Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone: +49 391 6110 200
Fax: +49 391 6110 203
Room: N0.20

Group Page

Publications

Publications BPE group

Talk (233)

  1. 2008
    Balck, A.; Michalzik, M.; Wolff, M. W.; Reichl, U.; Büttgenbache, S.: Influenza Virus Detection in Vaccine Production with a Quartz Crystal Microbalance. Biosensors 2008, Shanghai, China (2008)
  2. Kröber, T.; Lehmann, S.; Solf, N.; Zimmermann, A.; Reichl, U.; Wolff, M. W.: Purification of Hemagglutinin from Host Cell Membranes. ISPPP 2008, Baden-Baden, Germany (2008)
  3. Opitz, L.; Solf, N.; Reichl, U.; Wolff, M. W.: Sulphated cellulose membranes – an economic virus capturing method for influenza virus purification. AIChE Annual meeting and Centennial celebration 2008, Philadelphia, USA (2008)
  4. Rapp, E.: Automated High Throughput Characterization of Carbohydrates and Carbohydrate Mixture Composition Patterns - Utilizing Capillary Gel Electrophoresis with Laser Induced Fluorescence Detection. Meeting with Merck-Serono, Magdeburg, Germany (2008)
  5. Rapp, E.; Charvát, A.; Beinsen, A.; Urlaub, H.; Reichl, U.; Seidel-Morgenstern, A.; Abel, B.: Atmospheric Pressure Free Liquid Infrared Matrix Assisted Laser Dispersion Ionisation: Unifying LC-MS Interfaces. 25th (Montreux) Symosium on Liquid Chromatography / Mass Spectrometry, Montreux, Switzerland (2008)
  6. Rapp, E.; Schwarzer, J.; Reichl, U.: Characterization of the Influenza A Virus Hemagglutinin Glycosylation Pattern with Respect to Vaccine Production - Utilizing Capillary Gel Electrophoresis with Laser Induced Fluorescence Detection. 24th International Carbohydtrate Symposium (ICS), Oslo, Norway (2008)
  7. Rapp, E.: Atmospheric Pressure Free Liquid Infrared MALDI Mass Spectrometry: Towards a unified ESI/MALDI - Liquid Chromatography Interface. MassTech Usermeeting at 56th ASMS, Denver, USA (2008)
  8. Rath, A.; Lohr, V.; Genzel, Y.; Schwarzer, J.; Rapp, E.; Sandig, V.; Jordan, I.; Reichl, U.: Influenza and modified vaccinia Ankara (MVA) production in avian designer cells. Bioperspectives, Hannover, Germany (2008)
  9. Reichl, U.: Increasing Productivity in Influenza Virus Production: Virus Yields in High Cell Density Cultivations. 2008 AIChE Annual Meeting, Philadelphia, USA (2008)
  10. Reichl, U.: A Systems Perspective of Virus Replication in Mammalian Cell Culture. University of Waterloo : Chemical Engineering Seminar, Waterloo, Canada (2008)
  11. Riedele, C.; Schmidt, J. K.; Geisler, L.; Reichl, U.: Antibiotic Pulse Experiments of a 3-species Mixed Culture: Experimental Results and Mathematical Modelling. Analysis of Microbial Cells at the Single Cell Level, Bad Schandau, Germany (2008)
  12. Vester, D.; Genzel, Y.; Gade, D.; Rapp, E.; Reichl, U.: Virus-host cell interactions in a vaccine production process: Proteomic analysis of influenza A virus infected mammalian cells by 2D-DIGE. Proteomics Europe, Lisboa, Portugal (2008)
  13. Wahl, A.; Ritter, J. B.; Genzel, Y.; Reichl, U.: Metabolic flux model for an adherent MDCK cellline: Comparison of flux distributions under different cultivation conditions. Dynamic Systems in Practice Focus : Systems Biology, Magdeburg, Germany (2008)
  14. Wolff, M. W.; Siewert, C.; Lehmann, S.; Opitz, L.; Hansen, S. P.; Djurup, R.; Faber, R.; Reichl, U.: Capturing of cell culture derived Vaccinia Virus by membrane adsorbers. AICHE Annual Meeting, Philadelphia, USA (2008)
  15. Wolff, M. W.; Siewert, C.; Lehmann, S.; Hansen, S. P.; Djurup, R.; Faber, R.; Reichl, U.: Capturing of cell culture derived Vaccinia Virus by heparin-affinity chromatography. European Symposium on Biochemical Engineering 7, Faro, Portugal (2008)
