Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203

Contact Person

Annegret Frauendienst
Phone: +49 391 6110 200
Fax: +49 391 6110 203

Group Page

Publications

Publications BPE group

Journal Article (16)

  1. 2015
    Castro, R.; Fernandes, P.; Laske, T.; Sousa, M. F. Q.; Genzel, Y.; Scharfenberg, K.; Alves, P.M.; Coroadinha, A.S.: Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells. Applied Microbiology and Biotechnology 99 (17), pp. 7059 - 7068 (2015)
  2. Frensing, T.: Defective interfering viruses and their impact on vaccines and viral vectors. Biotechnology Journal 10 (5), pp. 681 - 689 (2015)
  3. Gallo Ramirez, L. E.; Nikolay, A.; Genzel, Y.; Reichl, U.: Bioreactor concepts for cell culture-based viral vaccine production. Expert Review of Vaccines 14 (9), pp. 1181 - 1191 (2015)
  4. Genzel, Y.: Designing cell lines for viral vaccine production: Where do we stand? Biotechnology Journal 10 (5), pp. 728 - 740 (2015)
  5. Heldt, F. S.; Kupke, S. Y.; Dorl, S.; Frensing, T.; Reichl, U.: Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nature Communications 6, 8938 (2015)
  6. Heyer, R.; Kohrs, F.; Reichl, U.; Benndorf, D.: Metaproteomics of complex microbial communities in biogas plants. Microbial Biotechnology 8 (5), pp. 749 - 763 (2015)
  7. Karsten, C. B.; Büttner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A.; Sauermann, U.; Reichl, U.; Gerardy-Schahn, R.; Rapp, E. et al.; Stahl-Hennig, C.; Pöhlmann, S.: Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques. Journal of Virology 89 (22), pp. 11727 - 11733 (2015)
  8. Kluge, S.; Benndorf, D.; Genzel, Y.; Scharfenberg, K.; Rapp, E.; Reichl, U.: Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension. Vaccine 33 (35), pp. 4269 - 4280 (2015)
  9. Kohrs, F.; Wolter, S.; Benndorf, D.; Heyer, R.; Hoffmann, M.; Rapp, E.; Bremges, A.; Sczyrba, A.; Schlüter, A.; Reichl, U.: Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities. Proteomics 15 (20), pp. 3585 - 3589 (2015)
  10. Kolmeder , C.; Ritari, J.; Verdam , F.; Muth, T.; Keskitalo, S.; Varjosalo , M.; Fuentes, S.; Greve , J.; Buurman , W.; Reichl, U. et al.; Rapp, E.; Martens, L.; Palva, A.; Salonen, A.; Rensen, S.; de Vos, W.: Colonic metaproteomic signatures of active bacteria and the host in obesity. Proteomics 15 (20), pp. 3544 - 3552 (2015)
  11. Muth, T.; Behne, A.; Heyer, R.; Kohrs, F.; Benndorf, D.; Hoffmann, M.; Lehteva, M.; Reichl, U.; Martens, L.; Rapp, E.: The MetaProteomeAnalyzer: A Powerful Open-Source Software Suite for Metaproteomics Data Analysis and Interpretation. Journal of Proteome Research 14 (3), pp. 1557 - 1565 (2015)
  12. Muth, T.; Kolmeder, C. A.; Salojärvi, J.; Keskitalo, S.; Varjosalo, M.; Verdam, F. J.; Rensen, S. S.; Reichl, U.; de Vos, W. M.; Rapp, E. et al.; Martens, L.: Navigating through metaproteomics data: A logbook of database searching. Proteomics 15 (20), pp. 3439 - 3453 (2015)
  13. Oveland, E.; Muth, T.; Rapp, E.; Martens, L.; Berven, F. S.; Barsnes, H.: Viewing the proteome: How to visualize proteomics data? Proteomics 15 (8), pp. 1341 - 1355 (2015)
  14. Püttker, S.; Kohrs, F.; Benndorf, D.; Heyer, R.; Rapp, E.; Reichl, U.: Metaproteomics of activated sludge from a wastewater treatment plant- a pilot study. Proteomics 15 (20), pp. 3596 - 3601 (2015)
  15. Serve, A.; Pieler, M.; Benndorf, D.; Rapp, E.; Wolff, M. W.; Reichl, U.: Comparison of Influenza Virus Particle Purification Using Magnetic Sulfated Cellulose Particles with an Established Centrifugation Method for Analytics. Analytical Chemistry 87 (21), pp. 10708 - 10711 (2015)
  16. Theuerl, S.; Kohrs, F.; Benndorf, D.; Maus, I.; Wibberg, D.; Schlüter, A.; Kausmann, R.; Heiermann, M.; Rapp, E.; Reichl, U. et al.; Pühler, A.; Klocke, M.: Community shifts in a well-operating agricultural biogas plant: how process variations are handled by the microbiome. Applied Microbiology and Biotechnology 99 (18), pp. 7791 - 7803 (2015)

