Aktuelle Veröffentlichungen

Marian Weiss, Johannes Patrick Frohnmayer, Lucia Theresa Benk, Barbara Haller, Jan-Willi Janiesch, Thomas Heitkamp, Michael Börsch, Rafael B. Lira, Rumiana Dimova, Reinhard Lipowsky, Eberhard Bodenschatz, Jean-Christophe Baret, Tanja Vidakovic-Koch, Kai Sundmacher, Ilia Platzman, Joachim P. Spatz

Axel von Kamp und Steffen Klamt
Growth-coupled overproduction is feasible for almost all metabolites in five major production organisms
Nature Communications 8, 15926, 22. Juni 2017.
DOI: 10.1038/ncomms15956

Antonio Sorrentino, Tanja Vidakovic-Koch, Richard Hanke-Rauschenbach, Kai Sundmacher
Concentration-alternating frequency response: A new method for studying polymer electrolyte membrane fuel cell dynamics
Electrochimica Acta, Volume 243, 20. Juli 2017, pp. 53-64.
DOI: 10.1016/j.electacta.2017.04.150

Non-equimolar discrete compounds in binary chiral systems of organic substances
CrystEngComm, 2017,19, 1851-1869.
DOI: 10.1039/C6CE02209J
Open Access Article

Peter Benner , Albert Cohen, Mario Ohlberger, und Karen Willcox (Eds.)
Model Reduction and Approximation: Theory and Algorithms
SIAM Publications, Philadelphia, PA, 2017.

Peter Benner
System Reduction for Nanoscale IC Design
Springer International Publishing AG. 2017.
DOI: 10.1007/978-3-319-07236-4

Zu ausgewählten Publikationen ...

Veranstaltungen

WILLKOMMEN IN SACHSEN-ANHALT

Willkommen am Max-Planck-Institut Magdeburg

Nachrichten

Öffentliche Ausstellung zum Kunstprojekt “Emergenz”

Lange Nacht der Wissenschaft

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2. Lange Nacht der Wissenschaft 2007 in Magdeburg

Am Eingang des Max-Planck-Institutes wurden die Besucher mit einer feurigen Jonglageshow der Künstlergruppe DuoQuattroDuo begrüßt. Auch die Didgeridoo-Gruppe Waru verzauberte mit ihrer Weltmusik. Ca. 1000 Besucher waren gekommen, um das Max-Planck-Institut in kurzen, anschaulichen Vorträgen, geführten Hausrundgängen und Laborbesichtigungen kennenzulernen. [mehr]

15. Internationaler Workshop zur Industriellen Kristallisation

Lange Nacht der Wissenschaft

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4. Lange Nacht der Wissenschaft in Magdeburg

[mehr]

Lange Nacht der Wissenschaft

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5. Lange Nacht der Wissenschaft

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Begrüßungskolloquium für Prof. Dr. Peter Benner

Symposium: Analysis and Control of Infinite-Dimensional Systems in the Engineering Sciences (ACIDS)

Girls' Day – Der Mädchen-Zukunftstag

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Girls' Day – Der Mädchen-Zukunftstag

17 Schüler/innen der Klassenstufe 7 bis 9 nahmen an unserem Programm zum bundesweiten Girls' Day teil. Themenschwerpunkte waren die Vorstellung der natur- bzw. ingenieurwissenschaftlichen sowie technischen Berufsfelder und Arbeitsgebiete im Max-Planck-Institut. [mehr]

Schülerpraktikum

Lange Nacht der Wissenschaft

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6. Lange Nacht der Wissenschaft in Magdeburg

[mehr]

Schülerpraktikum

Schülerpraktikum

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Schülerpraktikum Verfahrenstechnik und Technische Kybernetik

30 Teilnehmerinnen und Teilnehmer der Klassenstufen 10 bis 12 [mehr]

Alumni Speed Informing Wege in den Beruf – Wie weiter nach Max Planck?

467 1429054075

Alumni Speed Informing Wege in den Beruf – Wie weiter nach Max Planck?

