Videos and Interviews

Creating Better Pharmaceutical Products for Society - EU Project CORE

The CORE Network aims to construct a toolbox to help industry design crystallisation processes for the separation of chiral pharmaceuticals molecules. Learn all about CORE and how it works directly from the researchers involved in the project.

Prof. Dr.-Ing. Kai Sundmacher on Sustainable Chemicals Production (Interview with Latest Thinking, 2018)

Prof. Kai Sundmacher's aim is to introduce a more sustainable process to chemicals production. As he explains in this video, for new technological developments in chemical process engineering a new methodology is needed that is able to include many decision variables in order to find the best pathway from the raw materials to the target product. Therefore, his research team developed an elementary process function (EPF) methodology which allows them to analyze the pathway of fluid elements and the goal is to steer this fluid element along an ideal pathway towards the final state, thereby discovering the most sensitive manipulating variables. Already, the researchers have found many real-world applications for this EPF methodology, such as in the chemicals production industry, in solids production and in biotechnology.

Prof. Dr.-Ing. Andreas Seidel-Morgenstern on the Separation of Enantiomers of a Chiral Molecule (Interview with Latest Thinking, 2017)

Chiral molecules are molecules that behave as image and mirror image to each other; these are also called enantiomers. There is a demand in pure enantiomers, which can be created for the use of a variety of industries, such as drugs for the pharmaceutical industry or herbicides for agrochemistry. ANDREAS SEIDEL-MORGENSTERN and his research team investigate access to these pure enantiomers. To achieve this, they work on separating the two enantiomers, complementing alternative approaches devoted to synthesize just one of them. For this, they use racemic mixtures – which contain equal amounts of left- and right-handed enantiomers of a chiral molecule – and then split these racemates. The separation process they managed to develop for this, as is described in this video, allows them to produce larger quantities of pure enantiomers from cheap available mixtures than was possible before. This means that these can now also be produced more effectively in industrial contexts.

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