Aktuelle Veröffentlichungen

Alexander Nikolay, Arnaud Léon, Klaus Schwamborn, Yvonne Genzel, Udo Reichl
Applied Microbiology and Biotechnology, 08 August, 2018
DOI: 10.1007/s00253-018-9275-z

Eric Schulze and Matthias Stein
Simulation of Mixed Self-Assembled Monolayers on Gold: Effect of Terminal Alkyl Anchor Chain and Monolayer Composition
The Journal of Physical Chemistry B, 122 (31), pp 7699–7710, published online 20 July 2018
DOI: 10.1021/acs.jpcb.8b05075

Peter Benner, Pawan Goyal, and Serkan Gugercin
H2-Quasi-Optimal Model Order Reduction for Quadratic-Bilinear Control Systems
SIAM Journal on Matrix Analysis and Applications, Vol. 39, Issue 2, pp. 983-1032, published online 5 June 2018
DOI: 10.1137/16M1098280

Thomas Beneyton, Dorothee Krafft, Claudia Bednarz, Christin Kleineberg, Christian Woelfer, Ivan Ivanov, Tanja Vidakovic-Koch, Kai Sundmacher und Jean-Christophe Baret
Out-of-equilibrium microcompartments for the bottom-up integration of metabolic functions
Nature Communications, 19 June 2018
DOI: 10.1038/s41467-018-04825-1

Petra Schwille, Joachim Spatz, Katharina Landfester, Eberhard Bodenschatz, Stephan Herminghaus,Victor Sourjik, Tobias Erb, Philippe Bastiaens, Reinhard Lipowsky, Anthony Hyman, Peter Dabrock, Jean-Christophe Baret, Tanja Vidakovic-Koch, Peter Bieling, Rumiana Dimova, Hannes Mutschler, Tom Robinson,Dora Tang, Seraphine Wegner, Kai Sundmacher
MaxSynBio ‐ Avenues towards creating cells from the bottom up
Angewandte Chemie, 11 May 2018
DOI: 10.1002/ange.201802288

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CELLULAR and MOLECULAR BIOTECHNOLOGY

Synthetic Biology is heralded as a novel approach to the engineering of biosystems that will set the scene for a flourishing knowledge-based bio-economy. Benefits for the fundamental understanding of biological phenomena are also claimed, as rational construction of a system based on hypothesized design principles can be used to test assumptions. The keywords of synthetic biology are rational design, decoupling of conception and fabrication, standardization and component re-use, modularity and hierarchy, orthogonality and context-insensitivity. However, each keyword raises questions of desirability and feasibility. These questions remain ongoing areas of inquiry for the field and require multi-faceted approaches. Beyond the current hype surrounding it, what is the value of synthetic biology for the progress in understanding of biological systems and for the establishment of new biotechnological production platforms? [mehr]

 
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