  16. Wolff, M. W.; Venzke, C.; Hansen, S. P.; Djurup, R.; Faber, R.; Reichl, U.: Affinity chromatography of cell culture derived Vaccinia Virus. Vaccine Technology II, Albufeira, Algarve, Portugal (2008)
  17. Öncül, A.; Genzel, Y.; Reichl, U.; Thevenin, D.: Characterization of flow conditions in wave bioreactors using CFD. 7th European Symposium on Biochemical Engineering Science – ESBES-7, Faro, Portugal (2008)
  18. 2007
    Dietzsch, C.; Genzel, Y.; Reichl, U.: Vero or MDCK cells for influenza A virus production in microcarrier systems? European BioPerspectives 2007, Cologne, Germany (2007)
  19. Genzel, Y.; Bock, A.; Schwarzer, J.; Dietzsch, C.; Reichl, U.: Implementation of analytical methods during upstream processing for an influenza A virus production process. Vaccine Production : Analytical Methods, Characterisation, Scale-up and Manufacturing, Cologne, Germany (2007)
  20. Opitz, L.; Zimmermann, A.; Lehmann, S.; Genzel, Y.; Lübben, H.; Reichl, U.; Wolff, M. W.: Efficient influenza virus capture from cell cultivation broth by a novel affinity chromatography. AIChE Annual meeting 2007, Salt Lake City, USA (2007)
  21. Opitz, L.; Zimmermann, A.; Lehmann, S.; Genzel, Y.; Lübben, H.; Reichl, U.; Wolff, M. W.: Novel capturing method for currently spread influenza viruses from cell cultures by affinity separation. ISPPP 2007, Orlando, USA (2007)
  22. Opitz, L.; Zimmermann, A.; Genzel, Y.; Lübben, H.; Reichl, U.; Wolff, M. W.: Lectin-affinity chromatography: a novel purification method for cell culture based Influenza vaccine production from the current season 2006/07. European BioPerspectives 2007, Cologne, Germany (2007)
  23. Opitz, L.; Zimmermann, A.; Genzel, Y.; Lübben, H.; Reichl, U.; Wolff, M. W.: Lektin-Affinitätschromatographie - Neuartige Methode zur Aufreinigung humaner Influenza Viren aus Zellkulturen zur Impfstoffproduktion. DECHEMA/GVC Vortrag- und Diskussionstagung "Aufarbeitung biotechnologischer Produkte", Osnabrück, Germany (2007)
  24. Rapp, E.; Vester, D.; Genzel, Y.; Gade, D.; Reichl, U.: Quantitative proteomic analysis of influenza A virus infected mammalian cells: Elucidation of virus / host cell interactions with respect to the vaccine production process. 27th International Symposium & Exhibit on the Separation of Proteins, Peptides & Polynucleotides (ISPPP 2007), Orlando, USA (2007)
  25. Rapp, E.; Schwarzer, J.; Reichl, U.: Characterisation of Glycosylation Patterns Utilizing a DNA-Sequenzer and Mass Spectrometry. 14th European Carbohydrate Symposium, Lübeck, Germany (2007)
  26. Rapp, E.; Schwarzer, J.; Reichl, U.: Characterisation of Glycosylation Patterns Utilizing a DNA-Sequenzer and a MALDI-TOF Mass Spectrometer. 7th Carbohydrate Bioengineering Meeting (CBM7), Braunschweig, Germany (2007)
  27. Rapp, E.; Schwarzer, J.; Reichl, U.: Elucidation of the Influenza A Virus Glycosylation Patterns with Respect to Vaccine Production Down to the Lower Zeptomolar Range. 21st International Symposium on MicroScale Bioseparations (MSB), Vancouver, BC, Canada (2007)
  28. Reichl, U.: A Systems Perspective of Virus Replication in Mammalian Cell Cultures. Meeting at MPI Golm, Potsdam-Golm, Germany (2007)
  29. Reichl, U.: Influenza Vaccines: Challenges in Optimization of Virus Yields in Mammalian Cell Culture. Vaccine Congress, Amsterdam, The Netherlands (2007)
  30. Reichl, U.: Characterization of Cell Growth and Influenza Virus Replication in Microcarrier Culture. Kooperationsgespräch bei ROCHE AG, Penzberg, Germany (2007)
  31. Reichl, U.: A Systems Perspective of Influenza Virus Replication in Cell Cultures. European Conference on Complex Systems, Dresden, Germany (2007)
