Publications of Mandy Bachmann
All genres
Journal Article (3)
2020
Journal Article
16 (6), e1007810 (2020)
Model-based approach for predicting the impact of genetic modifications on product yield in biopharmaceutical manufacturing—Application to influenza vaccine production. PLoS Computational Biology 2019
Journal Article
15 (4), e1006944 (2019)
Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth. PLoS Computational Biology 2016
Journal Article
100 (16), pp. 7181 - 7192 (2016)
Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells. Applied Microbiology and Biotechnology Conference Paper (2)
2018
Conference Paper
51 (19), pp. 1 - 4 (2018)
Mathematical modeling as a tool to improve influenza vaccine production processes. FOSBE 2018, Chicago, Illinois, USA, August 05, 2018 - August 08, 2018. IFAC-PapersOnLine 2016
Conference Paper
49 (26), pp. 225 - 230 (2016)
Analyzing the Impact of Heterogeneity in Genetically Engineered Cell Lines for Influenza Vaccine Production Using Population Balance Modeling. Foundations of Systems Biology in Engineering - FOSBE 2016 — Magdeburg, Germany, 9—12 October 2016, Magdeburg, Germany, October 09, 2016 - October 12, 2016. IFAC-PapersOnLine Thesis - PhD (1)
2019
Thesis - PhD
Charakterisierung der Influenzavirus-Vermehrung in genetisch veränderten humanen Zelllinien zur Optimierung der Impfstoffproduktion. Dissertation, Otto-von-Guericke-Universität, Magdeburg (2019)