Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone:+49 391 6110-200Fax:+49 391 6110-203

Group Page

Publications

Publications BPE group

Journal Article (20)

  1. 1.
    Carvalho, S. B.; Fortuna, A. R.; Wolff, M. W.; Peixoto, C.; Alves, P. M.; Reichl, U.; Carrondo, M. J. T.: Purification of influenza virus-like particles using sulfated cellulose membrane adsorbers. Journal of Chemical Technology and Biotechnology 93 (7), pp. 1988 - 1996 (2018)
  2. 2.
    Clerc, F.; Novokmet, M.; Dotz, V.; Reiding, K. R.; de Haan , N.; Kammeijer, G. S.M.; Dalebout, H.; Bladergroen, M. R.; Vukovic, F.; Rapp, E. et al.; Targan, S. R.; Barron, G.; Manetti , N.; Latiano, A.; McGovern, D. P.B.; Annese, V.; Lauc, G.; Wuhrer, M.: Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases. Gastroenterology 155 (3), pp. 829 - 843 (2018)
  3. 3.
    Fischer, L. M.; Wolff, M. W.; Reichl, U.: Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths. Vaccine 36 (22), pp. 3153 - 3160 (2018)
  4. 4.
    Fischöder, T.; Cajic, S.; Reichl, U.; Rapp, E.; Elling , L.: Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGE-LIF based high-throughput analysis. Biotechnology Journal, e1800305 (2018)
  5. 5.
    Fortuna, A. R.; Taft, F.; Villain, L.; Wolff, M. W.; Reichl, U.: Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers. Engineering in Life Sciences 18 (1), pp. 29 - 39 (2018)
  6. 6.
    Hoffmann, M.; Pioch, M.; Pralow, A.; Hennig, R.; Kottler, R.; Reichl, U.; Rapp, E.: The Fine Art of Destruction: A Guide to In-Depth Glycoproteomic Analyses – Exploiting the Diagnostic Potential of Fragment Ions. Proteomics, e1800282 (accepted)
  7. 7.
    Mahour, R.; Klapproth, J.; Rexer, T.; Schildbach, A.; Klamt, S.; Pietzsch, M.; Rapp, E.; Reichl, U.: Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine. Journal of Biotechnology 283, pp. 120 - 129 (2018)
  8. 8.
    Möginger, U.; Grunewald, S.; Hennig, R.; Kuo, C.-W.; Schirmeister, F.; Voth, H.; Rapp, E.; Khoo, K.-H.; Seeberger, P. H.; Simon, J. C. et al.; Kolarich, D.: Alterations of the Human Skin N- and O-Glycome in Basal Cell Carcinoma and Squamous Cell Carcinoma. Frontiers in Oncology 8 (70) (2018)
  9. 9.
    Munoz, R.I.; Kaehne, T.; Herrera, H.; Rodriguez, S.; Guerra, M.M.; Vio , K.; Hennig, R.; Rapp, E.; Rodriguez, E.: The subcommissural organ and the Reissner fiber: old friends revisited. Cell and Tissue Research (accepted)
  10. 10.
    Muth, T.; Kohrs, F.; Heyer, R.; Benndorf, D.; Rapp, E.; Reichl, U.; Martens, L.; Renard, B. Y.: MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go. Analytical Chemistry 90, pp. 685 - 689 (2018)
