Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203

Contact Person

Annegret Frauendienst
Phone: +49 391 6110 200
Fax: +49 391 6110 203

Group Page


Publications BPE group

Journal Article (194)

  1. 2017
    Abeln, M.; Borst, K. M.; Cajic, S.; Thiesler, H.; Kats, E.; Albers, I.; Kuhn, M.; Kaever, V.; Rapp, E.; Münster-Kühnel, A. et al.; Weinhold, B.: Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro. ChemBioChem: A European Journal of Chemical Biology 18 (13), pp. 1305 - 1306 (2017)
  2. Hämmerling, F.; Pieler, M.; Hennig, R.; Serve, A.; Rapp, E.; Wolff, M. W.; Reichl, U.; Hubbuch, J.: Influence of the production system on the surface properties of influenza A virus particles. Engineering in Life Sciences (accepted)
  3. Kohrs, F.; Heyer, R.; Bissinger, T.; Kottler, R.; Schallert, K.; Püttker, S.; Behne, A.; Rapp, E.; Benndorf, D.; Reichl, U.: Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition. Anaerobe (accepted)
  4. Konze, S. A.; Cajic, S.; Oberbeck, A.; Hennig, R.; Pich, A.; Rapp, E.; Buettner, F. F. R.: Quantitative Assessment of Sialo-Glycoproteins and N-Glycans during Cardiomyogenic Differentiation of Human Induced Pluripotent Stem Cells. ChemBioChem: A European Journal of Chemical Biology 18 (13), pp. 1317 - 1331 (2017)
  5. Liu, Y.; McBride, R.; Stoll, M.; Palma, A. S.; Silva, L.; Agravat, S.; Aoki-Kinoshita, K. F.; Campbell, M. P.; Costello, C. E.; Dell, A. et al.; Haslam, S. M.; Karlsson, N. G.; Khoo, K.-H.; Kolarich, D.; Novotny, M. V.; Packer, N. H.; Ranzinger, R.; Rapp, E.; Rudd, P. M.; Struwe, W. B.; Tiemeyer, M.; Wells, L.; York, W. S.; Zaia, J.; Kettner, C.; Paulson, J. C.; Feizi, T.; Smith, D. F.: The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data. Glycobiology 27 (4), pp. 280 - 284 (2017)
  6. Marichal-Gallardo, P.; Pieler, M.; Wolff, M. W.; Reichl, U.: Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol. Journal of Chromatography A 1483 (3), pp. 110 - 119 (2017)
  7. Nikolay, A.; Casthilho, L. R.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells. Vaccine (accepted)
  8. Pieler, M.; Heyse, A.; Wolff, M. W.; Reichl, U.: Specific ion effects on the particle size distributions of cell culture–derived influenza A virus particles within the Hofmeister series. Engineering in Life Sciences 17 (5), pp. 470 - 478 (2017)
  9. Zmora, P.; Molau-Blazejewska , P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A.; Moldenhauer, A.-S.; Konzok, S.; Dehmel, S.; Sewald, K. et al.; Brinkmann, C.; Curths, C.; Knauf , S.; Gruber, J.; Mätz-Rensing, K.; Dahlmann, F.; Braun, A.; Pöhlmann, S.: Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin. PLoS One 12 (5), e0176597 (2017)
  10. 2016
    Bachmann, M.; Breitwieser, T.; Lipps, C.; Wirth, D.; Jordan, I.; Reichl, U.; Frensing, T.: Impaired antiviral response of adenovirus-transformed cell lines supports virus replication. Journal of General Virology 97 (2), pp. 293 - 298 (2016)
  11. Bensmann, A.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Kausmann, R.; Plöchl, M.; Heiermann, M.; Reichl, U.; Sundmacher, K.: Diagnostic Concept for Dynamically Operated Biogas Production Plants. Renewable Energy 96 (Part A), pp. 479 - 489 (2016)
  12. Cammann, C.; Rath, A.; Reichl, U.; Lingel, H.; Brunner-Weintierl, M.; Simeoni, L.; Schraven, B.; Lindquist, J. A.: Early changes in the metabolic profile of activated CD8+ T cells. BMC Biology 17 (1), 28 (2016)
  13. Frensing, T.; Kupke, S. Y.; Bachmann, M.; Fritzsche, S.; Gallo Ramirez, L. E.; Reichl, U.: Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells. Applied Microbiology and Biotechnology 100 (16), pp. 7181 - 7192 (2016)
  14. Hennig, R.; Cajic, S.; Borowiak, M.; Hoffmann, M.; Kottler, R.; Reichl, U.; Rapp, E.: Towards personalized diagnostics via longitudinal study of the human plasma N-glycome. Biochimica et Biophysica Acta (BBA) - General Subjects 1860 (8), pp. 1728 - 1738 (2016)
  15. Heyer, R.; Benndorf, D.; Kohrs, F.; De Vrieze, J.; Boon, N.; Hoffmann, M.; Rapp, E.; Schlüter, A.; Sczyrba, A.; Reichl, U.: Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type. Biotechnology for Biofuels 9 (9), 155 (2016)
