Journal Article (338)

2008
Journal Article
Schwarzer, J.; Rapp, E.; Reichl, U.: N-Glycan Analysis by CGE-LIF – Profiling Influenza A Virus Hemagglutinin N-Glycosylation during Vaccine Production. Electrophoresis 29 (20), pp. 4203 - 4214 (2008)
Journal Article
Sidorenko, Y.; Antoniukas, L.; Schulze-Horsel, J.; Reichl, U.: Mathematical model of growth and heterologous hantavirus protein production of the recombinant yeast Saccharomyces cerevisiae. Engineering in Life Sciences 8 (4), pp. 399 - 414 (2008)
Journal Article
Sidorenko, Y.; Schulze-Horsel, J.; Voigt, A.; Reichl, U.; Kienle, A.: Stochastic Population Balance Modeling of Influenza Virus Replication in Vaccine Production Processes. Chemical Engineering Science 63, pp. 157 - 169 (2008)
Journal Article
Sidorenko, Y.; Voigt, A.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Stochastic population balance modeling of influenza virus replication in vaccine production processes. II. Detailed description of the replication mechanism. Chemical Engineering Science 63 (8), pp. 2299 - 2304 (2008)
Journal Article
Sidorenko, Y.; Wahl, A.; Dauner, M.; Genzel, Y.; Reichl, U.: Comparison of Metabolic Flux Distributions for MDCK Cell Growth in Glutamine- and Pyruvate-Containing Media. Biotechnology Progress 24 (2), pp. 311 - 320 (2008)
Journal Article
Wahl, A.; Sidorenko, Y.; Dauner, M.; Genzel, Y.; Reichl, U.: Metabolic flux model for an anchorage-dependent MDCK cell line: Characteristic Growth Phases and Minimum Substrate Consumption Flux Distribution. Biotechnology and Bioengineering 101 (1), pp. 135 - 152 (2008)
Journal Article
Wahl, S. A.; Nöh, K.; Wiechert, W.: 13C labeling experiments at metabolic nonstationary conditions: an exploratory study. BMC Bioinformatics 9, p. 152 (2008)
Journal Article
Wolff, M. W.; Reichl, U.: Downstream Processing: From egg to cell culture-derived influenza virus particles. Chemical Engineering and Technology 31 (6), pp. 846 - 857 (2008)
2007
Journal Article
Bandaru, K. S.V.S.R.; Keßler, L. C.; Wolff, M. W.; Reichl, U.; Seidel-Morgenstern, A.; Pushpavanam, S.: Hydrodynamic characteristics and expansion behavior of beds containing single and binary-mixtures of particles. Industrial and Engineering Chemistry Research 46 (13), pp. 4686 - 4694 (2007)
Journal Article
Hundt, B.; Best, C.; Schlawin, N.; Kassner, H.; Genzel, Y.; Reichl, U.: Establishment of a mink enteritis vaccine production process in stirred-tank reactor and Wave Bioreactor microcarrier culture in 1-10 L scale. Vaccine 25 (20), pp. 3987 - 3995 (2007)
Journal Article
Kalbfuss, B.; Genzel, Y.; Wolff, M. W.; Zimmermann, A.; Morenweiser, R.; Reichl, U.: Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccines. Biotechnology and Bioengineering 97 (1), pp. 73 - 85 (2007)
Journal Article
Kalbfuss, B.; Wolff, M. W.; Geisler, L.; Tappe, A.; Wickramasinghe, R.; Thom, V.; Reichl, U.: Direct capture of influenza A virus from cell culture supernatant with Sartobind anion-exchange membrane adsorbers. Journal of Membrane Science 299, pp. 251 - 260 (2007)
Journal Article
Kalbfuss, B.; Wolff, M. W.; Morenweiser, R.; Reichl, U.: Purification of cell culture-derived human influenza A virus by size-exclusion and anion-exchange chromatography. Biotechnology and Bioengineering 96, pp. 932 - 944 (2007)
Journal Article
Nischang, I.; Reichl, U.; Seidel-Morgenstern, A.; Tallarek, U.: Concentration Polarization and Nonequilibrium Electroosmotic Slip in Dense Multiparticle Systems. Langmuir 23 (18), pp. 9271 - 9281 (2007)
Journal Article
Noack, S.; Wahl, A.; Qeli, E.; Wiechert, W.: Visualizing Regulatory Interactions in Metabolic Networks. BMC Biology 5, p. 46 (2007)
Journal Article
Opitz, L.; Lehmann, S.; Zimmermann, A.; Reichl, U.; Wolff, M. W.: Impact of adsorbents selection on affinity purification efficiency of cell culture derived human Influenza viruses. Journal of Biotechnology 131 (3), pp. 309 - 317 (2007)
Journal Article
Opitz, L.; Salaklang, J.; Büttner, H.; Reichl, U.; Wolff, M. W.: Lectin-affinity chromatography for downstream processing of MDCK cell culture derived human influenza A viruses. Vaccine 25 (5), pp. 939 - 947 (2007)
Journal Article
Pohlscheidt, M.; Langer, U.; Minuth, T.; Bödeker, B.; Apeler, H.; Hörlein, H. D.; Paulsen, D.; Rübsamen-Waigmann, H.; Henzler, H. J.; Reichl, U.: Development and optimisation of a procedure for the production of Parapoxvirus Ovis by large scale microcarrier cell culture in a non animal, non human and non plant derived medium. Vaccine 26 (12), pp. 1552 - 1565 (2007)
