Max Planck Institute for Dynamics of Complex Technical Systems

Publications of Yvonne Genzel

All genres

Journal Article (102)

2010

Journal Article

Vester, D., Rapp, E., Kluge, S., Genzel, Y., & Reichl, U. (2010)Virus-host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approachJournal of Proteomics, 73 (9), 1656–1669doi: 10.1016/j.jprot.2010.04.006.

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2009

Journal Article

Bock, A., Möhler, L., Sann, H., Schulze-Horsel, J., Genzel, Y., & Reichl, U. (2009)Growth behaviour of number distributed adherent MDCK cells for optimization in large scale microcarrier culturesBiotechnology Progress, 25 (6), 1717–1731doi: 10.1002/btpr.262.

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Journal Article

Genzel, Y. & Reichl, U. (2009)Continuous cell lines as production system for influenza vaccinesExpert Review of Vaccines, 8 (12), 1681–1692doi: 10.1586/erv.09.128.

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Journal Article

Lohr, V., Rath, A., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U. (2009)New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagationVaccine, 27 (36), 4975–4982doi: 10.1016/j.vaccine.2009.05.083.

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Journal Article

Schulze-Horsel, J., Schulze, M., Agalaridis, G., Genzel, Y., & Reichl, U. (2009)Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production – flow cytometry and mathematical modelingVaccine, 27 (20), 2712–2722doi: 10.1016/j.vaccine.2009.02.027.

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Journal Article

Schwarzer, J., Rapp, E., Hennig, R., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U. (2009)Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutininVaccine, 27 (32), 4325–4336doi: 10.1016/j.vaccine.2009.04.076.

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Journal Article

Vester, D., Rapp, E., Gade, D., Genzel, Y., & Reichl, U. (2009)Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell linesProteomics, 9 (12), 3316–3327doi: 10.1002/pmic.200800893.

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2008

Journal Article

Opitz, L., Zimmermann, A., Lehmann, S., Genzel, Y., Lübben, H., Reichl, U., & Wolff, M. W. (2008)Capture of cell culture-derived influenza virus by lectins: strain independent, but host cell dependentJournal of Virological Methods, 154 (1-2), 61–68doi: 10.1016/j.jviromet.2008.09.004.

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Journal Article

Ritter, J. B., Genzel, Y., & Reichl, U. (2008)Simultaneous extraction of several metabolites of energy metabolism and related substances in mammalian cells: Optimization using experimental designAnalytical Biochemistry, 373, 349–369doi: 10.1016/j.ab.2007.10.037.

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Journal Article

Schulze-Horsel, J., Genzel, Y., & Reichl, U. (2008)Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine productionBMC Biotechnology, 8, 45doi: 10.1186/1472-6750-8-45.

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publisher-version

Journal Article

Sidorenko, Y., Wahl, A., Dauner, M., Genzel, Y., & Reichl, U. (2008)Comparison of Metabolic Flux Distributions for MDCK Cell Growth in Glutamine- and Pyruvate-Containing MediaBiotechnology Progress, 24 (2), 311–320doi: 10.1021/bp0702673.

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Journal Article

Wahl, A., Sidorenko, Y., Dauner, M., Genzel, Y., & Reichl, U. (2008)Metabolic flux model for an anchorage-dependent MDCK cell line: Characteristic Growth Phases and Minimum Substrate Consumption Flux DistributionBiotechnology and Bioengineering, 101 (1), 135–152doi: 10.1002/bit.21873.

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2007

Journal Article

Hundt, B., Best, C., Schlawin, N., Kassner, H., Genzel, Y., & Reichl, U. (2007)Establishment of a mink enteritis vaccine production process in stirred-tank reactor and Wave Bioreactor microcarrier culture in 1-10 L scaleVaccine, 25 (20), 3987–3995doi: 10.1016/j.vaccine.2007.02.061.

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Journal Article

Kalbfuss, B., Genzel, Y., Wolff, M. W., Zimmermann, A., Morenweiser, R., & Reichl, U. (2007)Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccinesBiotechnology and Bioengineering, 97 (1), 73–85doi: 10.1002/bit.21139.

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2006

Journal Article

Genzel, Y., Fischer, M., & Reichl, U. (2006)Serum-free influenza virus production avoiding washing steps & medium exchange in large-scale microcarrier cultureVaccine, 24, 3261–3272doi: 10.1016/j.vaccine.2006.01.019.

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Journal Article

Genzel, Y., Olmer, R. M., Schäfer, B., & Reichl, U. (2006)Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free mediaVaccine, 24 (35-36), 6074–6087doi: 10.1016/j.vaccine.2006.05.023.

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Journal Article

Ritter, J. B., Genzel, Y., & Reichl, U. (2006)High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in cultureJournal of Chromatography B, 843 (2), 216–226doi: 10.1016/j.jchromb.2006.06.004.

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2005

Journal Article

Genzel, Y., Ritter, J. B., König, S., Alt, R., & Reichl, U. (2005)Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cellsBiotechnology Progress, 21 (1), 58–69doi: 10.1021/bp049827d.

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2004

Journal Article

Genzel, Y., Behrendt, I., König, S., Sann, H., & Reichl, U. (2004)Metabolism of MDCK Cells during cell growth and influenza virus production in large-scale microcarrier cultureVaccine, 22, 2202–2208doi: 10.1016/j.vaccine.2003.11.041.

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Journal Article

Genzel, Y., König, S., & Reichl, U. (2004)Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detectionAnalytical Biochemistry, 335, 119–125doi: 10.1016/j.ab.2004.08.020.

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