Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203

Contact Person

Annegret Frauendienst
Phone: +49 391 6110 200
Fax: +49 391 6110 203

Group Page

Publications

Publications BPE group

Journal Article (18)

  1. 2014
    Benndorf, D.; Reichl, U.: Proteomics in environmental and technical microbiology. Engineering in Life Sciences 14 (1), pp. 27 - 46 (2014)
  2. Bensch, G.; Rüger, M.; Wassermann, M.; Weinholz, S.; Reichl, U.; Cordes, C.: Flow cytometric viability assessment of lactic acid bacteria starter cultures produced by fluidized bed drying. Applied Microbiology and Biotechnology 98 (11), pp. 4897 - 4909 (2014)
  3. Bensmann, A.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Reichl, U.; Sundmacher, K.: Biological methanation of hydrogen within biogas plants: A model-based feasibility study. Applied Energy 134, pp. 413 - 425 (2014)
  4. Diba, M.; Goudouri, O.-M.; Tapia, F.; Boccaccini, A. R.: Magnesium-containing bioactive polycrystalline silicate-based ceramics and glass-ceramics for biomedical applications. Current Opinion in solid state & materials science 18 (3), pp. 147 - 167 (2014)
  5. Frensing, T.; Pflugmacher, A.; Bachmann, M.; Peschel, B.; Reichl, U.: Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production. Applied Microbiology and Biotechnology 98 (21), pp. 8999 - 9008 (2014)
  6. Genzel, Y.; Vogel, T.; Buck, J.; Behrendt, I.; Vazquez-Ramirez, D.; Schiedner, G.; Jordan, I.; Reichl, U.: High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells. Vaccine 32 (24), pp. 2770 - 2781 (2014)
  7. Huffman, J. E.; Pucic-Bakovic, M.; Klaric, L.; Hennig, R.; Selman, M. H.J.; Vuckovic, F.; Novokmet, M.; Kristic, J.; Borowiak, M.; Muth, T. et al.; Polasek, O.; Razdorov, G.; Gornik, O.; Plomp, R.; Theodorarou, E.; Wright, A. F.; Rudan, I.; Hayward, C.; Campbell, H.; Deelder, A. M.; Reichl, U.; Aulchenko, Y. S.; Rapp, E.; Wuhrer , M.; Lauc , G.: Comparative Performance of Four Methods for High-throughput Glycosylation Analysis of Immunoglobulin G in Genetic and Epidemiological Research. Molecular and Cellular Proteomics 13 (6), pp. 1598 - 1610 (2014)
  8. Kohrs, F.; Heyer, R.; Magnussen, A.; Benndorf, D.; Muth, T.; Behne, A.; Rapp, E.; Kausmann, R.; Heiermann, M.; Klocke, M.: Sample prefractionation with liquid isoelectric focusing enables in depth microbial metaproteome analysis of mesophilic and thermophilic biogas plants. Anaerobe 29, pp. 59 - 67 (2014)
  9. Lohr, V.; Hädicke, O.; Genzel, Y.; Jordan, I.; Buentemeyer, H.; Klamt, S.; Reichl, U.: The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis. BMC Biotechnology 14, p. 72 (2014)
  10. Muth, T.; Weilnböck, L.; Rapp, E.; Huber, C. G.; Martens, L.; Vaudel, M.; Barnsnes, H.: DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra. Journal of Proteome Research 13 (2), pp. 1143 - 1146 (2014)
  11. Rath, A.; Rehberg, M.; Janke, R.; Genzel, Y.; Scholz, S.; Noll, T.; Rose, T.; Sandig, V.; Reichl, U.: The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells. Journal of Biotechnology 178, pp. 43 - 53 (2014)
  12. Rehberg, M.; Rath, A.; Ritter, J.; Genzel, Y.; Reichl, U.: Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media. Applied Microbiology and Biotechnology 98 (1), pp. 385 - 397 (2014)
  13. Rehberg, M.; Ritter, J.; Reichl, U.: Glycolysis Is Governed by Growth Regime and Simple Enzyme Regulation in Adherent MDCK Cells. PLoS Computational Biology 10 (10), p. e1003885 (2014)
  14. Rüger, M.; Ackermann, M.; Reichl, U.: Species-specific viability analysis of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus in mixed culture by flow cytometry. BMC Microbiology 14, p. 56 - 56 (2014)
  15. Tapia, F.; Vogel, T.; Genzel, Y.; Behrendt, I.; Hirschel, M.; Gangemi, J. D.; Reichl, U.: Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor. Vaccine 32 (8), pp. 1003 - 1011 (2014)
  16. Wang, W.; Wolff, M. W.; Reichl, U.; Sundmacher, K.: Avidity of influenza virus: Model-based identification of adsorption kinetics from surface plasmon resonance experiments. Journal of Chromatography A 1326, pp. 125 - 129 (2014)
  17. Weigel, T.; Solomaier, T.; Peuker, A.; Pathapati, T.; Wolff, M. W.; Reichl, U.: A flow-through chromatography process for influenza A and B virus purification. Journal of Virological Methods 207, pp. 45 - 53 (2014)
  18. York, W.S.; Agravat, S.; Aoki-Kinoshita, K.F.; Mcbride, R.; Campell, F.; Castello, C.E.; Dell, A.; Feizi, T.; Haslam, S.M.; Karlsson, N. et al.; Khoo, K.-H.; Kolarich, D.; Liu, Y.; Novotny, M.; Packer, N.H.; Paulson, J.C.; Rapp, E.; Ranzinger, R.; Rudd, P.M.; Smith, D.F.; Struwe, W.B.; Tiemeyer, M.; Wells, L.; Zaia, J.; Kettner, C.: MIRAGE: The minimum information required for a glycomics experiment. Glycobiology 24 (5), pp. 402 - 406 (2014)