Book Chapter (2)

  1. Hennig, R.; Rapp, E.; Kottler, R.; Cajic, S.; Reichl, U.: N -Glycosylation Fingerprinting of Viral Glycoproteins by xCGE-LIF. In: Carbohydrate-Based Vaccines: Methods and Protocols, pp. 123 - 143. Springer, New York (2015)
  2. Kalbfuß, B.; Reichl, U.: Viral Vaccines Purification. In: Vaccine Development and Manufacturing, pp. 97 - 181. John Wiley & Sons, Hobroken, New Jersey (2015)

Conference Paper (1)

  1. Kramer, B.; Tüngler, R.; Bettenbrock, K.; Conradi, C.: A compact mathematical model of mandelate racemase production and chaperone overexpression in E. coli. 8th Vienna Interantional Conference on Mathematical Modelling , Vienna, Austria, February 18, 2015 - February 20, 2015. IFAC-PapersOnLine 48 (1), pp. 23 - 28 (2015)

Meeting Abstract (5)

  1. Alagesan, K.; Campbell, M.; Hennig, R.; Hoffmann, M.; Reichl, U.; Seeberger, P. H.; Packer, N. H.; Rapp, E.; Kolarich, D.: IgCarbKB: a glycomics and glycoproteomics focused immunoglobulin knowledge base. In: Glycoconjugate Journal, Vol. 32, p. 321 - 321. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  2. Cajic, S.; Müller, C.; Hennig, R.; Hoffmann, D.; Schambach, A.; Reichl, U.; Buettner, F. F. R.; Rapp, E.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. In: Glycoconjugate Journal, Vol. 32, p. 206 - 206. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  3. Hennig, R.; Tuchscherer, J.; Smalla, K.-H.; Herrera-Molina, R.; Naumann, M.; Reichl, U.; Kähne, T.; Rapp, E.: The Sweet Side of Neurons–xCGE-LIF Based Structural Characterization of Neuron and Synaptic N-GlycansComposition. In: Glycoconjugate Journal, Vol. 32, p. 293 - 293. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  4. Hoffmann, M.; Marx, K.; Wuhrer, M.; Reichl, U.; Rapp, E.: Human blood plasma O-glycoproteomics. In: Glycoconjugate Journal, pp. 324 - 325. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)
  5. Stavenhagen, K.; Schirmeister, F.; Baumgart, D. C.; Hennig, R.; Rapp, E.; Reichl, U.; Seeberger, P. H.: Region-specific N-glycan mapping in inflammatory bowel disease and control tissue using PGC-LC-ESI-MS/MS. In: Glycoconjugate Journal, Vol. 32, p. 290 - 290. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Kroatien, September 15, 2015 - September 20, 2015. (2015)

Talk (11)

  1. Benndorf, D.: Metaproteomics of complex microbial communities in biogas plants. Biogas Seminar, Norwegian University of Life Sciences, Ås campus, Norwegen (2015)
  2. Benndorf, D.; Kohrs, F.; Heyer, R.; Rapp, E.; De Vrieze, J.; Boon, N.; Schlüter, A.; Sczyrba, A.; Reichl, U.: An optimized workflow for high-throughput metaproteomics of biogas plants. 9th International Symposium on Anaerobic Microbiology, Portorož, Slovenia (2015)
  3. Cajic, S.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. GLYCO 23 XXIII International Symposium on Glycoconjugates, Split, Croatia (2015)
  4. Cajic, S.: Unraveling The N-glycosylation Of Induced Pluripotent Stem Cells From A PMM2-CDG Patient. Hannover Medical School-Institute for Cellular Chemistry, Hannover (2015)
  5. Frensing, T.: Impact of virus-host cell interactions on cell culture-based influenza vaccine production. Protein Expression in Animal Cells (PEACE) Conference, USA, San Diego (2015)
  6. Frensing, T.: Single-cell analysis and stochastic modeling reveal large cell-to-cell variability in the cell culture-based production of influenza A virus. ESACT 2015, Barcelona, Spain (2015)
  7. Genzel, Y.: Animal cell culture-based viral vaccine production. The Sixth International School on Production of Biologicals using Animal Cell Cultures, Rio de Janairo (2015)
  8. Genzel, Y.: Deciding on cultivation vessel & process strategy for cell culture-based viral vaccine production. The Sixth International School on Production of Biologicals using Animal Cell Cultures, Rio de Janairo (2015)
  9. Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the dynamics of influenza A virus replication in the presence of defective interfering RNAs. 2nd Workshop on Virus Dynamics, Toronto, Ontario, Canada (2015)
  10. Muth, T.; Kolmeder, C. A.; Rapp, E.; Reichl, U.; Martens, L.: A closer look into the maze of metaproteomics data. MidWinter Proteomics Bioinformatics Seminar, Semmering, Österreich (2015)
  11. Wang, W.; Voigt, A.; Wolff, M. W.; Reichl, U.; Sundmacher, K.: Optimization of affinity membrane adsorption by evaluating multivalent interaction. ECCE10+ECAB3+EPIC5 , Nice, France (2015)