  11. 11.
    Nikolay, A.; Léon, A.; Schwamborn, K.; Genzel, Y.; Reichl, U.: Process intensification of EB66 ® cell cultivations leads to high-yield yellow fever and Zika virus production. Applied Microbiology and Biotechnology 102 (20), pp. 8725 - 8737 (2018)
  12. 12.
    Nikolay, A.; Casthilho, L. R.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells. Vaccine 36 (28), pp. 3140 - 3145 (2018)
  13. 13.
    Pioch, M.; Hoffmann, M.; Pralow, A.; Reichl, U.; Rapp, E.: GlyXtoolMS: An Open-Source Pipeline for Semiautomated Analysis of Glycopeptide Mass Spectrometry Data. Analytical Chemistry 90 (20), pp. 11908 - 11916 (2018)
  14. 14.
    Reiding, K.R.; Bondt, A.; Hennig, R.; Gardner, R.A.; O'Flaherty, R.; Trbojević-Akmačić, I.; Shubhakar, A.; Hazes, J.; Reichl, U.; Fernandes, D.L. et al.; Pucic-Bakovic, M.; Rapp, E.; Spencer, D.I.R.; Dolhain, R.; Rudd, P.; Lauc, G.; Wuhrer, M.: High-throughput serum N-glycomics: method comparison and application to study rheumatoid arthritis and pregnancy-associated changes. Molecular and Cellular Proteomics (accepted)
  15. 15.
    Rexer, T.; Schildbach, A.; Klapproth, J.; Schierhorn, A.; Mahour, R.; Pietzsch, M.; Rapp, E.; Reichl, U.: One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides. Biotechnology and Bioengineering 115 (1), pp. 192 - 205 (2018)
  16. 16.
    Rey-Jurado, E.; Tapia, F.; Muñoz-Durango, N.; Lay, M.K.; Carreño, L. J.; Riedel, C. A.; Bueno, S. M.; Genzel, Y.; Kalergis, A. M.: Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution. Frontiers in immunology 9, 26 (2018)
  17. 17.
    Vazquez-Ramirez, D.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: High-cell-density cultivations to increase MVA virus production. Vaccine 36 (22), pp. 3124 - 3133 (2018)
  18. 18.
    Vodovnik, M.; Vrabec, K.; Hellwig, P.; Benndorf, D.; Sezun, M.; Gregori, A.; Gottumukkala, L. D.; Anderson, R. C.; Reichl, U.: Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus. Journal of Cleaner Production 197 (Part 1), pp. 253 - 263 (2018)
  19. 19.
    Wasik, M.; Eichwald, L.; Genzel, Y.; Reichl, U.: Cell culture-based production of defective interfering particles for influenza antiviral therapy. Applied Microbiology and Biotechnology 102 (3), pp. 1167 - 1177 (2018)
  20. 20.
    Wenzel, L.; Heyer, R.; Schallert, K.; Löser, L.; Wünschiers, R.; Reichl, U.; Benndorf, D.: SDS-PAGE fractionation to increase metaproteomic insight into the taxonomic and functional composition of microbial communities for biogas plant samples. Engineering in Life Sciences 18 (7), pp. 498 - 509 (2018)

