English

apl. Prof. Dr. rer. nat. habil. Heike Lorenz


MPI Magdeburg


Address: Dr. Heike Lorenz
Max-Planck-Institut für Dynamik komplexer technischer Systeme
Sandtorstraße 1
D-39106 Magdeburg

Phone: +49 (0)391 6110-293
Fax: +49 (0)391 6110-524
E-mail: lorenz@mpi-magdeburg.mpg.de



Biografisches



Wissenschaftliche Preise/Stipendien/Mitgliedschaften

Forschungsinteressen

Ausgewählte Publikationen

2001 - 2004

/1/
Lorenz, H., Sheehan, P., Seidel-Morgenstern, A.: Coupling of simulated moving bed chromatography and fractional crystallisation for efficient enantioseparation.
Journal of Chromatography A 908 (2001), pp. 201-214
/2/
Kaspereit, M., Lorenz, H., Seidel-Morgenstern, A.: Coupling of simulated moving bed technology and crystallization to separate enantiomers.
In: Kaneko, K., Kanoh, H., Hanzawa, Y. (Eds.): Fundamentals of Adsorption 7, IK International Ltd., Shinjuko (Japan), 2002, pp. 101-108
/3/ Lorenz, H., Seidel-Morgenstern, A.: Binary and ternary phase diagrams of two enantiomers in solvent systems.
Thermochimica Acta 382 (2002), pp. 129-142
/4/
Mohan, R., Lorenz, H., Myerson, A.: Solubility Measurement Using Differential Scanning Calorimetry.
Ind. Eng. Chem. Res. 41 (2002), pp. 4854-4862
/5/ Lorenz, H., Sapoundjiev, D., Seidel-Morgenstern, A.: Solubility Equilibria in Chiral Systems and Their Importance for Enantioseparation.
Eng. Life Sci. 3 (2003), pp. 132-136
/6/ Lorenz, H., Seidel-Morgenstern, A.: A contribution to the mandelic acid phase diagram.
Thermochimica Acta, 415 (2004), pp. 55-61
/7/ Alvarez Rodrigo, A., Lorenz, H., Seidel-Morgenstern, A.: Online Monitoring of Preferential Crystallization of Enantiomers.
Chirality 16 (2004), pp. 499-508

