Aktuelle Veröffentlichungen

Schulze, P.; Leschinsky, M.; Seidel-Morgenstern, A.; Lorenz, H.: Continuous Separation of Lignin from Organosolv Pulping Liquors: Combined Lignin Particle Formation and Solvent Recovery. Industrial and Engineering Chemistry Research 58, S. 3797 - 3810 (2019)
Benner, P.; Khoromskaia, V.; Khoromskij, B. N.; Yang, C.: Computing the Density of States for Optical Spectra of Molecules by Low-Rank and QTT Tensor Approximation. Journal of Computational Physics 382, S. 221 - 239 (2019)
Bremer, J.; Sundmacher, K.: Operation range extension via hot-spot control for catalytic CO2 methanation reactors. Reaction Chemistry & Engineering 6 (4), S. 1019 - 1037 (2019)
Dreimann, J. M.; Kohls, E.; Warmeling, H. F. W.; Stein, M.; Guo, L. F.; Garland, M.; Dinh, T. N.; Vorholt, A. J.: In Situ Infrared Spectroscopy as a Tool for Monitoring Molecular Catalyst for Hydroformylation in Continuous Processes. ACS Catalysis 9, S. 4308 - 4319 (2019)
Liesche, G.; Schack, D.; Sundmacher, K.: The FluxMax Approach for Simultaneous Process Synthesis and Heat Integration: Production of Hydrogen Cyanide. AIChE-Journal (angenommen)
Venayak, N.; Kamp von, A.; Klamt, S.; Mahadevan, R.: MoVE identifies metabolic valves to switch between phenotypic states. Nature Communications 9, 5332 (2018)
Sascha Young Kupke, Dietmar Riedel, Timo Frensing, Pawel Zmora, Udo Reichl
A novel type of influenza A virus-derived defective interfering particle with nucleotide substitutions in its genome

Veranstaltungen

Mit hochrangigen Wissenschaftlerinnen und Wissenschaftlern aus renommierten Forschungseinrichtungen deutschland- und weltweit.

MPI Kolloquiumsreihe 2019

Mit hochrangigen Wissenschaftlerinnen und Wissenschaftlern aus renommierten Forschungseinrichtungen deutschland- und weltweit. [mehr]

Willkommen am Max-Planck-Institut Magdeburg

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Vortrag

514 1429059225

Design of RNA-based regulators and their implementation into large synthetic gene circuits

Ligand-responsive gene switches are cellular sensors that process specific signals into adjusted gene product responses and transform mammalian cells into useful cell-based machines for next-generation biotechnological and biomedical applications. In this talk, I will present how mammalian cells engineered with such gene switches can readily applied for biotechnological and diagnostic purposes. The construction of larger synthetic gene circuits, however, requires an additional gene control layer to connect multiple switches. RNA-based gene switches are perfectly suited for this function because they act on translation rather than transcription. In this talk, I will present how to build such RNA-based gene switches and implement them into large gene circuits with network topologies reminiscent to electronics that provide engineered cells the ability to perform complex information-processing tasks. [mehr]

 
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