Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone:+49 391 6110 200Fax:+49 391 6110 203

Group Page

Publications

Publications BPE group

Journal Article (16)

  1. 1.
    Castro, R.; Fernandes, P.; Laske, T.; Sousa, M. F. Q.; Genzel, Y.; Scharfenberg, K.; Alves, P.M.; Coroadinha, A.S.: Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells. Applied Microbiology and Biotechnology 99 (17), pp. 7059 - 7068 (2015)
  2. 2.
    Frensing, T.: Defective interfering viruses and their impact on vaccines and viral vectors. Biotechnology Journal 10 (5), pp. 681 - 689 (2015)
  3. 3.
    Gallo Ramirez, L. E.; Nikolay, A.; Genzel, Y.; Reichl, U.: Bioreactor concepts for cell culture-based viral vaccine production. Expert Review of Vaccines 14 (9), pp. 1181 - 1191 (2015)
  4. 4.
    Genzel, Y.: Designing cell lines for viral vaccine production: Where do we stand? Biotechnology Journal 10 (5), pp. 728 - 740 (2015)
  5. 5.
    Heldt, F. S.; Kupke, S. Y.; Dorl, S.; Frensing, T.; Reichl, U.: Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nature Communications 6, 8938 (2015)
  6. 6.
    Heyer, R.; Kohrs, F.; Reichl, U.; Benndorf, D.: Metaproteomics of complex microbial communities in biogas plants. Microbial Biotechnology 8 (5), pp. 749 - 763 (2015)
  7. 7.
    Karsten, C. B.; Büttner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A.; Sauermann, U.; Reichl, U.; Gerardy-Schahn, R.; Rapp, E. et al.; Stahl-Hennig, C.; Pöhlmann, S.: Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques. Journal of Virology 89 (22), pp. 11727 - 11733 (2015)
  8. 8.
    Kluge, S.; Benndorf, D.; Genzel, Y.; Scharfenberg, K.; Rapp, E.; Reichl, U.: Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension. Vaccine 33 (35), pp. 4269 - 4280 (2015)
  9. 9.
    Kohrs, F.; Wolter, S.; Benndorf, D.; Heyer, R.; Hoffmann, M.; Rapp, E.; Bremges, A.; Sczyrba, A.; Schlüter, A.; Reichl, U.: Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities. Proteomics 15 (20), pp. 3585 - 3589 (2015)
  10. 10.
    Kolmeder , C.; Ritari, J.; Verdam , F.; Muth, T.; Keskitalo, S.; Varjosalo , M.; Fuentes, S.; Greve , J.; Buurman , W.; Reichl, U. et al.; Rapp, E.; Martens, L.; Palva, A.; Salonen, A.; Rensen, S.; de Vos, W.: Colonic metaproteomic signatures of active bacteria and the host in obesity. Proteomics 15 (20), pp. 3544 - 3552 (2015)
  11. 11.
    Muth, T.; Behne, A.; Heyer, R.; Kohrs, F.; Benndorf, D.; Hoffmann, M.; Lehteva, M.; Reichl, U.; Martens, L.; Rapp, E.: The MetaProteomeAnalyzer: A Powerful Open-Source Software Suite for Metaproteomics Data Analysis and Interpretation. Journal of Proteome Research 14 (3), pp. 1557 - 1565 (2015)
  12. 12.
    Muth, T.; Kolmeder, C. A.; Salojärvi, J.; Keskitalo, S.; Varjosalo, M.; Verdam, F. J.; Rensen, S. S.; Reichl, U.; de Vos, W. M.; Rapp, E. et al.; Martens, L.: Navigating through metaproteomics data: A logbook of database searching. Proteomics 15 (20), pp. 3439 - 3453 (2015)
  13. 13.
    Oveland, E.; Muth, T.; Rapp, E.; Martens, L.; Berven, F. S.; Barsnes, H.: Viewing the proteome: How to visualize proteomics data? Proteomics 15 (8), pp. 1341 - 1355 (2015)
  14. 14.
    Püttker, S.; Kohrs, F.; Benndorf, D.; Heyer, R.; Rapp, E.; Reichl, U.: Metaproteomics of activated sludge from a wastewater treatment plant- a pilot study. Proteomics 15 (20), pp. 3596 - 3601 (2015)
  15. 15.
    Serve, A.; Pieler, M.; Benndorf, D.; Rapp, E.; Wolff, M. W.; Reichl, U.: Comparison of Influenza Virus Particle Purification Using Magnetic Sulfated Cellulose Particles with an Established Centrifugation Method for Analytics. Analytical Chemistry 87 (21), pp. 10708 - 10711 (2015)
  16. 16.
    Theuerl, S.; Kohrs, F.; Benndorf, D.; Maus, I.; Wibberg, D.; Schlüter, A.; Kausmann, R.; Heiermann, M.; Rapp, E.; Reichl, U. et al.; Pühler, A.; Klocke, M.: Community shifts in a well-operating agricultural biogas plant: how process variations are handled by the microbiome. Applied Microbiology and Biotechnology 99 (18), pp. 7791 - 7803 (2015)