2005 - 2008

/8/ Perlberg, A., Lorenz, H., Seidel-Morgenstern, A.: Crystal Growth Kinetics via Isothermal Seeded Batch Crystallization: Evaluation of Measurement Techniques and Application to Mandelic Acid in Water.
Ind. Eng. Chem. Res. 44 (2005), pp. 1012-1020
/9/ Gedicke, K., Beckmann, W., Brandt, A., Sapoundjiev, D., Lorenz, H., Budde, U., Seidel-Morgenstern, A.: Coupling chromatography and crystallization for efficient enantioseparation.
Adsorption 11 (2005), pp. 591–596
/10/ Sapoundjiev, D., Lorenz, H., Seidel-Morgenstern, A.: Determination of solubility data by means of calorimetry.
Thermochimica Acta 436 (2005), pp. 1–9
/11/ Perlberg, A., Lorenz, H., Seidel-Morgenstern, A.: Aspects of crystal growth in chiral systems on the example of mandelic acid in water.
VDI-Berichte 1901 (2005), pp. 689–694
/12/ Elsner, M. P., Alonso Muslera, E., Angelov, I., Fernández Menéndez, D., Lorenz, H., Polenske, Vollmer, U., Raisch, J., Seidel-Morgenstern, A.: Analysis of different crystalliser configurations to perform preferential crystallization.
VDI-Berichte 1901 (2005), pp. 829–835
/13/ Beckmann, W., Lorenz, H.: Partial miscibility of organic compounds in the solid state – the case of two epimers of a diastereomer.
Chem. Eng. Technol. 29 (2006), pp. 226–232
/14/ Lorenz, H., Perlberg, A., Sapoundjiev, D., Elsner, M. P., Seidel-Morgenstern, A.: Crystallization of enantiomers.
Chem. Eng. Process. 45 (2006), pp. 863–873
/15/ Czapla, F., Lorenz, H., Elsner, M. P., Seidel-Morgenstern, A.: Einfluss unterschiedlicher Prozessführungsstrategien auf die Produktivität und Produkteigenschaften bei der „Bevorzugten Kristallisation“.
In Teipel, U. (Hrsg.): Produktgestaltung in der Partikeltechnologie, Band 3, Fraunhofer-IRB-Verlag, Stuttgart, 2006, S. 219–235
/16/ Polenske, D., Elsner, M. P., Lorenz, H., Seidel-Morgenstern, A.: Alternative Einsatzmöglichkeiten der „Bevorzugten Kristallisation“ zur Enantiomerentrennung.
Chemie Ingenieur Technik 78 (2006), S. 1101–1110
/17/ Sapoundjiev, D., Lorenz, H., Seidel-Morgenstern, A.: Solubility of chiral threonine species in water/ethanol mixtures.
J. Chem. Eng. Data 51 (2006), pp. 1562–1566
/18/ Lorenz, H., Polenske, D., Seidel-Morgenstern, A.: Application of preferential crystallization to resolve racemic compounds in a hybrid process.
Chirality 18 (2006), pp. 828–840
/19/ Klose, F., Wolff, T., Lorenz, H., Seidel-Morgenstern, A., Suchorski, Y., Piorkowska, M., Weiss, H.: Active species on γ-alumina-supported vanadia catalysts:
Nature and reducibility. Journal of Catalysis 247 (2007), pp. 176–193
/20/ Gedicke, K., Kaspereit, M., Beckmann, W., Budde, U., Lorenz, H., Seidel-Morgenstern, A.: Conceptual design & feasibility study of combining continuous chromatography and crystallization for stereoisomer separations.
Chem. Eng. Res. Des. 85 (2007), pp. 928–936
/21/ Polenske, D., Lorenz, H., Seidel-Morgenstern, A.: Separation of propranolol hydrochloride enantiomers by preferential crystallization: thermodynamic basis and experimental verification.
Crystal Growth & Design 7 (2007), pp. 1628–1634
/22/ Seidel-Morgenstern, A., Lorenz, H., Polenske, D.: Method für separating compound-forming chiral systems.
Internationales (PCT) Patent WO 2007/023129 A3, published: 01. 03. 2007
/23/ Galvita, V., Hempel, T., Lorenz, H., Rihko-Struckmann, L. K., Sundmacher, K.: Deactivation of modified iron oxide materials in the cyclic water gas shift process for CO-free hydrogen production.
Ind. Eng. Chem. Res. 47 (2008), pp. 303-310
/24/ Czapla, F., Lorenz, H., Seidel-Morgenstern, A.: Einstellen der Partikelgrößenverteilung bei der Bevorzugten Kristallisation unter Berücksichtigung von Produktivitäts- und Reinheitsanforderungen.
In Teipel, U. (Hrsg.): Produktgestaltung in der Partikeltechnologie, Band 4, Fraunhofer-IRB-Verlag, Stuttgart, 2008, S. 235–250
/25/ Tulashie, S., Lorenz, H., Hilfert, L., Edelmann, F. T., Seidel-Morgenstern, A.: Potential of chiral solvents for enantioselective crystallization. 1. Evaluation of thermodynamic effects.
Crystal Growth & Design 8 (2008), pp. 3408–3414
/26/ Lorenz, H., Kaemmerer, H. (Eds.): BIWIC 2008: 15th International Workshop on Industrial Crystallization,
Shaker Verlag, Aachen, 2008