  32. Reichl, U.: Theoretical and Experimental Characterization of Influenza Virus Replication in Cell Cultures. Meeting Helmholtz-Zentrum, Braunschweig, Germany (2007)
  33. Reichl, U.: Theoretical and Experimental Characterization of Influenza Virus Replication in Cell Cultures. DECHEMA-Arbeitsausschuss Biotechnologie, Frankfurt/M., Germany (2007)
  34. Reichl, U.: Mathematical Modeling of Mammalian Cell Cultures - Cell Growth and Product Synthesis. MPG-CNRS Treffen, Paris, France (2007)
  35. Reichl, U.: MDCK cell derived influenza vaccines - aspects of up- and downstream processing. Meeting Merck & Co., Inc., USA (2007)
  36. Reichl, U.: Mathematical Modeling of Mammalian Cell Cultures: From Cell Populations to Individual Cells. Workshop "Systems biology", Leipzig, Germany (2007)
  37. Ritter, J. B.; Genzel, Y.; Reichl, U.: Metabolite Analysis in Mammalian Cells: How to generate reliable data sets? 20th ESACT meeting, Dresden, Germany (2007)
  38. Schmidt, J. K.; Riedele, C.; Regestein, L.; Geisler, L.; Reichl, U.: A Medically Relevant Three-Species Mixed Culture in a Chemostat: Mathematical Modelling and Experiments to Study Interaction Effects. European BioPerspectives 2007, Cologne, Germany (2007)
  39. Schwarzer, J.; Rapp, E.; Reichl, U.: N-glycan analysis method for cell culture derived influenza virus hemagglutinin. Joint Meeting 2007, Lille, France (2007)
  40. 2006
    Genzel, Y.; Kalbfuss, B.; Ritter, J. B.; Schulze-Horsel, J.; Rapp, E.; Vester, D.; Reichl, U.: Characterization and analytical issues on an influenza A virus production process. Vaccines : Quality control, scale-up and manufacture, Hamburg, Germany (2006)
  41. Genzel, Y.; Sandig, V.; Jordan, I.: Neue Zellsubstrate und Einfluss von Medien und Prozessführung in der Impfstoffproduktion. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  42. Genzel, Y.; Reichl, U.: Production of vaccines based on animal cell technology. Production of Biopharmaceuticals in Animal Cell Cultures, Rio de Janeiro, Brazil (2006)
  43. Genzel, Y.; Schulze-Horsel, J.; Reichl, U.: High Cell Density Microcarrier Process in a Wave Bioreactor for the Production of Influenza A Virus. Vaccine Technology, Puerto Vallarta, Mexiko (2006)
  44. Genzel, Y.; Reichl, U.: Limits and benefits of the interpretation of extracellular metabolite data in mammalian cell culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
  45. Kalbfuss, B.; Wolff, M. W.; Genzel, Y.; Zimmermann, A.; Morenweiser, R.; Reichl, U.: Chromatography-based purification of influenza A virus for the production of human whole-virion vaccines. ISPPP 2006 : 26th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Innsbruck, Austria (2006)
  46. Kalbfuss, B.; Wolff, M. W.; Geisler, L.; Thom, V.; Reichl, U.: Konzentrierung und Aufreinigung von Influenza Viren mittels Ionenaustauscher-Membranen. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  47. Kalbfuss, B.; Gedicke, K.; Seidel-Morgenstern, A.; Reichl, U.: Maximizing productivity in size-exclusion chromatography of influenza virus: A modelling approach. ESBES 6 : 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (2006)
  48. Kalbfuss, B.; Wolff, M. W.; Genzel, Y.; Zimmermann, A.; Best, C.; Morenweiser, R.; Reichl, U.: A generic purification scheme for the production of human influenza vaccines derived from serum-free mammalian cell culture. Vaccine Technology, Puerto Vallarta, Mexico (2006)
  49. Reichl, U.: MDCK Cell Derived Influenza Vaccines: Aspects of Up- and Downstream Processing. Meeting Academy of Science, Sofia, Bulgarien (2006)
  50. Reichl, U.: Dynamics of Influenza Virus Replication in Mammalian Cell Culture. CCEX Workshop, Vancouver, Canada (2006)
 
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