Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone:+49 391 6110 200Fax:+49 391 6110 203

Group Page

Publications

Publications BPE group

Journal Article (213)

  1. 1.
    Carvalho, S. B.; Fortuna, A. R.; Wolff, M. W.; Peixoto, C.; Alves, P. M.; Reichl, U.; Carrondo, M. J. T.: Purification of influenza virus-like particles using sulfated cellulose membrane adsorbers. Journal of Chemical Technology and Biotechnology 93 (7), pp. 1988 - 1996 (2018)
  2. 2.
    Clerc, F.; Novokmet, M.; Dotz, V.; Reiding, K. R.; de Haan , N.; Kammeijer, G. S.M.; Dalebout, H.; Bladergroen, M. R.; Vukovic, F.; Rapp, E. et al.; Targan, S. R.; Barron, G.; Manetti , N.; Latiano, A.; McGovern, D. P.B.; Annese, V.; Lauc, G.; Wuhrer, M.: Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases. Gastroenterology 155 (3), pp. 829 - 843 (2018)
  3. 3.
    Fischer, L. M.; Wolff, M. W.; Reichl, U.: Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths. Vaccine 36 (22), pp. 3153 - 3160 (2018)
  4. 4.
    Fischöder, T.; Cajic, S.; Reichl, U.; Rapp, E.; Elling , L.: Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGE-LIF based high-throughput analysis. Biotechnology Journal, e1800305 (2018)
  5. 5.
    Fortuna, A. R.; Taft, F.; Villain, L.; Wolff, M. W.; Reichl, U.: Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers. Engineering in Life Sciences 18 (1), pp. 29 - 39 (2018)
  6. 6.
    Mahour, R.; Klapproth, J.; Rexer, T.; Schildbach, A.; Klamt, S.; Pietzsch, M.; Rapp, E.; Reichl, U.: Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine. Journal of Biotechnology 283, pp. 120 - 129 (2018)
  7. 7.
    Muth, T.; Kohrs, F.; Heyer, R.; Benndorf, D.; Rapp, E.; Reichl, U.; Martens, L.; Renard, B. Y.: MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go. Analytical Chemistry 90, pp. 685 - 689 (2018)
  8. 8.
    Möginger, U.; Grunewald, S.; Hennig, R.; Kuo, C.-W.; Schirmeister, F.; Voth, H.; Rapp, E.; Khoo, K.-H.; Seeberger, P. H.; Simon, J. C. et al.; Kolarich, D.: Alterations of the Human Skin N- and O-Glycome in Basal Cell Carcinoma and Squamous Cell Carcinoma. Frontiers in Oncology 8 (70) (2018)
  9. 9.
    Nikolay, A.; Casthilho, L. R.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells. Vaccine 36 (28), pp. 3140 - 3145 (2018)
  10. 10.
    Nikolay, A.; Léon, A.; Schwamborn, K.; Genzel, Y.; Reichl, U.: Process intensification of EB66 ® cell cultivations leads to high-yield yellow fever and Zika virus production. Applied Microbiology and Biotechnology 102 (20), pp. 8725 - 8737 (2018)
  11. 11.
    Rexer, T.; Schildbach, A.; Klapproth, J.; Schierhorn, A.; Mahour, R.; Pietzsch, M.; Rapp, E.; Reichl, U.: One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides. Biotechnology and Bioengineering 115 (1), pp. 192 - 205 (2018)
  12. 12.
    Rey-Jurado, E.; Tapia, F.; Muñoz-Durango, N.; Lay, M.K.; Carreño, L. J.; Riedel, C. A.; Bueno, S. M.; Genzel, Y.; Kalergis, A. M.: Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution. Frontiers in immunology 9, 26 (2018)
  13. 13.
    Vazquez-Ramirez, D.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: High-cell-density cultivations to increase MVA virus production. Vaccine 36 (22), pp. 3124 - 3133 (2018)
  14. 14.
