus production in perfusion processes using the EB66® cell line. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  8. 269.
    Peixoto, C.; Carvalho, S. B.; Carrondo, M. J.T.; Alves , P. M.; Fortuna, A. R.; Reichl, U.; Wolff, M. W.: Addressing the challenges of influenza virus-like particles purification. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  9. 270.
    Taft, F.; Köhler, R.; Van Teeffelen, S.; Fortuna, A. R.; Wolff, M. W.; Reichl, U.; Villain, L.; Boulais, A.: Influenza virus capture using membrane chromatography: Improving selectivity by matrix design and pseudo-affinity ligand interactions. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  10. 271.
    Wu, Y.; Liu, X.; Tan, W.-S.; Bissinger, T.; Genzel, Y.; Reichl, U.: Efficient influenza vaccine manufacturing: Single MDCK suspension cells in chemically defined medium. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  11. 272.
    Tapia, F.; Genzel, Y.; Reichl, U.; Sandig, V.: Stirred tanks in cascades and plug-flow tubular bioreactors for continuous production of viral vaccines. In: ECI Symposium Series. Integrated Continuous Biomanufacturing III, Cascais, Portugal, September 17, 2017 - September 21, 2017. (2017)
  12. 273.
    Pieler, M.; Frentzel, S.; Bruder , D.; Wolff, M. W.; Reichl, U.: Pseudo-affinity purification and formulation of a cell-culture derived whole influenza virus vaccine using magnetic sulfated cellulose particles. In: Vaccine Technology VI. Vaccine Technology VI, Albufeira, Portugal, June 12, 2016 - June 17, 2016. (2016)
  13. 274.
    Alagesan, K.; Campbell, M.; Hennig, R.; Hoffmann, M.; Reichl, U.; Seeberger, P. H.; Packer, N. H.; Rapp, E.; Kolarich, D.: IgCarbKB: a glycomics and glycoproteomics focused immunoglobulin knowledge base. In: Glycoconjugate Journal, Vol. 32, p. 321 - 321. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  14. 275.
    Cajic, S.; Müller, C.; Hennig, R.; Hoffmann, D.; Schambach, A.; Reichl, U.; Buettner, F. F. R.; Rapp, E.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. In: Glycoconjugate Journal, Vol. 32, p. 206 - 206. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  15. 276.
    Hennig, R.; Tuchscherer, J.; Smalla, K.-H.; Herrera-Molina, R.; Naumann, M.; Reichl, U.; Kähne, T.; Rapp, E.: The Sweet Side of Neurons–xCGE-LIF Based Structural Characterization of Neuron and Synaptic N-GlycansComposition. In: Glycoconjugate Journal, Vol. 32, p. 293 - 293. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  16. 277.
    Hoffmann, M.; Marx, K.; Wuhrer, M.; Reichl, U.; Rapp, E.: Human blood plasma O-glycoproteomics. In: Glycoconjugate Journal, pp. 324 - 325. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  17. 278.
    Stavenhagen, K.; Schirmeister, F.; Baumgart, D. C.; Hennig, R.; Rapp, E.; Reichl, U.; Seeberger, P. H.: Region-specific N-glycan mapping in inflammatory bowel disease and control tissue using PGC-LC-ESI-MS/MS. In: Glycoconjugate Journal, Vol. 32, p. 290 - 290. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  18. 279.
    Fernandes, P.; Castro, R.; Laske, T.; Genzel, Y.; Kremer, E.; Alves, P.; Coroadinha, A.: The impact of MDCK cell source on the production of influenza and canine adenovirus. In: New Biotechnology: Abstracts of the 16th European Congress on Biotechnology, Vol. 31 Supplement, p. S180. (2014)
  19. 280.
    Müller, C.; Hoffmann, D.; Cajic, S.; Hennig, R.; Sgodda, M.; van Diepen, L.; Weissmann, R.; Steinemann, D.; Rapp, E.; Kuss, A. et al.; Cantz, T.; Schambach, A.; Büttner, F.: Functional characterization of PMM2-CDG patient-derived iPSCs. In: GLYCOBIOLOGY, p. 1101 - 1101. (2014)
  20. 281.
