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Marian Weiss, Johannes Patrick Frohnmayer, Lucia Theresa Benk, Barbara Haller, Jan-Willi Janiesch, Thomas Heitkamp, Michael Börsch, Rafael B. Lira, Rumiana Dimova, Reinhard Lipowsky, Eberhard Bodenschatz, Jean-Christophe Baret, Tanja Vidakovic-Koch, Kai Sundmacher, Ilia Platzman, Joachim P. Spatz

Axel von Kamp und Steffen Klamt
Growth-coupled overproduction is feasible for almost all metabolites in five major production organisms
Nature Communications 8, 15926, 22. Juni 2017.
DOI: 10.1038/ncomms15956

Antonio Sorrentino, Tanja Vidakovic-Koch, Richard Hanke-Rauschenbach, Kai Sundmacher
Concentration-alternating frequency response: A new method for studying polymer electrolyte membrane fuel cell dynamics
Electrochimica Acta, Volume 243, 20. Juli 2017, pp. 53-64.
DOI: 10.1016/j.electacta.2017.04.150

Non-equimolar discrete compounds in binary chiral systems of organic substances
CrystEngComm, 2017,19, 1851-1869.
DOI: 10.1039/C6CE02209J
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Peter Benner , Albert Cohen, Mario Ohlberger, und Karen Willcox (Eds.)
Model Reduction and Approximation: Theory and Algorithms
SIAM Publications, Philadelphia, PA, 2017.

Peter Benner
System Reduction for Nanoscale IC Design
Springer International Publishing AG. 2017.
DOI: 10.1007/978-3-319-07236-4

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CELLULAR and MOLECULAR BIOTECHNOLOGY

Synthetic Biology is heralded as a novel approach to the engineering of biosystems that will set the scene for a flourishing knowledge-based bio-economy. Benefits for the fundamental understanding of biological phenomena are also claimed, as rational construction of a system based on hypothesized design principles can be used to test assumptions. The keywords of synthetic biology are rational design, decoupling of conception and fabrication, standardization and component re-use, modularity and hierarchy, orthogonality and context-insensitivity. However, each keyword raises questions of desirability and feasibility. These questions remain ongoing areas of inquiry for the field and require multi-faceted approaches. Beyond the current hype surrounding it, what is the value of synthetic biology for the progress in understanding of biological systems and for the establishment of new biotechnological production platforms? [mehr]

 
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