    Vodovnik, M.; Vrabec, K.; Hellwig, P.; Benndorf, D.; Sezun, M.; Gregori, A.; Gottumukkala, L. D.; Anderson, R. C.; Reichl, U.: Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus. Journal of Cleaner Production 197 (Part 1), pp. 253 - 263 (2018)
  15. 15.
    Wasik, M.; Eichwald, L.; Genzel, Y.; Reichl, U.: Cell culture-based production of defective interfering particles for influenza antiviral therapy. Applied Microbiology and Biotechnology 102 (3), pp. 1167 - 1177 (2018)
  16. 16.
    Wenzel, L.; Heyer, R.; Schallert, K.; Löser, L.; Wünschiers, R.; Reichl, U.; Benndorf, D.: SDS-PAGE fractionation to increase metaproteomic insight into the taxonomic and functional composition of microbial communities for biogas plant samples. Engineering in Life Sciences 18 (7), pp. 498 - 509 (2018)
  17. 17.
    Abeln, M.; Borst, K. M.; Cajic, S.; Thiesler, H.; Kats, E.; Albers, I.; Kuhn, M.; Kaever, V.; Rapp, E.; Münster-Kühnel, A. et al.; Weinhold, B.: Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro. ChemBioChem 18 (13), pp. 1305 - 1306 (2017)
  18. 18.
    Heyer, R.; Schallert, K.; Zoun, R.; Becher, B.; Saake, G.; Benndorf, D.: Challenges and perspectives of metaproteomic data analysis. Journal of Biotechnology 261, pp. 24 - 36 (2017)
  19. 19.
    Hämmerling, F.; Pieler, M.; Hennig, R.; Serve, A.; Rapp, E.; Wolff, M. W.; Reichl, U.; Hubbuch, J.: Influence of the production system on the surface properties of influenza A virus particles. Engineering in Life Sciences 17 (10), pp. 1071 - 1077 (2017)
  20. 20.
    Kohrs, F.; Heyer, R.; Bissinger, T.; Kottler, R.; Schallert, K.; Püttker, S.; Behne, A.; Rapp, E.; Benndorf, D.; Reichl, U.: Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition. Anaerobe 46, pp. 56 - 68 (2017)
  21. 21.
    Konze, S. A.; Cajic, S.; Oberbeck, A.; Hennig, R.; Pich, A.; Rapp, E.; Buettner, F. F. R.: Quantitative Assessment of Sialo-Glycoproteins and N-Glycans during Cardiomyogenic Differentiation of Human Induced Pluripotent Stem Cells. ChemBioChem: A European Journal of Chemical Biology 18 (13), pp. 1317 - 1331 (2017)
  22. 22.
    Liu, Y.; McBride, R.; Stoll, M.; Palma, A. S.; Silva, L.; Agravat, S.; Aoki-Kinoshita, K. F.; Campbell, M. P.; Costello, C. E.; Dell, A. et al.; Haslam, S. M.; Karlsson, N. G.; Khoo, K.-H.; Kolarich, D.; Novotny, M. V.; Packer, N. H.; Ranzinger, R.; Rapp, E.; Rudd, P. M.; Struwe, W. B.; Tiemeyer, M.; Wells, L.; York, W. S.; Zaia, J.; Kettner, C.; Paulson, J. C.; Feizi, T.; Smith, D. F.: The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data. Glycobiology 27 (4), pp. 280 - 284 (2017)
  23. 23.
    Marichal-Gallardo, P.; Pieler, M.; Wolff, M. W.; Reichl, U.: Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol. Journal of Chromatography A 1483 (3), pp. 110 - 119 (2017)
  24. 24.
    Pieler, M.; Heyse, A.; Wolff, M. W.; Reichl, U.: Specific ion effects on the particle size distributions of cell culture–derived influenza A virus particles within the Hofmeister series. Engineering in Life Sciences 17 (5), pp. 470 - 478 (2017)
  25. 25.
