Systems Biology
Major research interests
Biological systems are inherently complex. Even a simple model organism like the bacterium Escherichia coli is composed of a great number of molecules ranging from simple metabolites to proteins, RNA and DNA. Complex interactions of these molecules take place in order to secure survival and replication and to respond to changing external conditions. Systems Biology aims to a holistic and quantitative understanding of these interactions by combining experimental biological research with mathematical and computational methods.
The main research interests in this context are:
- Analysis of regulatory and metabolic adaptation to aerobic, microaerobic and anaerobic conditions in E. coli
- Developing methods for metabolic engineering of Zymomas mobilis
- Dynamic process control and optimization of biotechnological processes
- Application of electrofermentation in strain and process optimization
