Publications of Tanja Laske

Duvigneau, S.; Dürr, R.; Laske, T.; Bachmann, M.; Dostert, M.; Kienle, A.: Model-based approach for predicting the impact of genetic modifications on product yield in biopharmaceutical manufacturing—Application to influenza vaccine production. PLoS Computational Biology 16 (6), e1007810 (2020)

Rodrigues, A. F.; Fernandes, P.; Laske, T.; Castro, R.; Marques Alves, P.; Genzel, Y.; Coroadinha, A. S.: Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production. International Journal of Molecular Sciences 21 (17), 6111 (2020)

Laske, T.; Bachmann, M.; Dostert, M.; Karlas, A.; Wirth, D.; Frensing, T.; Meyer, T. F.; Hauser, H.; Reichl, U.: Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth. PLoS Computational Biology 15 (4), e1006944 (2019)

Rüdiger, D.; Kupke, S. Y.; Laske, T.; Zmora, P.; Reichl, U.: Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Computational Biology 15 (2), e1006819 (2019)

Tapia, F.; Laske, T.; Wasik, M.; Rammhold, M.; Genzel, Y.; Reichl, U.: Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling. Frontiers in Bioengineering and Biotechnology 7, 275 (2019)

Duvigneau, S.; Dürr, R.; Laske, T.; Bachmann, M.; Dostert, M.; Reichl, U.; Kienle, A.: Mathematical modeling as a tool to improve influenza vaccine production processes. FOSBE 2018, Chicago, Illinois, USA, August 05, 2018 - August 08, 2018. IFAC-PapersOnLine 51 (19), pp. 1 - 4 (2018)

Dürr, R.; Duvigneau, S.; Laske, T.; Bachmann, M.; Kienle, A.: Analyzing the Impact of Heterogeneity in Genetically Engineered Cell Lines for Influenza Vaccine Production Using Population Balance Modeling. Foundations of Systems Biology in Engineering - FOSBE 2016 — Magdeburg, Germany, 9—12 October 2016, Magdeburg, Germany, October 09, 2016 - October 12, 2016. IFAC-PapersOnLine 49 (26), pp. 225 - 230 (2016)

Laske, T.: Mathematical models of influenza A virus infection: Elucidating the impact of host cell factors and defective interfering particles on virus growth. Dissertation, Otto-von-Guericke-Universität, Magdeburg (2021)