Neue Tagungsreihe der Max-Planck-Gesellschaft mit Alumni für Nachwuchswissenschaftler [mehr]

Girls' Day – Der Mädchen-Zukunftstag

468 1429054046

Girls' Day – Der Mädchen-Zukunftstag

17 Schüler/innen der Klassenstufe 7 bis 9 nahmen an unserem Programm zum bundesweiten Girls' Day teil. [mehr]

Lange Nacht der Wissenschaft

Schülerpraktikum

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Schülerpraktikum

[mehr]

Girls' Day – Der Mädchen-Zukunftstag

Lange Nacht der Wissenschaft

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8. Lange Nacht der Wissenschaft

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Schülerpraktikum

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Schülerpraktikum

[mehr]

Girls' Day – Der Mädchen-Zukunftstag

Schülerpraktikum

Lange Nacht der Wissenschaft

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9. Lange Nacht der Wissenschaft in Magdeburg

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Schülerpraktikum

Vortrag

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Innovation as Driving Force in Crop Protection Research

[mehr]

Vortrag

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From molecule to process: Model-based design of continuous centrifugal partition chromatography

[mehr]

Kolloquium

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Fusionsplasma im Dauerbetrieb: Das supraleitende Stellaratorprojekt Wendelstein 7-X

Die reproduzierbare Erzeugung heißer Wasserstoffplasmen (Ionen- und Elektronentemperatur einige 10 keV) ist die Voraussetzung für die Nutzung der Kernfusion als zukünftige Energiequelle. Der bisher erfolgreichste Weg basiert auf der Verwendung starker, toroidaler, verscherter Magnetfelder, die die geladenen Teilchen einschließen und so den Energieverlust durch Wandkontakt weitgehend vermeiden. Die beiden Konfigurationen, die sich über die lange Entwicklung durchgesetzt haben sind (a) der Tokamak und (b) der Stellarator. Beim Stellarator wird das Magnetfeld alleine durch externe Spulen erzeugt, beim Tokamak durch eine Kombination aus externen Spulen und starken Strömen im Hochtemperaturplasma. „Wendelstein 7-X“ ist der Name eines supraleitenden Stellarators, der sich seit etwa 15 Jahren am Max-Planck-Institut für Plasmaphysik in Greifswald im Aufbau befindet. Mit 30 m3 Plasmavolumen, 3T magnetischer Induktion auf der Achse und 10 MW Mikrowellenheizung können Wasserstoffplasmen erzeugt werden, die eine relevante Vorausschau auf ein künftiges Kraftwerk erlauben. Die Besonderheit dieses Experimentes ist, dass damit Hochleistungs-Fusionsplasmen für bis zu 30 min Dauer erzeugt werden können – bisher sind einige 10 s der Weltstandard. Der Vortrag führt kurz in die physikalischen und technischen Grundlagen der thermonuklearen Fusion und des magnetischen Einschlusses ein und beschreibt anschließend den – oftmals abenteuerlichen – Verlauf des Aufbaus dieses Großprojektes. Zentrale Aspekte wie kryogene Technologien, Supraleitung und hochbelastete Stahlstrukturen werden beleuchtet und die wesentlichen wissenschaftlichen Fragestellungen diskutiert, die mit Wendelstein 7-X beantwortet werden sollen. Am Schluß des Vortrages werden die Lehren zusammengefaßt, die sich aus dem Projektverlauf ziehen lassen und die durchaus generischen Charakter für wissenschaftliche Großprojekte haben. (in german or english, depending on the audience) [mehr]

Vortrag

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Post-Combustion CO2 Capture by Adsorption Processes

