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Ivanov, I.; Lira, R. d.; Tang, D.; Franzmann, T.; Klosin, A.; Caire da Silva, L.; Hyman, A. A.; Landfester, K.; Lipowsky, R.; Sundmacher, K. et al.; Dimova, R.: Directed Growth of Biomimetic Microcompartments. Advanced Biosystems (angenommen)
Antoulas, A. C.; Zhu, B.; Zhang, Q.; York, B.; O'Malley, B. W.; Dacso, C. C.: A novel mathematical method for disclosing oscillations in gene transcription: A comparative study. PLoS ONE 13 (9), e0198503 (2018)
Venayak, N.; Kamp von, A.; Klamt, S.; Mahadevan, R.: MoVE identifies metabolic valves to switch between phenotypic states. Nature Communications 9, 5332 (2018)
Sascha Young Kupke, Dietmar Riedel, Timo Frensing, Pawel Zmora, Udo Reichl
A novel type of influenza A virus-derived defective interfering particle with nucleotide substitutions in its genome
Melnikov, S.; Stein, M.: Solvation and Dynamics of CO2 in Aqueous Alkanolamine Solutions. ACS Sustainable Chemistry & Engineering 7 (1), S. 1028 - 1037 (2019)
Münzberg, S.; Vu, T. G.; Seidel-Morgenstern, A.: Generalizing Countercurrent Processes: Distillation and Beyond. Chemie-Ingenieur-Technik 90 (11), S. 1769 - 1781 (2018)
Benner, P.; Qiu, Y.; Stoll, M.: Low-Rank Eigenvector Compression of Posterior Covariance Matrices for Linear Gaussian Inverse Problems. SIAM/ASA Journal on Uncertainty Quantification 6 (2), S. 965 - 989 (2018)


Mit hochrangigen Wissenschaftlerinnen und Wissenschaftlern aus renommierten Forschungseinrichtungen deutschland- und weltweit.

MPI Kolloquiumsreihe 2019

Mit hochrangigen Wissenschaftlerinnen und Wissenschaftlern aus renommierten Forschungseinrichtungen deutschland- und weltweit. [mehr]

Konferenzen 2019

18. bis 20. März 2019

YCOPE 2019

18. bis 20. März 2019 [mehr]

Willkommen am Max-Planck-Institut Magdeburg



514 1429059225

Design of RNA-based regulators and their implementation into large synthetic gene circuits

Ligand-responsive gene switches are cellular sensors that process specific signals into adjusted gene product responses and transform mammalian cells into useful cell-based machines for next-generation biotechnological and biomedical applications. In this talk, I will present how mammalian cells engineered with such gene switches can readily applied for biotechnological and diagnostic purposes. The construction of larger synthetic gene circuits, however, requires an additional gene control layer to connect multiple switches. RNA-based gene switches are perfectly suited for this function because they act on translation rather than transcription. In this talk, I will present how to build such RNA-based gene switches and implement them into large gene circuits with network topologies reminiscent to electronics that provide engineered cells the ability to perform complex information-processing tasks. [mehr]

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