    Pralow, A.; Hoffmann, M.; Nguyen-Khuong, T.; Rapp, E.; Reichl, U.: Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine. Scientific Reports 7, 11419 (2017)
  26. 26.
    Ricken, B.; Kolvenbach, B. A.; Bergesch, C.; Benndorf, D.; Kroll, K.; Strnad, H.; Vlcek, C.; Adaixo, R.; Hammes, F.; Shahgaldian, P. et al.; Schäffer, A.; Kohler, H.-P. E.; Corvini , P. F.-X.: FMNH2-dependent monooxygenases initiate catabolism of sulfonamides in Microbacterium sp. strain BR1 subsisting on sulfonamide antibiotics. Scientific Reports 7, 15783 (2017)
  27. 27.
    Tapia, F.; Jordan, I.; Genzel, Y.; Reichl, U.: Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems. PLoS One 12 (8), e0182553 (2017)
  28. 28.
    Bachmann, M.; Breitwieser, T.; Lipps, C.; Wirth, D.; Jordan, I.; Reichl, U.; Frensing, T.: Impaired antiviral response of adenovirus-transformed cell lines supports virus replication. Journal of General Virology 97 (2), pp. 293 - 298 (2016)
  29. 29.
    Bensmann, A.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Kausmann, R.; Plöchl, M.; Heiermann, M.; Reichl, U.; Sundmacher, K.: Diagnostic Concept for Dynamically Operated Biogas Production Plants. Renewable Energy 96 (Part A), pp. 479 - 489 (2016)
  30. 30.
    Cammann, C.; Rath, A.; Reichl, U.; Lingel, H.; Brunner-Weintierl, M.; Simeoni, L.; Schraven, B.; Lindquist, J. A.: Early changes in the metabolic profile of activated CD8+ T cells. BMC Biology 17 (1), 28 (2016)
  31. 31.
    Frensing, T.; Kupke, S. Y.; Bachmann, M.; Fritzsche, S.; Gallo Ramirez, L. E.; Reichl, U.: Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells. Applied Microbiology and Biotechnology 100 (16), pp. 7181 - 7192 (2016)
  32. 32.
    Hennig, R.; Cajic, S.; Borowiak, M.; Hoffmann, M.; Kottler, R.; Reichl, U.; Rapp, E.: Towards personalized diagnostics via longitudinal study of the human plasma N-glycome. Biochimica et Biophysica Acta (BBA) - General Subjects 1860 (8), pp. 1728 - 1738 (2016)
  33. 33.
    Heyer, R.; Benndorf, D.; Kohrs, F.; De Vrieze, J.; Boon, N.; Hoffmann, M.; Rapp, E.; Schlüter, A.; Sczyrba, A.; Reichl, U.: Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type. Biotechnology for Biofuels 9 (9), 155 (2016)
  34. 34.
    Hoffmann, M.; Marx, K.; Reichl, U.; Wuhrer, M.; Rapp, E.: Site-specific O-Glycosylation Analysis of Human Blood Plasma Proteins. Molecular and Cellular Proteomics 15 (2), pp. 624 - 641 (2016)
  35. 35.
    Kluge, S.; Genzel, Y.; Laus, K.; Serve, A.; Pflugmacher, A.; Peschel, B.; Rapp, E.; Reichl, U.: Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells. Biotechnology Journal 11 (10), pp. 1332 - 1342 (2016)
  36. 36.
    Koch, S.; Benndorf, D.; Fronk, K.; Reichl, U.; Klamt, S.: Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process. Biotechnology for Biofuels 9, 17 (2016)
  37. 37.
    Laske, T.; Heldt, F. S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 213, pp. 90 - 99 (2016)
  38. 38.
    Laske, T.; Heldt, S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Reprint of “Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 218, pp. 86 - 95 (2016)
  39. 39.
    Meininger, M.; Stepath, M.; Hennig, R.; Cajic, S.; Rapp, E.; Rotering, H.; Wolff, M. W.; Reichl, U.: Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1012-1013, pp. 193 - 203 (2016)
  40. 40.
