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Prof. Dr.-Ing. habil. Malte Kaspereit
 
Friedrich-Alexander-Universität Erlangen-Nürnberg  
Lehrstuhl für Thermische Verfahrenstechnik  
Egerlandstr. 3  
D-91058 Erlangen / Germany  
   
phone   +49 (0) 9131 85 27638  
fax       +49 (0) 9131 85 27 441  
email    cf. Uni Erlangen for address

Brief biography

2011    

Appointed as professor at Chair for Separation Science and Technology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

2011

Habilitation (lecturer qualification / post-doctoral thesis) at Otto-von-Guericke Universität Magdeburg, Germany. Topic: Synthesis and Design of Advanced Chromatographic Process Concepts

2006

Ph.D. from Otto-von-Guericke Universität Magdeburg. Topic: Separation of Enantiomers by a Process Combination of Chromatography and Crystallisation

1999

Diploma degree in Process Engineering from Technische Universität Clausthal, Germany

Research interests

My research focuses on the development of advanced separation processes and reactive separations, in particular for challenging separation problems.

Research topics in brief:

- Process integration on flowsheet and apparatus level
     - Optimal design of reactive and hybrid separation processes by NLP methods
     - in silico synthesis of such processes by MINLP methods
- Advanced operating modes and design methods for chromatographic processes
     - Simulated moving bed (SMB) processes
     - Steady-state recycling (SSR) processes
     - Reactive chromatography
- Local equilibrium theory for chromatography and integrated reaction-separation systems
- Enantioseparations

For students

Teaching

Bioseparation II (University Erlangen-Nürnberg, 2011)
Industrielle chromatographische Trennverfahren (Otto von Guericke University, 2009, 2010)
Adsorption und heterogene Katalyse (Otto von Guericke University, 2007-2009)

Possible topics for student/diploma/master projects

Students interested in performing a project at University Erlangen-Nürnberg should not hesitate to send an inquiry by email.

Selected Publications

A complete list of publications can be downloaded here: pdf ~50k


journal papers

M. Kaspereit, T. Sainio:
Simplified Design of Steady-State Recycling Chromatography Under Ideal and Nonideal Conditions,
Chemical Engineering Science (accepted/in press).

J. G. Palacios, B. Kramer, A. Kienle, M. Kaspereit:
Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers,
Journal of Chromatography A 1218 (2011) 2232-2239.

J. G. Palacios, M. Kaspereit, A. Kienle:
Integrated Simulated Moving Bed Processes for the Production of Single Enantiomers,
Chemical Engineering & Technology 34 (2011) 688-698.

J. Siitonen, T. Sainio, M. Kaspereit:
Theoretical analysis of steady state recycling chromatography with solvent removal,
Separation & Purification Technology 78 (2011) 21-32.

T. Sainio, M. Kaspereit: pdf ~600k
Analysis of steady state recycling chromatography using equilibrium theory,
Separation & Purification Technology 66 (2009) 9-18.

J. G. Palacios, M. Kaspereit, G. Ziomek, D. Antos, A. Seidel-Morgenstern:
Optimization and Analysis of Possible Column Arrangements for Multicomponent Separations by Preparative Chromatography,
Industrial & Engineering Chemistry Research 48 (2009) 11148-11157.

J. G. Palacios, M. Kaspereit, A. Kienle:
Conceptual Design of Integrated Chromatographic Processes for the Production of Single (Stereo-)Isomers,
Chemical Engineering & Technology 32 (2009) 1392-1402.

P. Forssén, R. Arnell, M. Kaspereit, A. Seidel-Morgenstern, T. Fornstedt:
Effects of a Strongly Adsorbed Additive on Process Performance in Chiral Preparative Chromatography,
Journal of Chromatography A 1212 (2008) 89-97.

A.A. Kulkarni, K.-P. Zeyer, T. Jacobs, M. Kaspereit, A. Kienle:
Feasibility studies and dynamics of catalytic liquid phase esterification reactions in a micro plant,
Chemical Engineering Journal 185S (2008) S270-S275.

M. Kaspereit, A. Seidel-Morgenstern, A. Kienle: pdf ~350k
Design of Simulated Moving Bed Chromatography Under Reduced Purity Requirements,
Journal of Chromatography A 1162 (2007) 2-13.

T. Sainio, M. Kaspereit, A. Kienle, A. Seidel-Morgenstern:
Thermal effects in reactive liquid chromatography,
Chemical Engineering Science 62 (2007) 5674-5681.

