IMPRS Publications

Journal Article

Koch, S.; Kohrs, F.; Lahmann, P.; Bissinger, T.; Wendschuh, S.; Benndorf, D.; Reichl, U.; Klamt, S.: RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion. PLoS Computational Biology 15 (2), e1006759 (2019)

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Journal Article

Kunde, C.; Keßler, T.; Linke, S.; McBride, K.; Sundmacher, K.; Kienle, A.: Surrogate Modeling for Liquid–Liquid Equilibria Using a Parameterization of the Binodal Curve. Processes (7), 753 (2019)

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Journal Article

Liesche, G.; Sundmacher, K.: Productivity versus product quality: Exploring the limits of autothermal microchannel reactors in methane steam reforming. Chemical Engineering Journal (ISCRE 25 Special Issue) 377, 120048 (2019)

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Journal Article

Liesche, G.; Sundmacher, K.: Radiation-based model reduction for the optimization of high temperature tube bundle reactors: Synthesis of hydrogen cyanide. Computers and Chemical Engineering 127, pp. 186 - 199 (2019)

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Journal Article

Lindhorst, H.; Lucia, S.; Findeisen, R.; Waldherr, S.: Modeling Enzyme Controlled Metabolic Networks in Rapidly Changing Environments by Robust Optimization. IEEE Control Systems Letters 3 (2), pp. 248 - 253 (2019)

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Journal Article

Rätze, K.; Jokiel, M.; Kaiser , N. M.; Sundmacher, K.: Cyclic Operation of a Semi-Batch Reactor for the Hydroformylation of Long-Chain Olefins and Integration in a Continuous Production Process. Chemical Engineering Journal (ISCRE 25 Special Issue) 377, 120453 (2019)

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Journal Article

Reeh, H.; Rudolph, N.; Billing, U.; Christen, H.; Streif, S.; Bullinger, E.; Schliemann-Bullinger, M.; Findeisen, R.; Schaper, F.; Huber, H. J. et al.; Dittrich, A.: Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling. Cell Communication and Signaling 17, 46 (2019)

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Journal Article

Schack, D.; Liesche, G.; Sundmacher, K.: Simultaneous Heat and Mass Flow Optimization of a Distillation Column Applying the FluxMax Approach. Chemical Engineering Transactions 76, pp. 337 - 342 (2019)

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Journal Article

Temmel, E.; Eicke, M.; Cascella, F.; Seidel-Morgenstern, A.; Lorenz, H.: Resolution of Racemic Guaifenesin Applying a Coupled Preferential Crystallization-Selective Dissolution Process: Rational Process Development. Crystal Growth & Design 19, pp. 3148 - 3157 (2019)

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Journal Article

Uebbing, J.; Rihko-Struckmann, L.; Sundmacher, K.: Exergetic assessment of CO₂ methanation processes for the chemical storage of renewable energies. Applied Energy 233–234, pp. 271 - 282 (2019)

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Journal Article

Vorhauer, N.; Altaf, H.; Tsotsas, E.; Vidaković-Koch, T.: Pore Network Simulation of Gas-Liquid Distribution in Porous Transport Layers. Processes 7 (9), 558 (2019)

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Journal Article

Weinrich, S.; Koch, S.; Bonk, F.; Popp, D.; Benndorf, D.; Klamt, S.; Centler, F.: Augmenting Biogas Process Modeling by Resolving Intracellular Metabolic Activity. Frontiers in Microbiology 10, 1095 (2019)

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Journal Article

Xie, X.; Schenkendorf, R.: Robust Process Design in Pharmaceutical Manufacturing under Batch-to-Batch Variation. Processes 7 (8), 509 (2019)

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Journal Article

Xie, X.; Schenkendorf, R.: Robust optimization of a pharmaceutical freeze-drying process under non-Gaussian parameter uncertainties. Chemical Engineering Science 207, pp. 805 - 819 (2019)

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Journal Article

Xie, X.; Schenkendorf, R.: Stochastic back-off-based robust process design for continuous crystallization of ibuprofen. Computers & Chemical Engineering 124, pp. 80 - 92 (2019)

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Journal Article

Xie, X.; Schenkendorf, R.; Krewer, U.: The Effect of Correlated Kinetic Parameters on (Bio)Chemical Reaction Networks. Chemie Ingenieur Technik 91 (5), pp. 632 - 636 (2019)

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Journal Article

Xie, X.; Schenkendorf, R.; Krewer, U.: Efficient sensitivity analysis and interpretation of parameter correlations in chemical engineering. Reliability Engineering & System Safety 187, pp. 159 - 173 (2019)