2006
Journal Article
Antoniukas, L.; Grammel, H.; Reichl, U.: Production of hantavirus Puumala nucleocapsid protein in Saccharomyces cerevisiae for vaccine and diagnostics. Journal of Biotechnology 124 (2), pp. 347 - 362 (2006)
Journal Article
Genzel, Y.; Fischer, M.; Reichl, U.: Serum-free influenza virus production avoiding washing steps & medium exchange in large-scale microcarrier culture. Vaccine 24, pp. 3261 - 3272 (2006)
Journal Article
Genzel, Y.; Olmer, R. M.; Schäfer, B.; Reichl, U.: Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media. Vaccine 24 (35-36), pp. 6074 - 6087 (2006)
Journal Article
Heßeler, J.; Schmidt, J. K.; Reichl, U.; Flockerzi, D.: Coexistence in the Chemostat as a result of metabolic by-products. Journal of mathematical biology 53 (4), pp. 556 - 584 (2006)
Journal Article
Kalbfuss, B.; Reichl, U.: Preparative Size-Exclusion Chromatography. GIT Laboratory Journal Europe 10 (4), pp. 18 - 20 (2006)
Journal Article
Ritter, J. B.; Genzel, Y.; Reichl, U.: High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in culture. Journal of Chromatography B 843 (2), pp. 216 - 226 (2006)
Journal Article
Schmidt, J. K.; König, B.; Reichl, U.: Characterization of a Three Bacteria Mixed Culture in a Chemostat: Evaluation and Application of a Quantitative Terminal-Restriction Fragment Polymorphism (T-RFLP) Analysis for Absolute and Species Specific Cell Enumeration. Biotechnology and Bioengineering 96 (4), pp. 738 - 756 (2006)
2005
Journal Article
Genzel, Y.; Ritter, J. B.; König, S.; Alt, R.; Reichl, U.: Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells. Biotechnology Progress 21 (1), pp. 58 - 69 (2005)
Journal Article
Möhler, L.; Flockerzi, D.; Sann, H.; Reichl, U.: Mathematical Model of Influenza A Virus Production in Large-Scale Microcarrier Culture. Biotechnology and Bioengineering 90 (1), pp. 46 - 58 (2005)
Journal Article
Nayak, D. P.; Lehmann, S.; Reichl, U.: Downstream processing of MDCK cell-derived equine influenza virus. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 823 (2), pp. 75 - 81 (2005)
Journal Article
Wickramasinghe, S. R.; Kalbfuss, B.; Zimmermann, A.; Thom, V.; Reichl, U.: Tangential flow microfiltration and ultrafiltration for human influenza A virus concentration and purification. Biotechnology and Bioengineering 92 (2), pp. 199 - 208 (2005)
2004
Journal Article
Genzel, Y.; Behrendt, I.; König, S.; Sann, H.; Reichl, U.: Metabolism of MDCK Cells during cell growth and influenza virus production in large-scale microcarrier culture. Vaccine 22, pp. 2202 - 2208 (2004)
Journal Article
Genzel, Y.; König, S.; Reichl, U.: Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detection. Analytical Biochemistry 335, pp. 119 - 125 (2004)
Journal Article
Genzel, Y.; Reichl, U.: Bioprozesstechnik und Impfstoff-Forschung an der Elbe. Bioforum 27 (5), pp. 44 - 46 (2004)
Journal Article
Nayak, D. P.; Reichl, U.: Neuraminidase activity assays for monitoring MDCK cell culture derived influenza virus. Journal of Virological Methods 122, pp. 9 - 15 (2004)
Journal Article
Sidorenko, Y.; Reichl, U.: A Structured Model of Influenza Virus Replication in MDCK Cells. Biotechnology and Bioengineering 88 (1), pp. 1 - 14 (2004)
2003
Journal Article
Tallarek, U.; Rapp, E.; Sann, H.; Reichl, U.; Seidel-Morgenstern, A.: Quantitative study of electrokinetic transport in porous media by confocal laser scanning microscopy. Langmuir 19, pp. 4527 - 4531 (2003)
2002
Journal Article
Genzel, Y.; Reichl, U.: Analysis of cell growth, virus replication and medium composition in equine influenza vaccine production. Chemie-Ingenieur-Technik 74 (5), pp. 673 - 674 (2002)
Journal Article
Trotha, R.; Reichl, U.; Thies, F. L.; Sperling, D.; Koenig, W.; Koenig, B.: Adaption of a fragment analysis technique to an automated high- throughput multicapillary electrophoresis device for the precise qualitative and quantitative characterization of microbial communities. Electrophoresis 23 (7-8), pp. 1070 - 1079 (2002)
2001
Journal Article
Kremling, A.; Bettenbrock, K.; Stelling, J.; Reichl, U.; Gilles, E. D.: Systemorientierte Bioprozesstechnik: interdisziplinäre Forschung in Biologie, System- und Computerwissenschaften. Magdeburger Wissenschaftsjournal 6 (1/2), pp. 29 - 36 (2001)

