Aktuelle Veröffentlichungen

Petra Schwille, Joachim Spatz, Katharina Landfester, Eberhard Bodenschatz, Stephan Herminghaus,Victor Sourjik, Tobias Erb, Philippe Bastiaens, Reinhard Lipowsky, Anthony Hyman, Peter Dabrock, Jean-Christophe Baret, Tanja Vidakovic-Koch, Peter Bieling, Rumiana Dimova, Hannes Mutschler, Tom Robinson,Dora Tang, Seraphine Wegner, Kai Sundmacher
MaxSynBio ‐ Avenues towards creating cells from the bottom up
Angewandte Chemie, 11 May 2018
DOI: 10.1002/ange.201802288

Peter Benner, Venera Khoromskaia, and Boris N. Khoromskij
Range-Separated Tensor Format for Many-Particle Modeling
SIAM Journal on Scientific Computing, Vol. 40, Issue 2, 2018, pp. A1034–A1062.
DOI: 10.1137/16M1098930

Hannes K. Buchholz, Matthias Stein
Accurate lattice energies of organic molecular crystals from periodic turbomole calculations
Journal of Computational Chemistry, 5. März 2018, DOI: 10.1002/jcc.25205

Xing Liu, Justin M. Reitsma, Jennifer L. Mamrosh, Yaru Zhang, Ronny Straube, Raymond J. Deshaies
Cand1-mediated adaptive exchange mechanism enables variation in F-box protein expression
Molecular Cell, Volume 69, Issue 5, pp 773 - 786, 1. März 2018
DOI: 10.1016/j.molcel.2018.01.038

Susann Triemer, Kerry Gilmore, Giang T. Vu, Peter H. Seeberger, Andreas Seidel-Morgenstern
Literally green chemical synthesis of artemisinin from plant extracts
Angewandte Chemie International Edition, 21. Februar 2018
DOI: 10.1002/anie.201801424

Zu ausgewählten Publikationen ...

Veranstaltungen

Willkommen am Max-Planck-Institut Magdeburg

Nachrichten

Vortrag

514 1429059225

Design of RNA-based regulators and their implementation into large synthetic gene circuits

Ligand-responsive gene switches are cellular sensors that process specific signals into adjusted gene product responses and transform mammalian cells into useful cell-based machines for next-generation biotechnological and biomedical applications. In this talk, I will present how mammalian cells engineered with such gene switches can readily applied for biotechnological and diagnostic purposes. The construction of larger synthetic gene circuits, however, requires an additional gene control layer to connect multiple switches. RNA-based gene switches are perfectly suited for this function because they act on translation rather than transcription. In this talk, I will present how to build such RNA-based gene switches and implement them into large gene circuits with network topologies reminiscent to electronics that provide engineered cells the ability to perform complex information-processing tasks. [mehr]

 
Zur Redakteursansicht
loading content