K. Gedicke, M. Kaspereit, W. Beckmann, U. Budde, H. Lorenz, A. Seidel-Morgenstern:
Conceptual Design & Fesibility Study of Combining Continuous Chromatography and Crystallisation for Stereoisomer Separations,
Chemical Engineering Research and Design 85 (2007) 928-936.

M. Kaspereit, K. Gedicke, V. Zahn, A.W. Mahoney, A. Seidel-Morgenstern:
Shortcut Method for Evaluation and Design of a Hybrid Process for Enantioseparations,
Journal of Chromatography A 1092 (2005) 55-64.

G. Ziomek, M. Kaspereit, J. Jezowski, A. Seidel-Morgenstern, D. Antos:
Effect of mobile phase composition on the SMB processes efficiency. Stochastic optimization of isocratic and gradient operation,
Journal of Chromatography A 1070 (2005) 111-124.

H. Schramm, A. Kienle, M. Kaspereit, A. Seidel-Morgenstern: pdf ~269k
Improved Operation of Simulated Moving Bed Processes through Cyclic Modulation of Feed Flow and Feed Concentration,
Chemical Engineering Science 58 (2003) 5217-5227.

H. Schramm, M. Kaspereit, A. Kienle, A. Seidel-Morgenstern:
Simulated moving bed process with cyclic modulation of the feed concentration,
Journal of Chromatography A 1006 (2003) 77-86.

H. Schramm, M. Kaspereit, A. Kienle, A. Seidel-Morgenstern: pdf ~88k
Verbesserter Betrieb von Simulated Moving Bed-Prozessen durch zyklische Modulation der Feedkonzentration,
Chemie-Ingenieur-Technik 74 (2003) 379-383.

M. Kaspereit, P. Jandera, M. Skavrada, A. Seidel-Morgenstern:
Impact of adsorption isotherm parameters on the performance of enantioseparation using simulated moving bed chromatography,
Journal of Chromatography 944 (2002) 249-262.

H. Schramm, M. Kaspereit, A. Kienle, A. Seidel-Morgenstern:
Improving Simulated Moving Bed Processes by Cyclic Modulation of the Feed Concentration,
Chemical Engineering & Technology 25 (2002), 1151-1155.

monographs

M. Kaspereit: pdf ~550k
Optimal Synthesis and Design of Advanced Chromatographic Process Concepts.
Habilitation, Otto-von-Guericke Universität Magdeburg. 2011.

M. Kaspereit:
Separation of Enantiomers by a Process Combination of Chromatography and Crystallisation.
PhD thesis, Otto-von-Guericke Universität Magdeburg. Shaker-Verlag, Aachen, 2006.

book chapters

M. Kaspereit, Advanced operating concepts for Simulated Moving Bed Processes, in: E. Grushka, N. Grinberg (Eds.), Advances in Chromatography, Vol. 47, CRC Press, Boca Raton, FL, USA; pp 165 - 192 (ISBN-10: 1420060368).

B. Schuur, M. Kaspereit, A.B. de Haan, M. Leeman, Chiral separations, in: M. Butler et al. (Eds.), Comprehensive Biotechnology, Elsevier, 2011 (ISBN-13: 978-0-444-53352-4).

reviews

A. Seidel-Morgenstern, L.C. Keßler, M. Kaspereit:
New Developments in Simulated Moving Bed Chromatography,
Chemical Engineering & Technology 31 (2008) 1 - 13.

A. Seidel-Morgenstern, L.C. Keßler, M. Kaspereit:
Neue Entwicklungen auf dem Gebiet der simulierten Gegenstromchromatographie,
Chemie-Ingenieur-Technik 6 (2008) 725 - 740.

selected conference contributions

peer-reviewed conference papers:

M. Kaspereit, J. G. Palacios, T. Meixus Fernandez, A. Kienle:
Systematic Design of Production Processes for Enantiomers with Integration of Chromatography and Racemisation Reactions (oral),
18th European Symposium on Computer Aided Process Engineering (ESCAPE 18), Lyon/France, June 1-4, Elsevier, Amsterdam, 2008, p. 97-102.

M. Kaspereit, H. Lorenz, A. Seidel-Morgenstern:
Coupling of simulated moving bed technology and crystallization to separate enantiomers (oral),
in: Fundamentals of adsorption, (Ed.) K. Kaneko et al., IK International Ltd., Shinjuko, Japan (2002) 101-108.




patents

H. Schramm, A. Kienle, M. Kaspereit, A. Seidel-Morgenstern: Method and Device for Chromatographic Component Separation     DE10235385, WO2004014511, EP1526907, US7479228


Colleagues & links

Dr. Tuomo Sainio ( Lappeenranta Technical University , Finland).

The European collaborative research project INTENANT I am currently involved in.



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