Book (2)

2021
Book
Rapp, E.; Reichl, U. (Eds.): Advances in Glycobiotechnology. Springer, Cham, Switzerland (2021), 463 pp.
2014
Book
Benner, P.; Findeisen, R.; Flockerzi, D.; Reichl, U.; Sundmacher, K. (Eds.): Large-Scale Networks in Engineering and Life Sciences. Springer International Publishing, Switzerland (2014), 388 pp.

Book Chapter (19)

2023
Book Chapter
Göbel, S.; Pelz, L.; Reichl, U.; Genzel, Y.: Upstream processing for viral vaccines - Process intensification. In: Bioprocessing of Viral Vaccines, 1st edition Ed., pp. 137 - 174 (Eds. Kamen, A.; Cervera, L.). CRC Press, Boca Raton (2023)
Book Chapter
Pelz, L.; Göbel, S.; Jaen , K.; Reichl, U.; Genzel, Y.: Upstream processing for viral vaccines – General aspects. In: Bioprocessing of Viral Vaccines, 1st edition Ed., pp. 79 - 136 (Eds. Kamen , A.; Cervera , L.). CRC Press, Boca Raton (2023)
2021
Book Chapter
Alagesan, K.; Hoffmann, M.; Rapp, E.; Kolarich, D.: Glycoproteomics Technologies in Glycobiotechnology. In: Advances in Glycobiotechnology, pp. 413 - 434 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
Book Chapter
Butler, M.; Reichl, U.: Animal Cell Expression Systems. In: Advances in Glycobiotechnology, pp. 1 - 36 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
Book Chapter
Cajic, S.; Hennig, R.; Burock, R.; Rapp, E.: Capillary (Gel) Electrophoresis-Based Methods for Immunoglobulin (G) Glycosylation Analysis. In: Antibody Glycosylation, pp. 137 - 172 (Ed. Pezer, M.). Springer, Cham, Switzerland (2021)
Book Chapter
Pralow, A.; Cajic, S.; Alagesan, K.; Kolarich, D.; Rapp, E.: State-of-the-Art Glycomics Technologies in Glycobiotechnology. In: Advances in Glycobiotechnology, pp. 379 - 411 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
Book Chapter
Rexer, T.; Laaf, D.; Gottschalk, J.; Frohnmeyer, H.; Rapp, E.; Elling, L.: Enzymatic Synthesis of Glycans and Glycoconjugates. In: Advances in Glycobiotechnology, pp. 231 - 280 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
2020
Book Chapter
Bürgin, T.; Coronel, J.; Hagens, G.; Keebler, M. V.; Genzel, Y.; Reichl, U.; Anderlei, T.: Orbitally Shaken Single-Use Bioreactor for Animal Cell Cultivation: Fed-Batch and Perfusion Mode. In: Animal Cell Biotechnology, pp. 105 - 123 (Ed. Pörtner, R.). Humana, New York (2020)
Book Chapter
Nikolay, A.; Bissinger, T.; Gränicher, G.; Wu, Y.; Genzel, Y.; Reichl, U.: Perfusion Control for High Cell Density Cultivation and Viral Vaccine Production. In: Animal Cell Biotechnology, pp. 141 - 168 (Ed. Pörtner, R.). Humana, New York (2020)
2019
Book Chapter
Hoffmann, D.; Leber, J.; Loewe, D.; Lothert, K.; Oppermann, T.; Zitzmann, J.; Weidner, T.; Salzig, D.; Wolff, M. W.; Czermak, P.: Purification of New Biologicals Using Membrane-Based Processes. In: Current Trends and Future Developments on (Bio-) Membranes, pp. 123 - 150 (Eds. Basile, A.; Charcosset, C.). Elsevier (2019)
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