  16. Hoffmann, M.; Marx, K.; Reichl, U.; Wuhrer, M.; Rapp, E.: Site-specific O-Glycosylation Analysis of Human Blood Plasma Proteins. Molecular and Cellular Proteomics 15 (2), pp. 624 - 641 (2016)
  17. Kluge, S.; Genzel, Y.; Laus, K.; Serve, A.; Pflugmacher, A.; Peschel, B.; Rapp, E.; Reichl, U.: Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells. Biotechnology Journal 11 (10), pp. 1332 - 1342 (2016)
  18. Koch, S.; Benndorf, D.; Fronk, K.; Reichl, U.; Klamt, S.: Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process. Biotechnology for Biofuels (9), 17 (2016)
  19. Laske, T.; Heldt, F. S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 213, pp. 90 - 99 (2016)
  20. Laske, T.; Heldt, S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Reprint of “Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 218, pp. 86 - 95 (2016)
  21. Meininger, M.; Stepath, M.; Hennig, R.; Cajic, S.; Rapp, E.; Rotering, H.; Wolff, M. W.; Reichl, U.: Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1012-1013, pp. 193 - 203 (2016)
  22. Pieler, M.; Frentzel, S.; Bruder , D.; Wolff, M. W.; Reichl, U.: A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection. Vaccine 34 (50), pp. 6367 - 6374 (2016)
  23. Rodrigues, A. F.; Guerreiro , M. R.; Formas-Oliveira, A. S.; Fernandes, P.; Blechert, A.-K.; Genzel, Y.; Alves, P.M.; Hu , W.S.; Coroadinha, A.S.: Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK. Biotechnology and Bioengineering 113 (1), pp. 150 - 162 (2016)
  24. Salerno, C.; Benndorf, D.; Kluge, S.; Palese, L. L.; Reichl, U.; Pollice, A.: Metaproteomics Applied to Activated Sludge for Industrial Wastewater Treatment Revealed a Dominant Methylotrophic Metabolism of Hyphomicrobium zavarzinii. Microbial Ecology 72 (1), pp. 9 - 13 (2016)
  25. Struwe, W.B.; Agravat, S.; Aoki-Kinoshita, K.F.; Campbell, M.P.; Costello, C.E.; Dell, A.; Ten, F.; Haslam, S.M.; Karlsson, N.G.; Khoo, K.H. et al.; Kolarich, D.; Liu, Y.; McBride , R.; Novotny, M.V.; Packer, N.H.; Paulson, J.C.; Rapp, E.; Ranzinger, R.; Rudd, P.M.; Smith, D.F.; Tiemeyer, M.; Wells , L.; York, W.S.; Zaia, J.; Kettner, C.: The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology 26 (9), pp. 907 - 910 (2016)
  26. Tanca, A.; Palomba, A.; Fraumene, C.; Pagnozzi, D.; Manghina, V.; Deligios, M.; Muth, T.; Rapp, E.; Martens, L.; Addis, M. F. et al.; Uzzau, S.: The impact of sequence database choice on metaproteomic results in gut microbiota studies. Microbiome 4, 51 (2016)
  27. Tapia, F.; Vázquez-Ramirez, D.; Genzel, Y.; Reichl, U.: Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production. Applied Microbiology and Biotechnology 100 (5), pp. 2121 - 2132 (2016)
  28. Thiesler, C. T.; Cajic, S.; Hoffmann, D.; Thiel, C.; van Diepen, L.; Hennig, R.; Sgodda, M.; Weißmann, R.; Reichl, U.; Steinemann, D. et al.; Diekmann, U.; Huber, N. M. B.; Oberbeck, A.; Cantz, T.; Kuss, A. W.; Körner, C.; Schambach, A.; Rapp, E.; Buettner, F. F. R.: Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG). Molecular and Cellular Proteomics 15 (4), pp. 1435 - 1452 (2016)
  29. Wang, W.; Voigt, A.; Wolff, M. W.; Reichl, U.; Sundmacher, K.: Binding kinetics and multi-bond: Finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces. Analytical Biochemistry 505, pp. 8 - 17 (2016)
  30. Weigel, T.; Solomaier, T.; Wehmeyer, S.; Peuker, A.; Wolff, M. W.; Reichl, U.: A membrane-based purification process for cell culture-derived influenza A virus. Journal of Biotechnology 220, pp. 12 - 20 (2016)
  31. 2015
    Castro, R.; Fernandes, P.; Laske, T.; Sousa, M. F. Q.; Genzel, Y.; Scharfenberg, K.; Alves, P.M.; Coroadinha, A.S.: Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells. Applied Microbiology and Biotechnology 99 (17), pp. 7059 - 7068 (2015)
  32. Frensing, T.: Defective interfering viruses and their impact on vaccines and viral vectors. Biotechnology Journal 10 (5), pp. 681 - 689 (2015)
  33. Gallo Ramirez, L. E.; Nikolay, A.; Genzel, Y.; Reichl, U.: Bioreactor concepts for cell culture-based viral vaccine production. Expert Review of Vaccines 14 (9), pp. 1181 - 1191 (2015)