    Müller, C.; Hoffmann, D.; Cajic, S.; Hennig, R.; Sgodda, M.; van Diepen, L.; Weissmann, R.; Steinemann, D.; Rapp, E.; Kuss, A. et al.; Cantz, T.; Schambach, A.; Buettner, F.: Functional characterization of PMM2-CDG patient-derived iPSCs. In: Glycobiology, Vol. 24, p. 1101 - 1101. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, Hawaii, USA, November 16, 2014 - November 19, 2014. IRL Press at Oxford University Press, Oxford (2014)
  21. 282.
    Müller, C.; Hoffmann, D.; Cajic, S.; Hennig, R.; Sgodda, M.; van Diepen, L.; Weissmann, R.; Steinemann, D.; Rapp, E.; Kuss, A. et al.; Cantz, T.; Schambach, A.; Buettner, F. F. R.: Molecular characterization of hiPSCs from a PMM2-CDG patient revealed aberrant glycosylation. In: Glycobiology, Vol. 24, pp. 1176 - 1177. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, Hawaii, USA, November 16, 2014 - November 19, 2014. IRL Press at Oxford University Press, Oxford (2014)
  22. 283.
    Pucic-Bakovic, M.; Huffman, J. E.; Klaric, L.; Hennig, R.; Selman, M. H. J.; Aulchenko, Y. S.; Rapp, E.; Wuhrer , M.; Lauc, G.: Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research. In: Glycobiology, Vol. 24, p. 1160 - 1160. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, Hawaii, USA, November 16, 2014 - November 19, 2014. IRL Press at Oxford University Press, Oxford (2014)
  23. 284.
    Barradas, O.P.; Jandt, U.; Phan, L.D.; Villanueva, M.; Rath, A.; Reichl, U.; Schräder, E.; Scholz, S.; Noll, T.; Sandig, V. et al.; Pörtner, R.; Zeng, A.P.: Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell culture. In: BMC Proceedings, Vol. 5. 22nd European Society for Animal Cell Technology (ESACT) - Meeting on Cell Based Technologies , Vienna, Austria, May 15, 2011 - May 18, 2011. (2011)
  24. 285.
    Borowiak, M.; Hennig, R.; Kottler, R.; Reichl, U.; Rapp, E.: Tailored methods for CGE-LIF based multiplexed high-throughput glycoanalysis with respect to sample characteristics. In: Glycoconjugate Journal, Vol. 28, p. 332. 21st International Symposium on Glycoconjugates - Glyco 21, Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  25. 286.
    Hennig, R.; Borowiak, M.; Ruhaak, L. R.; Wuhrer, M.; Rapp, E.: High-Throughput CGE-LIF Based Analysis of APTS-labeled N-Glycans, Utilizing a Multiplex Capillary DNA Sequencer. In: Glycoconjugate Journal, Vol. 28, p. 331. 21st International Symposium on Glycoconjugates (Glyco 21), Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  26. 287.
    Hennig, R.; Reichl, U.; Rapp, E.: A Software Tool for Automated High-Throughput Processing of CGE-LIF Based Glycoanalysis Data, Generated by a Multiplexing Capillary DNA Sequencer. In: Glycoconjugate Journal, Vol. 28, p. 331. 21st International Symposium on Glycoconjugates (Glyco 21), Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  27. 288.
    Hütter, J.; Rödig, J.; Reichl, U.; Seeberger, P. H.; Rapp, E.; Lepenies, B.: Impact of Influenza A virus hemagglutinin N-glycosylation on immunogenicity. In: Glycoconjugate Journal, Vol. 28, p. 305. 21st International Symposium on Glycoconjugates (Glyco 21), Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  28. 289.
    Janke, R.; Genzel, Y.; Wetzel, M.; Reichl, U.: Effect of influenza virus infection on key metabolic enzyme activities in MDCK cells. In: BMC Proceedings, Vol. 5. 22nd European Society for Animal Cell Technology (ESACT) - Meeting on Cell Based Technologies , Vienna, Austria, May 15, 2011 - May 18, 2011. (2011)
  29. 290.
    Kolarich, D.; Rapp, E.; Packer, N.: Bioinformatics in Glycoproteomics – Challenges, Frontiers and Solutions. In: Glycoconjugate Journal, Vol. 28, p. 251. 21st International Symposium on Glycoconjugates (Glyco 21), Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  30. 291.
    Kottler, R.; Hennig, R.; Mank, M.; Stahl, B.; Reichl, U.; Rapp, E.: High-Throughput Characterization of the Human Milk Oligosaccharide Composition Utilizing a Multiplexing Capillary DNA Sequencer. In: Glycoconjugate Journal, Vol. 28, p. 330. 21st International Symposium on Glycoconjugates (Glyco 21), Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  31. 292.