Post-combustion power plants are the major sources of CO2 emissions. Given that fossil fuels will be the major sources of energy in the next few years, capture of CO2 from these sources for sequestration could be a possible short term solution for abating greenhouse gas emissions. Pressure/Vacuum swing adsorption (P/VSA) processes using solid sorbents are considered as viable options. The presentation will have two parts. In the first, we report the systematic procedure for the synthesis of a P/VSA processes for dry CO2/N2 separation using zeolite 13X as adsorbent. Using equilibrium and kinetic parameters obtained in the laboratory, we screen several processes for adsorptive post-combustion capture. Based on multi-objective we identify the process that provides the best productivity-energy consumption trade-off. This process is then scaled for pilot-plant demonstration. These represent the first reports in the open-literature of an adsorptive process that achieves the purity and recovery targets set by the US Department of Energy in a single-stage process. The second part of the work deals with the issue of CO2 capture from wet flue gas. We report our recent results of developing a two-sorbent process for this purpose. We show that it is possible to capture CO2 from wet flue gas and discuss the additional energy that is required to achieve this. [mehr]

Kolloquium

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Optimality and Robustness of Signaling in Microorganisms

The Microbial Network group at the Max Planck Institute for Terrestrial Microbiology in Marburg focuses on quantitative analysis of cellular networks and their dynamics in microorganisms. The group is particularly interested in elucidating mechanisms that enable cellular networks to sensitively detect and integrate multiple extra- and intracellular cues, to robustly function in noisy and perturbing environments, and to plastically adjust their function dependent on the environment. Ultimately, the researchers would like to understand how the structure and function of the network have been shaped by the evolutionary selection. As model systems, the group uses chemotaxis, sugar uptake and two-component signaling in bacteria, as well as the mating behavior in budding yeast. [mehr]

Kolloquium

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Analytical Sciences in Action

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Vortrag

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Design of RNA-based regulators and their implementation into large synthetic gene circuits

Ligand-responsive gene switches are cellular sensors that process specific signals into adjusted gene product responses and transform mammalian cells into useful cell-based machines for next-generation biotechnological and biomedical applications. In this talk, I will present how mammalian cells engineered with such gene switches can readily applied for biotechnological and diagnostic purposes. The construction of larger synthetic gene circuits, however, requires an additional gene control layer to connect multiple switches. RNA-based gene switches are perfectly suited for this function because they act on translation rather than transcription. In this talk, I will present how to build such RNA-based gene switches and implement them into large gene circuits with network topologies reminiscent to electronics that provide engineered cells the ability to perform complex information-processing tasks. [mehr]

Kolloquium

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Design and Discovery of Structural Materials on the Computer: Prospects and Challenges

A key requirement in developing systematic tools to explore and predict properties of materials not yet synthesized is the availability of accurate computational tools determining energies not only at T = 0 K but also under realistic conditions. Combining accurate first principles calculations with meso­scopic/ macroscopic thermodynamic and/or kinetic concepts allows now to address this issue and to determine free energies and derived thermodynamic quantities. In the talk it will be shown how novel sampling strategies in configuration space together with highly converged density-functional theory calculations allow an unbiased and accurate determination of all relevant temperature dependent free energy contributions. The flexibility and the predictive power of these approaches and the impact they can have in developing new strategies in materials design will be discussed for modern ultra-high strength steels, light weight metallic alloys such as Mg-based alloys as well as in understanding the origins of failure mechanisms such as hydrogen embrittlement. [mehr]

DECHEMA-Kolloquium: Power-to-Chemicals

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DECHEMA-Kolloquium

"PEM Elektrolyse - Ein Schlüsselprozess für verschiedene Speicheranwendungen" Dr. Andreas Reiner, Siemens AG, Erlangen "Intelligente Integration von Ökostrom - Erfahrungen von industriellen Power-to-Gas-Anlagen im Bereich Methan und Wasserstoff" Dipl. Ing. Stefan Rieke, ETOGAS GmbH, Stuttgart "Die direkte Methanolsynthese - Energieeffizienz, Wirtschaftlichkeit und industrielle Kompatibilität" Dr. Peter Grauer, Silicon Fire AG, Schweiz "Fischer-Tropsch Synthese im Einsatz für Power-to-Liquid - Herausforderungen an Katalyse und Prozesstechnik" Prof. Peter Pfeifer, KIT, Karlsruhe Von 14.00 bis 14.45 Uhr haben die TeilnehmerInnen Gelegenheit zu einem Übersichtsrundgang durch das Max-Planck-Institut Magdeburg. Ihre Anmeldungen richten Sie bitte an Gabriele Ebel, Presse- und Öffentlichkeitsarbeit, ebel@mpi-magdeburg.mpg.de, 0391 - 61 10 144 [mehr]