2009 - 2010

/27/ Czapla, F., Haida, H., Elsner, M. P., Lorenz, H., Seidel-Morgenstern, A.: Parameterization of population balance models for polythermal auto seeded preferential crystallization of enantiomers.
Chem. Eng. Sci. 64 (2009), pp. 753–763
/28/ Polenske, D., Lorenz, H., Seidel-Morgenstern, A.: Potential of different techniques of preferential crystallization for enantioseparation of racemic compound forming systems.
Chirality 21 (2009), pp. 728–737
/29/ Czapla, F., Lorenz, H., Seidel-Morgenstern, A.: Modellierung und Vergleich von polythermen autoseeded Prozessvarianten der Bevorzugten Kristallisation.
Chemie Ingenieur Technik 81 (2009), S. 839–848
/30/ Kaemmerer, H., Lorenz, H., Black, S., Seidel-Morgenstern, A.: Study of system thermodynamics and the feasibility of chiral resolution of the polymorphic system of malic acid enantiomers and its partial solid solutions.
Crystal Growth & Design 9 (2009), pp. 1851–1862
/31/ Tulashie, S., Lorenz, H., Seidel-Morgenstern, A.: Potential of chiral solvents for enantioselective crystallization. 2. Evaluation of kinetic effects.
Crystal Growth & Design 9 (2009), pp. 2387–2392
/32/ Polenske, D., Lorenz, H.: Solubility and metastable zone width of the methionine enantiomers and their mixtures in water.
J. Chem. Eng. Data 54 (2009), pp. 2272–2280
/33/ Kaemmerer, H., Lorenz, H., Seidel-Morgenstern, A.: Alternatives Verfahren zur Racemattrennung verbindungsbildender Systeme mittels Kristallisation
Chemie Ingenieur Technik 12 (2009), S. 1955–1965
/34/ Schotte, E., Lemin, B., Lorenz, H., Rau, H.: Gas Potentiometry – Oxygen Based Redox Process Diagnostics in High Temperature Environment.
In: Lackner, M., Winter, F., Agarwal, A. K. (Eds.): Handbook on Combustion, Vol. 2: Combustion Diagnostics and Pollutants, Wiley VCH, Weinheim, 2010, pp. 89–123
/35/ Polenske, D., Lorenz, H., Seidel-Morgenstern, A.: The binary phase diagram of propranolol hydrochloride and crystallization based enantioseparation.
J. Pharm. Sci. 99 (2010), pp. 1762–1773
/36/ Tulashie, S., Kaemmerer, H., Lorenz, H., Seidel-Morgenstern, A.: Solid-liquid equilibria of mandelic acid enantiomers in two chiral solvents – Experimental determination and model correlation.
J. Chem. Eng. Data 55 (2010), pp. 333–340
/37/ Kaemmerer, H., Tulashie, S., Lorenz, H., Seidel-Morgenstern, A.: Solid-liquid equilibria of N-methylephedrine enantiomers in two chiral solvents.
J. Chem. Eng. Data 55 (2010), pp.1131–1136
/38/ Czapla, F., Polenske, D., Klukas, L., Lorenz, H., Seidel-Morgenstern, A.: Cyclic auto seeded polythermal preferential crystallization – Effect of impurity accumulation.
Chem. Eng. Process. 49 (2010), pp. 22–28
/39/ Czapla, F., Kail, N., Öncül, A., Lorenz, H., Briesen, H., Seidel-Morgenstern, A.: Application of a recent FBRM-probe model to quantify preferential crystallization of DL-threonine.
Chem. Eng. Res. Des. 88 (2010)
/40/ von Langermann, J., Le Minh, T., Lorenz, H., Seidel-Morgenstern, A.: Kombination von Biokatalyse und Kristallisation zur Darstellung enantiomerenreiner Mandelsäurederivate.
Chemie Ingenieur Technik 82 (2010), S. 93–99
/41/ Sistla, V. S., von Langermann, J., Lorenz, H., Seidel-Morgenstern, A.: Application of classical resolution for separation of DL-serine.
Chem. Eng. Technol. 33 (2010), pp. 780–786
/42/ Le Minh, T., von Langermann, J., Lorenz, H., Seidel-Morgenstern, A.: Enantiomeric 3-chloromandelic acid system: Binary melting point phase diagram, ternary solubility phase diagrams and polymorphism.
J. Pharm. Sci. 99 (2010), pp. 4084–4095
/43/ Kaemmerer, H., Jones, M. J., Lorenz, H., Seidel-Morgenstern, A.: Selective crystallisation of a chiral compound-forming system – Solvent screening, SLE determination and process design.
Fluid Phase Equilibria 296 (2010), pp. 192–205
/44/ Gou, L., Robl, S., Leonhard, K., Lorenz, H., Sordo, M., Butka, A., Kesselheim, S., Wolff, M., Seidel-Morgenstern, A., Schaber, K.: A hybrid process for chiral separation of compound-forming systems.
Chirality 22 (2010)
/45/ Tulashie, S., Lorenz, H., Malwade, C., Seidel-Morgenstern, A.: Ternary solubility phase diagrams of mandelic acid and N-methylephedrine in chiral solvents with different carbon chain lengths.
Crystal Growth & Design 10 (2010), pp. 4023 – 4029
/46/ Tulashie, S., Lorenz, H., von Langermann, J., Seidel-Morgenstern, A.: Chiral task-specific solvents for mandelic acid and their impact on solution thermodynamics and crystallization kinetics.
Crystal Growth & Design, accepted