  34. Genzel, Y.: Designing cell lines for viral vaccine production: Where do we stand? Biotechnology Journal 10 (5), pp. 728 - 740 (2015)
  35. Heldt, F. S.; Kupke, S. Y.; Dorl, S.; Frensing, T.; Reichl, U.: Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nature Communications 6, 8938 (2015)
  36. Heyer, R.; Kohrs, F.; Reichl, U.; Benndorf, D.: Metaproteomics of complex microbial communities in biogas plants. Microbial Biotechnology 8 (5), pp. 749 - 763 (2015)
  37. Karsten, C. B.; Büttner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A.; Sauermann, U.; Reichl, U.; Gerardy-Schahn, R.; Rapp, E. et al.; Stahl-Hennig, C.; Pöhlmann, S.: Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques. Journal of Virology 89 (22), pp. 11727 - 11733 (2015)
  38. Kluge, S.; Benndorf, D.; Genzel, Y.; Scharfenberg, K.; Rapp, E.; Reichl, U.: Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension. Vaccine 33 (35), pp. 4269 - 4280 (2015)
  39. Kohrs, F.; Wolter, S.; Benndorf, D.; Heyer, R.; Hoffmann, M.; Rapp, E.; Bremges, A.; Sczyrba, A.; Schlüter, A.; Reichl, U.: Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities. Proteomics 15 (20), pp. 3585 - 3589 (2015)
  40. Kolmeder , C.; Ritari, J.; Verdam , F.; Muth, T.; Keskitalo, S.; Varjosalo , M.; Fuentes, S.; Greve , J.; Buurman , W.; Reichl, U. et al.; Rapp, E.; Martens, L.; Palva, A.; Salonen, A.; Rensen, S.; de Vos, W.: Colonic metaproteomic signatures of active bacteria and the host in obesity. Proteomics 15 (20), pp. 3544 - 3552 (2015)
  41. Muth, T.; Behne, A.; Heyer, R.; Kohrs, F.; Benndorf, D.; Hoffmann, M.; Lehteva, M.; Reichl, U.; Martens, L.; Rapp, E.: The MetaProteomeAnalyzer: A Powerful Open-Source Software Suite for Metaproteomics Data Analysis and Interpretation. Journal of Proteome Research 14 (3), pp. 1557 - 1565 (2015)
  42. Muth, T.; Kolmeder, C. A.; Salojärvi, J.; Keskitalo, S.; Varjosalo, M.; Verdam, F. J.; Rensen, S. S.; Reichl, U.; de Vos, W. M.; Rapp, E. et al.; Martens, L.: Navigating through metaproteomics data: A logbook of database searching. Proteomics 15 (20), pp. 3439 - 3453 (2015)
  43. Oveland, E.; Muth, T.; Rapp, E.; Martens, L.; Berven, F. S.; Barsnes, H.: Viewing the proteome: How to visualize proteomics data? Proteomics 15 (8), pp. 1341 - 1355 (2015)
  44. Püttker, S.; Kohrs, F.; Benndorf, D.; Heyer, R.; Rapp, E.; Reichl, U.: Metaproteomics of activated sludge from a wastewater treatment plant- a pilot study. Proteomics 15 (20), pp. 3596 - 3601 (2015)
  45. Serve, A.; Pieler, M.; Benndorf, D.; Rapp, E.; Wolff, M. W.; Reichl, U.: Comparison of Influenza Virus Particle Purification Using Magnetic Sulfated Cellulose Particles with an Established Centrifugation Method for Analytics. Analytical Chemistry 87 (21), pp. 10708 - 10711 (2015)
  46. Theuerl, S.; Kohrs, F.; Benndorf, D.; Maus, I.; Wibberg, D.; Schlüter, A.; Kausmann, R.; Heiermann, M.; Rapp, E.; Reichl, U. et al.; Pühler, A.; Klocke, M.: Community shifts in a well-operating agricultural biogas plant: how process variations are handled by the microbiome. Applied Microbiology and Biotechnology 99 (18), pp. 7791 - 7803 (2015)
  47. 2014
    Benndorf, D.; Reichl, U.: Proteomics in environmental and technical microbiology. Engineering in Life Sciences 14 (1), pp. 27 - 46 (2014)
  48. Bensch, G.; Rüger, M.; Wassermann, M.; Weinholz, S.; Reichl, U.; Cordes, C.: Flow cytometric viability assessment of lactic acid bacteria starter cultures produced by fluidized bed drying. Applied Microbiology and Biotechnology 98 (11), pp. 4897 - 4909 (2014)
  49. Bensmann, A.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Reichl, U.; Sundmacher, K.: Biological methanation of hydrogen within biogas plants: A model-based feasibility study. Applied Energy 134, pp. 413 - 425 (2014)
  50. Diba, M.; Goudouri, O.-M.; Tapia, F.; Boccaccini, A. R.: Magnesium-containing bioactive polycrystalline silicate-based ceramics and glass-ceramics for biomedical applications. Current Opinion in solid state & materials science 18 (3), pp. 147 - 167 (2014)
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