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2018

Journal Article

Aydin, E.; Bonvin, D.; Sundmacher, K.: Computationally efficient NMPC for batch and semi-batch processes using parsimonious input parameterization. Journal of Process Control 66, pp. 12 - 22 (2018)

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Journal Article

Aydin, E.; Bonvin, D.; Sundmacher, K.: Toward Fast Dynamic Optimization: An Indirect Algorithm That Uses Parsimonious Input Parameterization. Industrial & Engineering Chemistry Research 57, pp. 10038 - 10048 (2018)

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Journal Article

Bechtel, S.; Vidaković-Koch, T.; Sundmacher, K.: Novel process for the exergetically efficient recycling of chlorine by gas phase electrolysis of hydrogen chloride. Chemical Engineering Journal 346, pp. 535 - 548 (2018)

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Journal Article

Benner, P.; Goyal, P. K.; Gugercin, S.: H₂-Quasi-Optimal Model Order Reduction for Quadratic-Bilinear Control Systems. SIAM Journal on Matrix Analysis and Applications 39 (2), pp. 983 - 1032 (2018)

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Journal Article

Benner, P.; Trautwein, C.: A Linear Quadratic Control Problem for the Stochastic Heat Equation Driven by Q-Wiener Processes. Journal of Mathematical Analysis and Applications 457 (1), pp. 776 - 802 (2018)

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Journal Article

Cheema, I. I.; Krewer, U.: Operating envelope of Haber–Bosch process design for power-to-ammonia. RSC Advances 2018 (8), pp. 34926 - 34936 (2018)

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supplementary-material

Journal Article

Chi, C.; Abdelsamie, A.; Thévenin, D.: Direct Numerical Simulations of Hotspot-induced Ignition in Homogeneous Hydrogen-air Pre-mixtures and Ignition Spot Tracking. Flow, Turbulence and Combustion 101 (1), pp. 103 - 121 (2018)

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Journal Article

Emenike, V. N.; Schenkendorf, R.; Krewer, U.: A systematic reactor design approach for the synthesis of active pharmaceutical ingredients. European Journal of Pharmaceutics and Biopharmaceutics 126, pp. 75 - 88 (2018)

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Journal Article

Emenike, V. N.; Schenkendorf, R.; Krewer, U.: Model-based optimization of biopharmaceutical manufacturing in Pichia pastoris based on dynamic flux balance analysis. Computers & Chemical Engineering 118, pp. 1 - 13 (2018)

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Journal Article

Fechtner, M.; Kienle, A.: Efficient simulation and equilibrium theory for adsorption processes with implicit adsorption isotherms – Ideal adsorbed solution theory. Chemical Engineering Science 177, pp. 284 - 292 (2018)

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Journal Article

Haeseler, F. v.; Rudolph, N.; Findeisen, R.; Huber, H. J.: Parameter Estimation for Signal Transduction Networks from Experimental Time Series Using Picard Iteration. IFAC-PapersOnLine 51, pp. 191 - 196 (2018)

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Journal Article

Harder, B.-J.; Bettenbrock, K.; Klamt, S.: Temperature-dependent dynamic control of the TCA cycle increases volumetric productivity of itaconic acid production by Escherichia coli. Biotechnology and Bioengineering 115 (1), pp. 156 - 164 (2018)

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Journal Article

Hosseini, S. A.; Darabiha, N.; Thévenin, D.: Mass-conserving advection–diffusion Lattice Boltzmann model for multi-species reacting flows. Physica A: Statistical Mechanics and its Applications 499, pp. 40 - 57 (2018)

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Journal Article

Jabarivelisdeh, B.; Waldherr, S.: Optimization of bioprocess productivity based on metabolic-genetic network models with bilevel dynamic programming. Biotechnology and Bioengineering 115 (7), pp. 1829 - 1841 (2018)

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Journal Article

Jongsma, H.-J.; Mlinarić, P.; Grundel, S.; Benner, P.; Trentelman, H. L.: Model Reduction of Linear Multi-Agent Systems by Clustering and with H₂- and H_∞-Error Bounds. Mathematics of Control, Signals, and Systems 30 (1), 6, 38 pages (2018)

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Journal Article

Liesche, G.; Sundmacher, K.: Identification of Key Transport Phenomena in High-Temperature Reactors: Flow and Heat Transfer Characteristics. Industrial & Engineering Chemistry Research 57 (46), pp. 15884 - 15897 (2018)