Book item (2)

  1. 17.
    Hennig, R.; Rapp, E.; Kottler, R.; Cajic, S.; Reichl, U.: N -Glycosylation Fingerprinting of Viral Glycoproteins by xCGE-LIF. In: Carbohydrate-Based Vaccines: Methods and Protocols, pp. 123 - 143. Springer, New York (2015)
  2. 18.
    Kalbfuß, B.; Reichl, U.: Viral Vaccines Purification. In: Vaccine Development and Manufacturing, pp. 97 - 181. John Wiley & Sons, Hobroken, New Jersey (2015)

Conference Paper (1)

  1. 19.
    Kramer, B.; Tüngler, R.; Bettenbrock, K.; Conradi, C.: A compact mathematical model of mandelate racemase production and chaperone overexpression in E. coli. 8th Vienna Interantional Conference on Mathematical Modelling , Vienna, Austria, February 18, 2015 - February 20, 2015. IFAC-PapersOnLine 48 (1), pp. 23 - 28 (2015)

Meeting Abstract (5)

  1. 20.
    Alagesan, K.; Campbell, M.; Hennig, R.; Hoffmann, M.; Reichl, U.; Seeberger, P. H.; Packer, N. H.; Rapp, E.; Kolarich, D.: IgCarbKB: a glycomics and glycoproteomics focused immunoglobulin knowledge base. In: Glycoconjugate Journal, Vol. 32, p. 321 - 321. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  2. 21.
    Cajic, S.; Müller, C.; Hennig, R.; Hoffmann, D.; Schambach, A.; Reichl, U.; Buettner, F. F. R.; Rapp, E.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. In: Glycoconjugate Journal, Vol. 32, p. 206 - 206. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  3. 22.
    Hennig, R.; Tuchscherer, J.; Smalla, K.-H.; Herrera-Molina, R.; Naumann, M.; Reichl, U.; Kähne, T.; Rapp, E.: The Sweet Side of Neurons–xCGE-LIF Based Structural Characterization of Neuron and Synaptic N-GlycansComposition. In: Glycoconjugate Journal, Vol. 32, p. 293 - 293. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  4. 23.
    Hoffmann, M.; Marx, K.; Wuhrer, M.; Reichl, U.; Rapp, E.: Human blood plasma O-glycoproteomics. In: Glycoconjugate Journal, pp. 324 - 325. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  5. 24.
    Stavenhagen, K.; Schirmeister, F.; Baumgart, D. C.; Hennig, R.; Rapp, E.; Reichl, U.; Seeberger, P. H.: Region-specific N-glycan mapping in inflammatory bowel disease and control tissue using PGC-LC-ESI-MS/MS. In: Glycoconjugate Journal, Vol. 32, p. 290 - 290. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)

Event talk (162)

