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Peter Benner, Venera Khoromskaia, and Boris N. Khoromskij
Range-Separated Tensor Format for Many-Particle Modeling
SIAM Journal on Scientific Computing, Vol. 40, Issue 2, 2018, pp. A1034–A1062.
DOI: 10.1137/16M1098930

Hannes K. Buchholz, Matthias Stein
Accurate lattice energies of organic molecular crystals from periodic turbomole calculations
Journal of Computational Chemistry, 5. März 2018, DOI: 10.1002/jcc.25205

Xing Liu, Justin M. Reitsma, Jennifer L. Mamrosh, Yaru Zhang, Ronny Straube, Raymond J. Deshaies
Cand1-mediated adaptive exchange mechanism enables variation in F-box protein expression
Molecular Cell, Volume 69, Issue 5, pp 773 - 786, 1. März 2018
DOI: 10.1016/j.molcel.2018.01.038

Susann Triemer, Kerry Gilmore, Giang T. Vu, Peter H. Seeberger, Andreas Seidel-Morgenstern
Literally green chemical synthesis of artemisinin from plant extracts
Angewandte Chemie International Edition, 21. Februar 2018
DOI: 10.1002/anie.201801424

Björn-Johannes Harder, Katja Bettenbrock, Steffen Klamt
Temperature-dependent dynamic control of the TCA cycle increases volumetric productivity of itaconic acid production by Escherichia coli.
Biotechnology and Bioengineering, Volume 115, Ausgabe 1, Seiten 156–164, Januar 2018, DOI: 10.1002/bit.26446
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CELLULAR and MOLECULAR BIOTECHNOLOGY

Synthetic Biology is heralded as a novel approach to the engineering of biosystems that will set the scene for a flourishing knowledge-based bio-economy. Benefits for the fundamental understanding of biological phenomena are also claimed, as rational construction of a system based on hypothesized design principles can be used to test assumptions. The keywords of synthetic biology are rational design, decoupling of conception and fabrication, standardization and component re-use, modularity and hierarchy, orthogonality and context-insensitivity. However, each keyword raises questions of desirability and feasibility. These questions remain ongoing areas of inquiry for the field and require multi-faceted approaches. Beyond the current hype surrounding it, what is the value of synthetic biology for the progress in understanding of biological systems and for the establishment of new biotechnological production platforms? [mehr]

 
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