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Journal Article

Lin, N.; Xie, X.; Schenkendorf, R.; Krewer, U.: Efficient Global Sensitivity Analysis of 3D Multiphysics Model for Li-Ion Batteries. Journal of The Electrochemical Society 165 (7), pp. A1169 - A1183 (2018)

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Journal Article

Rexer, T.; Schildbach, A.; Klapproth, J.; Schierhorn, A.; Mahour, R.; Pietzsch, M.; Rapp, E.; Reichl, U.: One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides. Biotechnology and Bioengineering 115 (1), pp. 192 - 205 (2018)

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Journal Article

Rudolph, N.; Andonov, P.; Huber, H. J.; Findeisen, R.: Model-supported Patient Stratification Using Set-based Estimation Methods. IFAC-PapersOnLine 51, pp. 892 - 897 (2018)

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Journal Article

Schenkendorf, R.; Xie, X.; Rehbein, M.; Scholl, S.; Krewer, U.: The impact of global sensitivities and design measures in model-based optimal experimental design. Processes 6 (4), 27 (2018)

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Journal Article

Tetschke, M.; Lilienthal, P.; Pottgiesser, T.; Fischer, T.; Schalk, E.; Sager, S.: Mathematical Modeling of RBC Count Dynamics after Blood Loss. Processes 6 (9), 157 (2018)

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Journal Article

Triemer, S.; Gilmore, K.; Vu, T. G.; Seeberger, P. H.; Seidel-Morgenstern, A.: Literally green chemical synthesis of artemisinin from plant extracts. Angewandte Chemie International Edition 57 (19), pp. 5525 - 5528 (2018)

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Journal Article

Triemer, S.; Gilmore, K.; Vu, T. G.; Seeberger, P. H.; Seidel-Morgenstern, A.: Wirklich grüne Synthese von Artemisinin aus Pflanzenextrakt. Angewandte Chemie 130, pp. 5623 - 5626 (2018)

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Journal Article

Xie, X.; Schenkendorf, R.; Krewer, U.: Toward a Comprehensive and Efficient Robust Optimization Framework for (Bio)chemical Processes. Processes 6 (10), 183 (2018)

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Journal Article

Zhao, W.; Hon, Y.-C.; Stoll, M.: Localized radial basis functions-based pseudo-spectral method (LRBF-PSM) for nonlocal diffusion problems. Computers & Mathematics with Applications 75 (5), pp. 1685 - 1704 (2018)

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Journal Article

Zhao, W.; Hon, Y. C.; Stoll, M.: Numerical Simulations of Nonlocal Phase-Field and Hyperbolic Nonlocal Phase-Field Models via Localized Radial Basis Functions-Based Pseudo-Spectral Method (LRBF-PSM). Applied Mathematics and Computation 337, pp. 514 - 534 (2018)

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2017

Journal Article

Ahmad, M. I.; Benner, P.; Goyal, P. K.: Krylov Subspace-Based Model Reduction for a Class of Bilinear Descriptor Systems. Journal of Computational and Applied Mathematics 315, pp. 303 - 318 (2017)

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Journal Article

Ahmad, M. I.; Benner, P.; Goyal, P. K.; Heiland, J.: Moment-Matching Based Model Reduction for Navier–Stokes Type Quadratic-Bilinear Descriptor Systems. Zeitschrift für Angewandte Mathematik und Mechanik 97 (10), pp. 1252 - 1267 (2017)

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Journal Article

Aydin, E.; Bonvin, D.; Sundmacher, K.: Dynamic Optimization of Constrained Semi-Batch Processes using Pontryagin's Minimum Principle - An effective Quasi-Newton Method. Computers and Chemical Engineering 99, pp. 135 - 144 (2017)

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Journal Article

Bremer, J.; Goyal, P. K.; Feng, L.; Benner, P.; Sundmacher, K.: POD-DEIM for Efficient Reduction of a Dynamic 2D Catalytic Reactor Model. Computers & Chemical Engineering 106, pp. 777 - 784 (2017)

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Journal Article

Bremer, J.; Rätze, K.; Sundmacher, K.: CO₂ Methanation: Optimal Start-Up Control of a Fixed-Bed Reactor for Power-To-Gas Applications. AIChE-Journal 63 (1), pp. 23 - 31 (2017)

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Journal Article

Chi, C.; Janiga, G.; Abdelsamie, A.; Zähringer, K.; Turányi, T.: DNS Study of the Optimal Chemical Markers for Heat Release in Syngas Flames. Flow, Turbulence and Combustion 98 (4), pp. 117 - 1132 (2017)

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