  1. 25.
    Wang, W.; Voigt, A.; Wolff, M. W.; Reichl, U.; Sundmacher, K.: Optimization of affinity membrane adsorption by evaluating multivalent interaction. ECCE10+ECAB3+EPIC5 , Nice, France (2015)
  2. 26.
    Benndorf, D.; Kohrs, F.; Heyer, R.; Rapp, E.; De Vrieze, J.; Boon, N.; Schlüter, A.; Sczyrba, A.; Reichl, U.: An optimized workflow for high-throughput metaproteomics of biogas plants. 9th International Symposium on Anaerobic Microbiology, Portorož, Slovenia (2015)
  3. 27.
    Cajic, S.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Croatia (2015)
  4. 28.
    Cajic, S.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. Hannover Medical School-Institute for Cellular Chemistry, Hannover (2015)
  5. 29.
    Frensing, T.: Single-cell analysis and stochastic modeling reveal large cell-to-cell variability in the cell culture-based production of influenza A virus. ESACT 2015, Barcelona, Spain (2015)
  6. 30.
    Benndorf, D.: Metaproteomics of complex microbial communities in biogas plants. Biogas Seminar, Norwegian University of Life Sciences, Ås campus, Norwegen (2015)
  7. 31.
    Frensing, T.: Impact of virus-host cell interactions on cell culture-based influenza vaccine production. Protein Expression in Animal Cells (PEACE) Conference, USA, San Diego (2015)
  8. 32.
    Genzel, Y.: Animal cell culture-based viral vaccine production. The Sixth International School on Production of Biologicals using Animal Cell Cultures, Rio de Janairo (2015)
  9. 33.
    Genzel, Y.: Deciding on cultivation vessel & process strategy for cell culture-based viral vaccine production. The Sixth International School on Production of Biologicals using Animal Cell Cultures, Rio de Janairo (2015)
  10. 34.
    Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the dynamics of influenza A virus replication in the presence of defective interfering RNAs. 2nd Workshop on Virus Dynamics, Toronto, Ontario, Canada (2015)
  11. 35.
    Kröber, T.; Wolff, M.; Hundt, B.; Reichl, U.; Seidel-Morgenstern, A.: Purification of Cell Culture-Derived Influenza Virus using Continuous Simulated Moving Bed Chromatography. ISPPP 2011, Alexandria, USA (2015)
  12. 36.
    Genzel, Y.; Schulze-Horsel, J.; Möhler, L.; Sidorenko, Y.; Reichl, U.: Influenza Vaccines: Challenges in Mammalian Cell Culture Technology. 19th ESACT Meeting, Harrogate, UK (2015)
  13. 37.
    Genzel, Y.; Reichl, U.: Metabolism as a key for improvement of cell culture processes-status and advances in analytics and data analysis. 23rd ESACT Meeting, Lille, France (2015)
  14. 38.
    Lohr, V.; Rath, A.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: Avian designer cells AGE1.CR: possible candidates for MVA and influenza vaccine production? 21st ESACT Meeting, Dublin, Ireland (2015)
  15. 39.
    Reichl, U.: Options & challenges in modeling metabolism. 23rd ESACT Meeting, Lille, France (2015)
  16. 40.
    Balck, A.; Michalzik, M.; Wolff, M. W.; Reichl, U.; Büttgenbache, S.: Influenza Virus Detection in Vaccine Production with a Quartz Crystal Microbalance. Biosensors 2008, Shanghai, China (2015)
  17. 41.
    Benndorf, D.; Heyer, R.; Kohrs, F.; Hanreich, A.; Klocke, M.; Rapp, E.; Reichl, U.: Gel-free metaproteome analysis of a biogas reactor. 1st International Conference on Biogas Microbiology, Leipzig, Germany (2015)
  18. 42.
    Benndorf, D.; Kuhn, R.; Kohrs, F.; Palese, L. L.; Pollice, A.; Hanreich, A.; Heyer, R.; Klocke, M.; Rapp, E.; Reichl, U.: Metaproteome analysis in environmental biotechnology. First international symposium on microbial resource management in biotechnology: concepts & applications, Genth, Belgium (2015)
  19. 43.
    Bensmann, B.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Sundmacher, K.: Methanation of renewable hydrogen within biogas reactors? A process systems engineering approac. CHISA 2014, Prague/Czech Republic (2015)
  20. 44.
    Dietzsch, C.; Genzel, Y.; Reichl, U.: Vero or MDCK cells for influenza A virus production in microcarrier systems? European BioPerspectives 2007, Cologne, Germany (2015)
  21. 45.
    Frensing, T.; Seitz, C.; Heynisch, B.; Reichl, U.: Influence of Host Cell Defence during Influenza Vaccine Production in MDCK Cells. Vaccine Technology III, Puerto Vallarta, Mexiko (2015)
  22. 46.
    Genzel, Y.; Vogel, T.; Buck, J.; Behrendt, I.; Schiedner, G.; Jordan, I.; Reichl, U.: High cell density cultivations for influenza virus production using suspension cells. Vaccine Technology IV, Albufeira, Portugal (2015)
  23. 47.
    Genzel, Y.; Lohr, V.; Behrendt, I.; Scharfenberg, K.; Kamen, A.; Schiedner, G.; Jordan, I.; Reichl, U.: Cell culture-based influenza virus production: suspension or adherent producer cell lines? Cell line development and engineering 2012, Cologne, Germany (2015)
  24. 48.
    Genzel, Y.; Reichl, U.: Evaluation of a new cell line for vaccine production. Fourth International School on Production of Biologicals in Animal Cell Cultures, Rio de Janeiro, Brazil (2015)
  25. 49.
    Genzel, Y.; Reichl, U.: Vaccine production in animal cell cultures. Fourth International School on Production of Biologicals in Animal Cell Cultures, Rio de Janeiro, Brazil (2015)
  26. 50.
    Genzel, Y.; Janke, R.; Isken, B.; Rödig, J.; Rapp, E.; Lohr, V.; Behrendt, I.; Scharfenberg, K.; Kamen, A.; Schiedner, G. et al.; Jordan, I.; Reichl, U.: Influenza virus production: characteristics of different producer cell lines. 10th PEACe 2011, Cascais, Portugal (2015)
 
Go to Editor View
loading content