Poster (13)

  1. Bachmann, M.; Breitwieser, T.; Lipps , C.; Wirth, D.; Jordan, I.; Rose, T.; Sandig, V.; Reichl, U.; Frensing, T.: Impaired antiviral response supports viral vaccine production in adenoviral transformed designer cell lines. 25th Annual Meeting of the Society for Virology, Bochum, Germany (2015)
  2. Bachmann, M.; Breitwieser, T.; Lipps, C.; Wirth, D.; Jordan, I.; Rose, T.; Sandig, V.; Reichl, U.; Frensing, T.: Impaired antiviral response supports influenza vaccine production in adenoviral transformed designer cell lines. ESACT, Barcelona (2015)
  3. Bissinger, T.; Schleuß, T.; Thom, V.; Wolff, M.; Reichl, U.: Separation of Enterovirus 71 Virus Like Particles from Baculovirus by Crossflow Filtration. ESACT 2015, Barcelona, Spain (2015)
  4. Frensing, T.: Single-cell analysis and stochastic modeling reveal large cell-to-cell variability in influenza A virus infection. 16th International Negative Strand Virus Meeting , Siena, Italy (2015)
  5. Heyer, R.; Kohrs, F.; Benndorf, D.; De Vrieze, J.; Rapp, E.; Boon, N.; Reichl, U.: A metaproteomic approach for analysis of microbial community structure and function for improvement of biogas plant performance. 6th Congress of European Microbiologists (FEMS 2015), Maastricht, Netherlands (2015)
  6. Kupke, S. Y.; Heldt, F.S.; Frensing, T.; Reichl, U.: Single Cell Analysis of Influenza A Virus-infected Cells for the Optimization of Cell Culture-based Vaccine Manufacturing Processes. ESACT 2015, Barcelona, Spain (2015)
  7. Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the intracellular replication of influenza A virus in the presence of defective interfering RNAs. International Conference on Systems Biology of Human Disease (SBHD), Heidelberg, Germany (2015)
  8. Muth, T.; Behne, A.; Heyer, R.; Kohrs, F.; Hoffmann, M.; Benndorf, D.; Lehtevä, M.; Reichl, U.; Martens, L.; Rapp, E.: Metaproteomeanalyzer: a software tool for functional and taxonomic characterization of metaproteome data. Konferenz Proteomic Forum, Berlin (2015)
  9. Nikolay, A.; Scharfenberg, K.; Patel, P.; Niedrig, M.; Genzel, Y.; Reichl, U.: Towards yellow fever 17D virus production in Vero suspension cells. ESACT, Barcelona (2015)
  10. Püttker, S.; Kohrs, F.; Benndorf, D.; Heyer, R.; Rapp, E.; Reichl, U.: Analyses of activated sludge metaproteomes of a wastewater treatment plant a metaproteomic data set. 6th Congress of European Microbiologists - FEMS Microbiology Congress 2015, Maastricht, Belgien (2015)
  11. Schildbach, A.; Schomberg, M.; Rapp, E.; Reichl, U.; Pietzsch, M.: In-vitro Synthesis of Lipid-linked (GlcNAc)2-Man by ß-(1,4)-Mannosyltransferase (Alg1) and Activity Assay Based on CGE-LIF Measurements. Cell Biology of Megakaryocytes & Platelets , Lucca (Barga), Italy (2015)
  12. Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Continuous production of viral vaccines with a two-stage bioreactor system. Conference Integrated Continuous Biomanufacturing II, Berkeley, California, USA (2015)
  13. Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Continuous and semi-continuous production of MVA-virus in two-stage bioreactor systems. 24th Meeting of the European Society for Animal Cell Technology, ESACT 2015, Barcelona, Spain (2015)

Thesis - Dissertation (3)

  1. Heldt, S.: Mathematical Models of Influenza A Virus Infection: From Intracellular Replication to Virus Growth in Cell Populations. Dissertation, 186 pp., Otto-von-Guericke Universität, Magdeburg (2015)
  2. Peschel, B.: Infection dynamics and virus-induced apoptosis in influenza virus A infected adherent and suspension MDCK cells. Dissertation, 196 pp., Shaker, Aachen (2015)
 
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