Lange Nacht der Wissenschaft

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10. Lange Nacht der Wissenschaft

Alle Wissenschaftsinsitutionen in Magdeburg präsentieren sich zum 10. Mal gemeinsam auf der Langen Nacht der Wissenschaft [mehr]

Kolloquium

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MPI Kolloquiumsreihe: Mesh moving methods for multiphase problems

Multiphase flows including strong interface effects like surface tension have a wide range of applications. How to represent the geometry (i.e. the free boundary) constitutes the main design decision for a solution strategy for this type of problems. We review certain strategies with an emphasis on so called mesh moving methods. Several real world applications are presented that are solved effectively by this mesh moving method. In the presentation the ingredients of the methods like ALE, node doubling and subspace projection method are discussed. [mehr]

GAMM Workshop Applied and Numerical Linear Algebra

Kolloquium

1948 1447321899

MPI Kolloquiumsreihe: Plant-Based Biopharmaceuticals: How to Move New Product Candidates Towards Translational Research and Market

The development of recombinant antibodies and vaccines has allowed us to treat and prevent a large number of life-threatening diseases. However, as things stand in 2015, the speed, capacity and scalability of current production systems is beginning to place limitations on this crucial technology. The large-scale production of antibodies, vaccines and other pharmaceutical recombinant proteins is restricted by the industry’s current reliance on fermenter technology, particularly the culture of mammalian cells. This expensive and time-consuming production platform is preventing the distribution of recombinant protein drugs to those most in need. One way in which the above limitations can be addressed is through the use of plants and plant-based expression systems for rapid recombinant pharmaceutical protein production. The economic production of plant-based pharmaceuticals depends on satisfactory yields and product quality. This presentation will discuss the latest development in antibody and vaccine development and their production by molecular farming, focusing particularly on strategies to maximize protein yields during upstream production and optimize protein recovery in the downstream processing steps. Such strategies often involve careful consideration of how the protein is expressed and targeted within the plant cell, a factor which affects yield, stability, quality and ease of isolation. Our long-term objective is to ensure that next generation of plantbased production systems for recombinant proteins will create the opportunity to deliver antibodies, vaccines and other biopharmaceuticals beyond the industrialized nations and into the developing world. Several case studies will be presented: HIV antibodies were chosen to undergo fast-track development, including risk assessment, expression in tobacco, scale-up, downstream processing and regulatory development, with the aim of performing clinical trials. In addition use of engineered plant cells for human vaccine candidates will be discussed. Pharma-Planta is an EU Sixth Framework Integrated Project whose primary goal is to develop an approved production pipeline for plant-derived pharmaceutical proteins (PDPs). Although previous research has provided proof of the PDP concept, Pharma-Planta aims to develop an entire production chain by taking candidate pharmaceutical molecules from the expression platform through all stages of production and processing, ultimately to initiate phase I human trials in Europe. The Pharma-Planta Consortium comprised 40 interacting groups representing 33 public institutes and SMEs from 11 European Member States and South Africa. At the beginning of the project, eight target molecules were chosen representing four key indication areas including HIV. From these molecules, two HIV antibodies were chosen to undergo fast-track development, which would include risk assessment, cloning, expression and optimization of production in plants, scale-up, downstream processing and regulatory development, with the aim of submitting at least one of them for clinical trials within the five years of the program. Two HIV neutralizing antibodies have been expressed successfully in the two main production crops being developed within the consortium – maize and tobacco. One of these antibodies, 2G12, has been expressed at levels greater 100 mg per kg of plant material. The plant-derived antibodies remain stable and functional and retain their neutralizing activity. The consortium has investigated novel upscaling and downstream processing strategies to provide multiple grams clinical grade antibody material for human clinical trials. Preclinical trials in rabbits have been completed successfully and we also conducted successfully a phase I clinical trial in the UK. This work will now be moved forward for a phase IIa clinical trial which is funded by an Advanced ERC grant from the European Commission. We have also developed an interesting multi-stage malaria vaccine and neutralizing rabies antibody candidates and will discuss how both products have matured over the years both in performance and in manufacturing with the aim in mind to bring these two products into translational research within the next months. Finally state of the art technology developments to accelerate the development and production of PMPs as well as regulatory issues will be discussed. Along this line an innovative new manufacturing concept using LED lighting in a vertical farm concept have been developed. [mehr]

