Search results

Journal Article (5)

2021
Journal Article
Pech, S.; Rehberg, M.; Janke, R.; Benndorf, D.; Genzel, Y.; Muth, T.; Sickmann, A.; Rapp, E.; Reichl, U.: Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins. Applied Microbiology and Biotechnology 105 (5), pp. 1861 - 1874 (2021)
2014
Journal Article
Rath, A.; Rehberg, M.; Janke, R.; Genzel, Y.; Scholz, S.; Noll, T.; Rose, T.; Sandig, V.; Reichl, U.: The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells. Journal of Biotechnology 178, pp. 43 - 53 (2014)
2011
Journal Article
Janke, R.; Genzel, Y.; Händel, N.; Wahl, A.; Reichl, U.: Metabolic adaptation of MDCK cells to different growth conditions: Effects on catalytic activities of central metabolic enzymes. Biotechnology and Bioengineering 108 (11), pp. 2691 - 2704 (2011)
2010
Journal Article
Janke, R.; Genzel, Y.; Freund, S.; Wolff, M. W.; Grammel, H.; Rühmkorf, C.; Seidemann, J.; Wahl, A.; Reichl, U.: Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cells. Journal of Biotechnology 150 (3), pp. 396 - 403 (2010)
Journal Article
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Measurement of Key Metabolic Enzyme Activities in Mammalian Cells Using Rapid and Sensitive Microplate-Based Assays. Biotechnology and Bioengineering 107 (3), pp. 566 - 581 (2010)

Meeting Abstract (1)

2011
Meeting Abstract
Janke, R.; Genzel, Y.; Wetzel, M.; Reichl, U.: Effect of influenza virus infection on key metabolic enzyme activities in MDCK cells. In BMC Proceedings, 5 (S8 ), P129. 22nd European Society for Animal Cell Technology (ESACT) - Meeting on Cell Based Technologies , Vienna, Austria, May 15, 2011 - May 18, 2011. (2011)

Talk (5)

2012
Talk
Janke, R.; Genzel, Y.; Reichl, U.: A high-throughput assay to assess enzyme activity in central metabolism of production cell lines. Cell Culture Engineering XIII, Scottsdale, Arizona, USA (2012)
Talk
Rath, A.; Scholz, S.; Noll, T.; Janke, R.; Genzel, Y.; Rose, T.; Sandig, V.; Reichl, U.: Insights into mammalian energy metabolism: connecting intracellular metabolites and maximum enzyme activities. GVC/DECHEMA Vortrags- und Diskussionstagung - Biopharmazeutische Produktion, Freiburg (2012)
2011
Talk
Genzel, Y.; Janke, R.; Isken, B.; Rödig, J.; Rapp, E.; Lohr, V.; Behrendt, I.; Scharfenberg, K.; Kamen, A.; Schiedner, G. et al.; Jordan, I.; Reichl, U.: Influenza virus production: characteristics of different producer cell lines. 10th PEACe 2011, Cascais, Portugal (2011)
Talk
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Recombinant glycerokinase from Pichia farinosa: Intracellular expression, purification, characterization, and application. 1st European Congress of Applied Biotechnology, Berlin, Germany (2011)
2009
Talk
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Influence of cell culture medium on the catalytic activity of key enzymes in MDCK cells. 27. Jahrestagung der Biotechnologen, Mannheim, Germany (2009)

Poster (11)

2011
Poster
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Effects of different growth conditions on the catalytic activities of central metabolic enzymes in MDCK cells. 22nd ESACT Meeting, Vienna, Austria (2011)
Poster
Rath, A.; Prehm, C.; Janke, R.; Genzel, Y.; Sandig, V.; Rose, T.; Reichl, U.: Intracellular metabolite pools and enzyme activities of AGE1.HN.AAT cells during continuous cultivations. 22nd ESACT Meeting, Vienna, Austria (2011)
Poster
Streif, S.; Findeisen, R.; Zeiger, L.; Grammel, H.; Janke, R.; Genzel, Y.; Reichl, U.: WPT7: Model Validation, Parameter Analysis and Experimental Design. Part I: Parameter estimation and model invalidation using uncertain data. Part II: Redox Signaling in the facultative photosynthetic bacterium Rhodospirillum rubrum. Part III: Sensitive cycling assays for measuring key metabolic enyzme activities in MDCK cells. FORSYS/FORSYS Partner Status Seminar, Heidelberg, Germany (2011)
2010
Poster
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Changes in specific enzyme activities of MDCK cells during growth under different cultivation conditions. 8th European Symposium on Biochemical Engineering Science (ESBES), Bologna, Italy (2010)
2009
Poster
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Catalytic activity changes of key enzymes in MDCK cells under different growth conditions. 21st ESACT Meeting, Dublin, Ireland (2009)
Poster
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: A high-throughput platform to measure key enzyme activities in mammalian cells. German Symposium on Systems Biology, Heidelberg, Germany (2009)
Poster
Kremling, A.; Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: WPT7: Model Validation, Parameter Analysis and Experimental Design. Part I: Parameter estimation and parameter confidence intervalls. Part II: Key enzyme activities in central carbon metabolism of mammalian cells. Evaluation and Status Seminar FORSYS 2009, Heidelberg, Germany (2009)
2008
Poster
Janke, R.; Wahl, A.; Reichl, U.: Enzyme Activities in Central Carbon Metabolism of MDCK Cells under Different Growth Conditions. BioPerspectives, Hannover, Germany (2008)
Poster
Janke, R.; Wahl, A.; Reichl, U.: Determination of key enzyme activities in the central carbon metabolism of MDCK cells. ForSys Meeting, Berlin, Germany (2008)
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