Head of the Group

Dr.-Ing. Steffen Klamt
Dr.-Ing. Steffen Klamt
Phone: +49 391 6110 480
Fax: +49 391 6110 509

Secretary

Anke Goettert
Phone: +49 391 6110 477
Fax: +49 391 6110 452

News

11.05.2017: New Publication         
Zander D, Samaga, R, Straube R, Bettenbrock K. (2017) Bistability and Nonmonotonic Induction of the lac Operon in the Natural Lactose Uptake System. Biophysical Journal 112: 1984-1996.

09.05.2017: New Publication         
Klamt S, Regensburger G, Gerstl MP, Jungreuthmayer C, Schuster S, Mahadevan R, Zanghellini J, Müller S. (2017) From elementary flux modes to elementary flux vectors: Metabolic pathway analysis
with arbitrary linear flux constraints. PLoS Comput Biol 13: e1005409.

24.02.2017: New Publication         
Prigent S, Frioux C, Dittami SM, Thiele S,.....(2017) Meneco, a Topology-Based Gap-Filling Tool Applicable to Degraded Genome-Wide Metabolic Networks PLoS Comput Biol 13: e1005276.

10.01.2017: News     
We have open PhD and Postdoc positions in our group.

10.01.2017: New Publication        
Hädicke O, Klamt S (2017) EColiCore2: a reference model of the central metabolism of Escherichia coli and the relationships to its genome-scale parent model. Scientific Reports 7: 39647.

Open Postitions

Doctoral students (PhD) in Mathematics / Computational Biology / Computer Science

A doctoral position in mathematics / computational biology / computer science and related areas is available in Steffen Klamt’s group at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg (Germany). Our group develops and applies methods and algorithms for the mathematical modeling and targeted modification of biological networks. One particular focus is the application of computational and model-driven approaches for the rational metabolic engineering of microorganisms to optimize biotechnological processes.

 

For a larger research project, which is funded by the European Research Council (ERC) and combines innovative computational and experimental techniques to establish a new design principle for engineering microbial cell factories, we are looking for a talented doctoral student willing to work in an interdisciplinary team. The candidate should have an excellent degree or/and experience in one or several of the following fields:

 

  • Mathematics / Biomathematics
  • Informatics / Bioinformatics / Computational biology
  • Systems biology / Metabolic engineering
  • Physics

 

Experiences in the following areas are of particular advantage (but no explicit requirement):

- mathematical modeling of metabolic networks (e.g., kinetic or constraint-based modeling), computational  strain design, model-based metabolic engineering

- theory and algorithms of mathematical optimization; in particular, linear and mixed-integer linear programming (LP / MILP)

- programming in MATLAB; experience with CPLEX or/and JAVA

Some basic biological knowledge or/and experiences in working in interdisciplinary projects would be a plus but are not mandatory.

The Max Planck Institute and our group offer excellent research opportunities in a stimulating and friendly environment. Salary and benefits are commensurate with TVöD-Bund. The position is available from May 2017 (later starting date would be possible), initially for two years with the possibility of an extension. The Max Planck Society is committed to increasing the representation of women and persons with physical disabilities. We particularly encourage such individuals to apply.

 

There is no strict deadline and the call is open until the position is filled. Applicants should prepare a single PDF file containing an application letter, CV, certificates, a short statement of research interests, a brief description of scientific achievements (if applicable), and, if possible, contact information for two references. This PDF file should be send to
klamt@mpi-magdeburg.mpg.de as soon as possible.

 

More information on the group can be found on the website http://www.mpi-magdeburg.mpg.de/arb

 
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