Conference Paper (2)

  1. 21.
    Duvigneau, S.; Dürr, R.; Laske, T.; Bachmann, M.; Dostert, M.; Reichl, U.; Kienle, A.: Mathematical modeling as a tool to improve influenza vaccine production processes. FOSBE 2018, Chicago, Illinois, USA, August 05, 2018 - August 08, 2018. IFAC-PapersOnLine 51, pp. 1 - 4 (2018)
  2. 22.
    Rüdiger, D.; Kupke, S. Y.; Reichl, U.: A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures. IFAC-PapersOnLine 51, pp. 32 - 33 (2018)

Meeting Abstract (10)

  1. 23.
    Bissinger, T.; Reichl, U.; Genzel, Y.; Wu, Y.; Liu, X.; Tan, W.-S.: Highly efficient influenza virus production: A MDCK-based high-cell-density process. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  2. 24.
    Coronel, J.; Genzel, Y.; Reichl, U.; Behrendt, I.; Buergin, T.; Andereli, T.; Sandig, V.: Orbital shaken bioreactor for influenza A virus production in high cell density cultivations. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  3. 25.
    Fortuna, A. R.; Taft, F.; Villain, L.; Wolff, M. W.; Reichl, U.: Continuous purification of cell culture-derived influenza A virus particles through pseudo- affinity membrane chromatography. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  4. 26.
    Gränicher, G.; Genzel, Y.; Reichl, U.; John, K.; Sandig, V.; Karlas, A.: A new porcine suspension cell line (PBG.PK-21) provides efficient production for influenza and yellow fever vaccine viruses. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  5. 27.
    Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: Single-cell analysis uncovers a novel influenza A virus-derived defective interfering particle for antiviral therapy. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  6. 28.
    Marichal-Gallardo, P.; Fortuna, A. R.; Genzel, Y.; Wolff, M. W.; Reichl, U.: Purifying viruses with a sheet of paper: Single-use steric exclusion chromatography as a capture platform for vaccine candidates. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  7. 29.
    Nikolay, A.; Genzel, Y.; Schwamborn, K.; Leon, A.; Reichl, U.: Flavivirus production in perfusion processes using the EB66® cell line. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  8. 30.
    Peixoto, C.; Carvalho, S. B.; Carrondo, M. J.T.; Alves , P. M.; Fortuna, A. R.; Reichl, U.; Wolff, M. W.: Addressing the challenges of influenza virus-like particles purification. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  9. 31.
    Taft, F.; Köhler, R.; Van Teeffelen, S.; Fortuna, A. R.; Wolff, M. W.; Reichl, U.; Villain, L.; Boulais, A.: Influenza virus capture using membrane chromatography: Improving selectivity by matrix design and pseudo-affinity ligand interactions. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  10. 32.
    Wu, Y.; Liu, X.; Tan, W.-S.; Bissinger, T.; Genzel, Y.; Reichl, U.: Efficient influenza vaccine manufacturing: Single MDCK suspension cells in chemically defined medium. In: Vaccine Technology VII. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Thesis - Diploma (1)

  1. 33.
    Lucas, B.: Untersuchung zum Einfluss des Probenzustandes und der Probenbehandlung auf den HbA1e-Messwert bei der Verwendung der POC Analysengeräte Quo-Lab und Quo-Test. Diploma, 115 pp., Otto-von-Guericke Universität, Magdeburg (2018)

Thesis - Master (5)

  1. 34.
    Cvijetinovic, S.: Development of a Cascade of Immobilized Enzymes for Production of Activated Sugar. Master, 62 pp., KTH Stockholm, Stockholm, Sweden (2018)
  2. 35.
    Bartels, E.: Establishment of qPCR methods for the analysis of recombinant CHO DG44 cells by miRNA, mRNA and gene copy number quantification. Master, 87 pp., Otto-von-Guericke Universität, Magdeburg (2018)
  3. 36.
    Rödel, P.: Long-term propagation of influenza A virus and defective interfering viral paricles dS1(1). Master, 119 pp., Otto-von-Guericke-Universität, Magdeburg (2018)
  4. 37.
    Becher, B.: Einfluss des Prozessierungsstatus von Emtagenomdaten auf die Identifizierung von Proteinen mittels Massenspektrometrie. Master, 53 pp., Otto-von-Guericke Universität, Magdeburg (2018)
  5. 38.
    Stettin, J.: Development of four sandwich ELISAs for monitoring process optimization for a cell culture-based tetravalent vaccine. Master, 74 pp., Otto-von-Guericke-Universität, Magdeburg (2018)

Thesis - Bachelor (3)

  1. 39.
    Lüter, C.: Biogas-Anlagen Simulation mit Aspen. Bachelor, 65 pp., Otto-von-Guericke-Universität, Magdeburg (2018)
  2. 40.
    Buß, E.: Abhängigkeit der Auflösung der Metaproteomanalyse von dem Typ des Massenspektrometers und der Messmethode. Bachelor, 64 pp., Otto-von-Guericke-Universität, Magdeburg (2018)
  3. 41.
    Spohr, N.: Untersuchung des biologischen Abbaus von Phosphonaten mittels Proteomanalyse. Bachelor, 52 pp., Otto-von-Guericke-Universität, Magdeburg (2018)

Editorial (1)

  1. 42.
    Palomares, L. A.; Mukhopadhyay, T. K.; Genzel, Y.; Lua, L. H.L.; Cox, M. M.J.: Vaccine Technology VI: Innovative and integrated approaches in vaccine development. Vaccine 36 (22), pp. 3061 - 3063 (2018)
 
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