    Rapp, E.; Hennig, R.; Borowiak, M.; Kottler, R.; Reichl, U.: High-Throughput Glycosylation Pattern Analysis of Glycoproteins Utilizing a Multiplexing Capillary-DNA-Sequencer. In: Glycoconjugate Journal, Vol. 28, p. 234. 21st International Symposium on Glycoconjugates - Glyco 21, Wien, Östereich, August 21, 2011 - August 26, 2011. (2011)
  32. 293.
    Roedig, J.; Rapp, E.; Genzel, Y.; Reichl, U.: Impact of different influenza cultivation conditions on HA N-glycosylation. In: BMC Proceedings, Vol. 5. 22nd European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies , Vienna, Austria, May 15, 2011 - May 18, 2011. (2011)
  33. 294.
    Scholz, S.; Luebbecke, M.; Rath, A.; Schraeder, E.; Rose, T.; Büntemeyer, H.; Scheper, T.; Reichl, U.; Noll, T.: Characterization of the human AGE1.HN cell line: a systems biology approach. In: BMC Proceedings, Vol. 5. 22nd European Society for Animal Cell Technology (ESACT) - Meeting on Cell Based Technologies , Vienna, Austria, May 15, 2011 - May 18, 2011. (2011)
  34. 295.
    Schräder, E.; Scholz, S.; Niklas, J.; Rath, A.; Barradas, O.P.; Jandt, U.; Sandig, V.; Rose, T.; Pörtner, R.; Reichl, U. et al.; Zeng, A.P.; Heinzle, E.; Noll, T.: Characterisation of cultivation of the human cell line AGE1.HN.AAT. In: BMC Proceedings, Vol. 5, p. P87. 22nd European Society for Animal Cell Technology (ESACT) - Meeting on Cell Based Technologies , Vienna, Austria, May 15, 2011 - May 18, 2011. (2011)
  35. 296.
    Kuhn, R.; Benndorf, D.; Rapp, E.; Reichl, U.; Pollice, A.; Palese, L.: Metaproteomanalyse von Klärschlamm aus Membranbioreaktoren. In: Chemie Ingenieur Technik, Vol. 82, pp. 1539 - 1540 . Processet-Jahrestagung 2010 und 28. Jahrestagung der Biotechnologen, Aachen, Germany, September 21, 2010 - September 23, 2010. Verlag Chemie, GmbH, Weinheim, Germany (2010)
  36. 297.
    Vester, D.; Rapp, E.; Kluge, S.; Genzel, Y.; Reichl, U.: Virus-Wirtszell-Interaktion bei der Produktion von Influenza A Impfstoff in tierischer Zellkultur: Änderungen des Proteoms von Produktionszelllinien. In: Chemie Ingenieur Technik, Vol. 82, p. 1496. ProcessNet-Jahrestagung 2010 und 28. Jahrestagung der Biotechnologen, Aachen, Germany, September 21, 2010 - September 23, 2010. (2010)
  37. 298.
    Öncül, A.; Kalmbach, A.; Genzel, Y.; Reichl, U.; Thevenin, D.: Numerische und experimentelle Untersuchung der Fließbedingungen in Wave-Bioreaktoren. In: Chemie-Ingenieur-Technik, Vol. 81, p. 1241 . ProcessNet-Jahrestagung 2009 und 27. Jahrestagung der Biotechnologen, Mannheim, Germany, September 08, 2009 - September 10, 2009. Verlag Chemie, GmbH, Weinheim, Germany (2009)
  38. 299.
    Noack, S.; Wahl, A.; Oldiges, M.; Wiechert, W.: Visualizing regulatory interactions in metabolic networks. In: BMC Systems Biology, Vol. 1, p. 5. BioSysBio 2007 : Systems Biology, Bioinformatics and Synthetic Biology, Manchester, UK, January 11, 2007 - January 13, 2007. (2007)
  39. 300.
    Sidorenko, Y.; Dauner, M.; Genzel, Y.; Reichl, U.: Metabolic Flux Analysis of MDCK Cells in Glutamine-Containing and Glutamine-Free Culture Media. In: Metabolic Engineering VI: Program, p. 102. Metabolic Engineering IV, Noordwijkerhout, The Netherlands, October 01, 2006 - October 05, 2006. (2006)
 
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