Analysis and Redesign of Biological Networks
In collaborations with experimental partners we study realistic cellular systems in an iterative cycle of wet and dry lab investigations. Application examples include the data-driven elucidation of signaling network topologies or the rational (re)design of bacterial metabolic networks towards bio-based production of certain chemicals. The group also has an experimental research team studying specific aspects of metabolic regulation and metabolic engineering in the model bacterium E. coli.
Overall, a long-term vision of the ARB group is to help pave the way for routine use of mathematical modeling and network analysis in biology, biotechnology, and biomedicine.
A detailed description of our research activities can be found here.
Keywords: Systems Biology, Computational Biology, Bioinformatics, Metabolic Engineering, Signal Transduction Networks, Metabolic Networks, Gene Regulatory Networks, Escherichia coli