    Pieler, M.; Frentzel, S.; Bruder , D.; Wolff, M. W.; Reichl, U.: A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection. Vaccine 34 (50), pp. 6367 - 6374 (2016)
  41. 41.
    Rodrigues, A. F.; Guerreiro , M. R.; Formas-Oliveira, A. S.; Fernandes, P.; Blechert, A.-K.; Genzel, Y.; Alves, P.M.; Hu , W.S.; Coroadinha, A.S.: Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK. Biotechnology and Bioengineering 113 (1), pp. 150 - 162 (2016)
  42. 42.
    Salerno, C.; Benndorf, D.; Kluge, S.; Palese, L. L.; Reichl, U.; Pollice, A.: Metaproteomics Applied to Activated Sludge for Industrial Wastewater Treatment Revealed a Dominant Methylotrophic Metabolism of Hyphomicrobium zavarzinii. Microbial Ecology 72 (1), pp. 9 - 13 (2016)
  43. 43.
    Struwe, W.B.; Agravat, S.; Aoki-Kinoshita, K.F.; Campbell, M.P.; Costello, C.E.; Dell, A.; Ten, F.; Haslam, S.M.; Karlsson, N.G.; Khoo, K.H. et al.; Kolarich, D.; Liu, Y.; McBride , R.; Novotny, M.V.; Packer, N.H.; Paulson, J.C.; Rapp, E.; Ranzinger, R.; Rudd, P.M.; Smith, D.F.; Tiemeyer, M.; Wells , L.; York, W.S.; Zaia, J.; Kettner, C.: The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology 26 (9), pp. 907 - 910 (2016)
  44. 44.
    Tanca, A.; Palomba, A.; Fraumene, C.; Pagnozzi, D.; Manghina, V.; Deligios, M.; Muth, T.; Rapp, E.; Martens, L.; Addis, M. F. et al.; Uzzau, S.: The impact of sequence database choice on metaproteomic results in gut microbiota studies. Microbiome 4, 51 (2016)
  45. 45.
    Tapia, F.; Vázquez-Ramirez, D.; Genzel, Y.; Reichl, U.: Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production. Applied Microbiology and Biotechnology 100 (5), pp. 2121 - 2132 (2016)
  46. 46.
    Thiesler, C. T.; Cajic, S.; Hoffmann, D.; Thiel, C.; van Diepen, L.; Hennig, R.; Sgodda, M.; Weißmann, R.; Reichl, U.; Steinemann, D. et al.; Diekmann, U.; Huber, N. M. B.; Oberbeck, A.; Cantz, T.; Kuss, A. W.; Körner, C.; Schambach, A.; Rapp, E.; Buettner, F. F. R.: Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG). Molecular and Cellular Proteomics 15 (4), pp. 1435 - 1452 (2016)
  47. 47.
    Wang, W.; Voigt, A.; Wolff, M. W.; Reichl, U.; Sundmacher, K.: Binding kinetics and multi-bond: Finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces. Analytical Biochemistry 505, pp. 8 - 17 (2016)
  48. 48.
    Weigel, T.; Solomaier, T.; Wehmeyer, S.; Peuker, A.; Wolff, M. W.; Reichl, U.: A membrane-based purification process for cell culture-derived influenza A virus. Journal of Biotechnology 220, pp. 12 - 20 (2016)
  49. 49.
    Castro, R.; Fernandes, P.; Laske, T.; Sousa, M. F. Q.; Genzel, Y.; Scharfenberg, K.; Alves, P.M.; Coroadinha, A.S.: Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells. Applied Microbiology and Biotechnology 99 (17), pp. 7059 - 7068 (2015)
  50. 50.
    Frensing, T.: Defective interfering viruses and their impact on vaccines and viral vectors. Biotechnology Journal 10 (5), pp. 681 - 689 (2015)
 
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