Publications BPE group
Journal Article (7)
1.
Journal Article
124 (2), pp. 347 - 362 (2006)
Production of hantavirus Puumala nucleocapsid protein in Saccharomyces cerevisiae for vaccine and diagnostics. Journal of Biotechnology 2.
Journal Article
24, pp. 3261 - 3272 (2006)
Serum-free influenza virus production avoiding washing steps & medium exchange in large-scale microcarrier culture. Vaccine 3.
Journal Article
24 (35-36), pp. 6074 - 6087 (2006)
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media. Vaccine 4.
Journal Article
53 (4), pp. 556 - 584 (2006)
Coexistence in the Chemostat as a result of metabolic by-products. Journal of mathematical biology 5.
Journal Article
10 (4), pp. 18 - 20 (2006)
Preparative Size-Exclusion Chromatography. GIT Laboratory Journal Europe 6.
Journal Article
843 (2), pp. 216 - 226 (2006)
High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in culture. Journal of Chromatography B 7.
Journal Article
96 (4), pp. 738 - 756 (2006)
Characterization of a Three Bacteria Mixed Culture in a Chemostat: Evaluation and Application of a Quantitative Terminal-Restriction Fragment Polymorphism (T-RFLP) Analysis for Absolute and Species Specific Cell Enumeration. Biotechnology and Bioengineering Meeting Abstract (2)
8.
Meeting Abstract
Metabolic Flux Analysis of MDCK Cells in Glutamine-Containing and Glutamine-Free Culture Media. In Metabolic Engineering VI: Program, p. 102. Metabolic Engineering IV, Noordwijkerhout, The Netherlands, October 01, 2006 - October 05, 2006. (2006)
9.
Meeting Abstract
Stochastic Population Balance Modeling of Influenza Virus replication in a Vaccine Production Process. In Conference Proceedings / AIChE annual meeting 2006, p. 622f. AIChE annual meeting 2006, San Francisco, USA, November 12, 2006 - November 17, 2006. (2006)
Talk (20)
10.
Talk
Characterization and analytical issues on an influenza A virus production process. Vaccines : Quality control, scale-up and manufacture, Hamburg, Germany (2006)
11.
Talk
Production of vaccines based on animal cell technology. Production of Biopharmaceuticals in Animal Cell Cultures, Rio de Janeiro, Brazil (2006)
12.
Talk
Limits and benefits of the interpretation of extracellular metabolite data in mammalian cell culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
13.
Talk
Neue Zellsubstrate und Einfluss von Medien und Prozessführung in der Impfstoffproduktion. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
14.
Talk
High Cell Density Microcarrier Process in a Wave Bioreactor for the Production of Influenza A Virus. Vaccine Technology, Puerto Vallarta, Mexiko (2006)
15.
Talk
Maximizing productivity in size-exclusion chromatography of influenza virus: A modelling approach. ESBES 6 : 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (2006)
16.
Talk
Konzentrierung und Aufreinigung von Influenza Viren mittels Ionenaustauscher-Membranen. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
17.
Talk
A generic purification scheme for the production of human influenza vaccines derived from serum-free mammalian cell culture. Vaccine Technology, Puerto Vallarta, Mexico (2006)
18.
Talk
Chromatography-based purification of influenza A virus for the production of human whole-virion vaccines. ISPPP 2006 : 26th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Innsbruck, Austria (2006)
19.
Talk
MDCK Cell Derived Influenza Vaccines: Aspects of Up- and Downstream Processing. Meeting Academy of Science, Sofia, Bulgarien (2006)
20.
Talk
Dynamics of Influenza Virus Replication in Mammalian Cell Culture. CCEX Workshop, Vancouver, Canada (2006)
21.
Talk
MDCK Cell derived Influenza Vaccines: Aspects of Modeling and Experimental Design in Upstream Processing. Meeting at Sanof Pasteur, Toronto, Canada (2006)
22.
Talk
Biological Fundamentals, Models and Technologies for Vaccine Production. Perspectives of Research - Identification and Implementation of Research Topics by Organizations : Ringberg-Symposium Mai 2006, Kreuth, Germany (2006)
23.
Talk
Mathematical Models for Mammalian Cell Growth and Virus Replication for an Influenza Vaccine Production Process. Technische Universität Berlin : Meeting, Berlin, Germany (2006)
24.
Talk
Monitoring Energy Metabolism: The Challenge of Intracellular Metabolite Analysis of Mammalian Cells in Culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
25.
Talk
Mammalian cell culture for influenza vaccine production: physiology during cell growth and virus propagation phase. GVC/DECHEMA-Jahrestagungen 2006 mit 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
26.
Talk
Metabolic and Isotopic Instationary Experiments: A Simulative Study. Metabolic Engineering VI, Noordwijkerhout, The Netherlands (2006)
27.
Talk
Experiments at Metabolic and Isotopic Instationary State: An Exploratory study. Metabolic Engineering VI : From recDNA Towards Engineering Biological Systems, Noordwijkerhout, Netherlands (2006)
28.
Talk
Downstream Processes and Glycan Characterization of MDCK-Cell Derived Influenza Virus. BioProcess Technology - Asia, Singapore (2006)
29.
Talk
Downstream Process of Influenza Viruses. European BioPharm Scale-Up Congress 2006, Geneva, Switzerland (2006)
Poster (10)
30.
Poster
Correlation of specific oxygen uptake rates and cell cycle duration of adherent mammalian cells in a large-scale microcarrier system. 6th European Symposium on Biochemical Engineering Science : ESBES 6, Salzburg, Austria (2006)
31.
Poster
Perfusion system in high-density cell culture for higher yields in vaccine production. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
32.
Poster
Lectin-affinity purification of cell culture derived human Influenza A viruses. Vaccine Technology 2006, Puerto Vallarta, Mexico (2006)
33.
Poster
Lektin-Affinitätschromatographie zur Aufreinigung humaner Influenza Viren. GVC/DECHEMA-Jahrestagungen 2006, Wiesbaden, Germany (2006)
34.
Poster
Lectin-affinity purification of cell culture derived human Influenza A viruses. ESBES 6 : 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (2006)
35.
Poster
Die Herausforderung der Analyse von intrazellulären Metaboliten in Säugerzellen. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
36.
Poster
Monitoring Energy Metabolism: The Challenge of Intracellular Metabolite Analysis of Mammalian Cells in Culture. Cell Culture Engineering X, Whistler, Canada (2006)
37.
Poster
Glycosylation of Influenza A Virus Hemagglutinin. 6th European Symposium on Biochemical Engineering Science (ESBES), Salzburg, Austria (2006)
38.
Poster
Analysis of cellular metabolism and influenza viral replication of three human cell lines as candidates for proteomics. ESBES 6 : 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (2006)
39.
Poster
Real-Time PCR for quantitative analysis of human influenza A virus in infected mammalian cells. GVC/DECHEMA-Jahrestagungen 2006, Wiesbaden, Germany (2006)
Thesis - PhD (1)
40.
Thesis - PhD
Segregierte mathematische Modelle zum Wachstum adhärenter tierischer Zellen (MDCK) und zur Influenza Virus Replikation. Dissertation, Shaker, Aachen (2006)
Thesis - Diploma (2)
41.
Thesis - Diploma
Quantification of Influenza Virus Hemagglutinin (HA) by Reversed Phase - High pressure Liquid Chromatography (RP-HPLC) method. Diploma (2006)
42.
Thesis - Diploma
Development of a Lectin-Affinity Chromatography for the Downstream Processing of Influenza A Virus Vaccines. Diploma (2006)