Doktorandenseminar Adsorption

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Doktorandenseminar Adsorption

Gruppe Physikalisch-Chemische Grundlagen der Prozesstechnik [mehr]

IMPRS Summer School on Process Systems Engineering 2015

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IMPRS Summer School on Process Systems Engineering 2015

From August 31 - September 04 the 4th Summer School of the IMPRS Magdeburg will take place here at the MPI. The topic of the Summer School is "Process Systems Engineering". [mehr]

Summer School

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Hybrid Modeling Summer School 2015

Hybrid modeling for the efficient design and operation of biochemical processes [mehr]

MPG Ausbildertagung (Verwaltung)

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MPG Ausbildertagung (Verwaltung)

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Homogeneous Catalytic In-Situ Spectroscopic Measurements and Chemometrics - An Overview of Activities at the National Laboratories in Singapore (A*STAR)

Vortrag: Processing of functional nanoparticles: From automated synthesis to tailored surface properties and applications

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Vortrag: Processing of functional nanoparticles: From automated synthesis to tailored surface properties and applications

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Kolloquium

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MPI Kolloquiumsreihe: Life Cycle of Artemisinin: from extraction to derivatisation and drug activity

Dieser Vortrag ist Teil der Kolloquiumsreihe am Max-Planck-Institut Magdeburg. Alle Interessierten sind herzlich eingeladen. [mehr]

3474 1446738750

11. Lange Nacht der Wissenschaft in Magdeburg

Das Max-Planck-Institut Magdeburg öffnet seine Labore, Werkstätten, das Technikum und den Rechencluster otto zur 11. Langen Nacht der Wissenschaft in Magdeburg am 21. Mai 2016 von 18.00 bis 1.00 Uhr. Für kleine Forscher bieten wir Wissenschaft zum Anfassen auf unserer Experimentierstraße und zum Anschauen in geführten Rundgängen. Die großen Wissenschaftsfans erfahren in unseren Laboren und in Vorträgen den Stand unserer Forschung. [mehr]

Reduced Basis Summer School

GlycoBioTec Symposium 2017

Schülerpraktikum "Verfahrenstechnik und Technische Kybernetik" Ostern 2017

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12. Lange Nacht der Wissenschaft in Magdeburg

Das Max-Planck-Institut Magdeburg öffnet seine Labore, Werkstätten, das Technikum und den Rechencluster otto zur 12. Langen Nacht der Wissenschaft in Magdeburg am 20. Mai 2017 von 18.00 bis 1.00 Uhr. Für kleine Forscher bieten wir Wissenschaft zum Anfassen auf unserer Experimentierstraße und zum Anschauen in geführten Rundgängen. Die großen Wissenschaftsfans erfahren in unseren Laboren und in Vorträgen den Stand unserer Forschung. [mehr]

5. Summer School der International Max Planck Research School Magdeburg: “Decision making and uncertainty”

Schülerpraktikum "Verfahrenstechnik und Technische Kybernetik" Herbst 2017

Schülerpraktikum "Verfahrenstechnik und Technische Kybernetik" 2018

13. Lange Nacht der Wissenschaft in Magdeburg

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13. Lange Nacht der Wissenschaft in Magdeburg

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