Head of the Group

Dr.-Ing. Steffen Klamt
Dr.-Ing. Steffen Klamt
Phone: +49 391 6110 480
Fax: +49 391 6110 509
Room: S2.10


Susanne Hintsch
Phone:+49 391 6110-477Fax:+49 391 6110-452

News / Latest Publications

28.08.2018: New Publication
Kyselova L, Kreitmayer D, Kremling A & Bettenbrock K (2018) Type and capacity of glucose transport influences succinate yield in two-stage cultivations. Microbial Cell Factories, 17: 132.

10.08.2018: New Publication
Mahour R, Klapproth J, Rexer TFT, Schildbach A, Klamt S, Pietzsch M, Rapp E, Reichl U (2018) Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine. J Biotechnol. 283:120-129.

04.07.2018: Regina defended her PhD thesis.

01.06.2018: New Publication
Bosch J, Klamt S, Stoll M (2018) Generalizing Diffuse Interface Methods on Graphs: Nonsmooth Potentials and Hypergraphs. SIAM J. Appl. Math. 78(3): 1350–1377.

28.04.2018: New Publication
Nitzschke A, Bettenbrock K (2018) All three quinone species play distinct roles in ensuring optimal growth under aerobic and fermentative conditions in E. coli K12. PLoS ONE 13(4): e0194699.


Development of Software: CellNetAnalyzer and ProMoT

Many methods and algorithms developed and used by our group were implemented in our software package CellNetAnalyzer a comprehensive graphical user interface for MATLAB facilitating structural and functional analysis of metabolic and signaling networks [1]. Another software developed at the MPI is the modeling tool ProMoT, which provides a modular modeling concept for the systematic setup of dynamic and logical models [2]. ProMoT is tightly integrated with simulation and analyzing tools including Diana and CellNetAnalyzer. 

References cited above:

  1. Klamt S, Saez-Rodriguez J and Gilles ED (2007) Structural and functional analysis of cellular networks with CellNetAnalyzer. BMC Systems Biology 2:4.
  2. Mirschel, S, Steinmetz K, Rempel R, Ginkel M and Gilles ED (2009) PROMOT: modular modeling for systems biology. Bioinformatics 25:687-689.
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