Book (1)

  1. Benner, P.; Findeisen, R.; Flockerzi, D.; Reichl, U.; Sundmacher, K. (Eds.): Large-Scale Networks in Engineering and Life Sciences. Springer International Publishing, Switzerland (2014), 388 pp.

Book Chapter (2)

  1. Genzel, Y.; Rödig, J.; Rapp, E.; Reichl, U.: Vaccine production: Upstream processing with adherent or suspension cell lines. In: Animal Cell Biotechnology: Methods and Protocols, pp. 371 - 393 (Ed. Pörtner, R.). HUMANA Press Inc., New York (2014)
  2. Merten, O.-W.; Bakker, W. A.M.; Vorlop, J.; Reiter, M.; Visnovsky, G.; Jäger, V.; Merabishvili, M.; Reichl, U.: Virus Production Under Suspension Conditions. In: Industrial Scale Suspension Culture of Living Cells, pp. 503 - 554. Wiley Blackwell, Weinheim (2014)

Meeting Abstract (5)

  1. Fernandes, P.; Castro, R.; Laske, T.; Genzel, Y.; Kremer, E.; Alves, P.; Coroadinha, A.: The impact of MDCK cell source on the production of influenza and canine adenovirus. In: New Biotechnology: Abstracts of the 16th European Congress on Biotechnology, Vol. 31 Supplement, p. S180. (2014)
  2. Müller, C.; Hoffmann, D.; Cajic, S.; Hennig, R.; Sgodda, M.; van Diepen, L.; Weissmann, R.; Steinemann, D.; Rapp, E.; Kuss, A. et al.; Cantz, T.; Schambach, A.; Büttner, F.: Functional characterization of PMM2-CDG patient-derived iPSCs. In: GLYCOBIOLOGY, p. 1101 - 1101. (2014)
  3. Müller, C.; Hoffmann, D.; Cajic, S.; Hennig, R.; Sgodda, M.; van Diepen, L.; Weissmann, R.; Steinemann, D.; Rapp, E.; Kuss, A. et al.; Cantz, T.; Schambach, A.; Buettner, F.: Functional characterization of PMM2-CDG patient-derived iPSCs. In: Glycobiology, Vol. 24, p. 1101 - 1101. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, Hawaii, USA, November 16, 2014 - November 19, 2014. IRL Press at Oxford University Press, Oxford (2014)
  4. Müller, C.; Hoffmann, D.; Cajic, S.; Hennig, R.; Sgodda, M.; van Diepen, L.; Weissmann, R.; Steinemann, D.; Rapp, E.; Kuss, A. et al.; Cantz, T.; Schambach, A.; Buettner, F. F. R.: Molecular characterization of hiPSCs from a PMM2-CDG patient revealed aberrant glycosylation. In: Glycobiology, Vol. 24, pp. 1176 - 1177. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, Hawaii, USA, November 16, 2014 - November 19, 2014. IRL Press at Oxford University Press, Oxford (2014)
  5. Pucic-Bakovic, M.; Huffman, J. E.; Klaric, L.; Hennig, R.; Selman, M. H. J.; Aulchenko, Y. S.; Rapp, E.; Wuhrer , M.; Lauc, G.: Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research. In: Glycobiology, Vol. 24, p. 1160 - 1160. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, Hawaii, USA, November 16, 2014 - November 19, 2014. IRL Press at Oxford University Press, Oxford (2014)

Talk (15)

  1. Benndorf, D.: Metaproteomics for process monitoring of anaerobic digesters. 2nd International Conference on Biogas Microbiology, Uppsala, Sweden (2014)
  2. Benndorf, D.: Metaproteome analysis indicates for the presence of (anaerobic) fungi and bacteriophages in anaerobic digesters. Symposium Novel Anaerobes, Wageningen, The Netherlands (2014)
  3. Bensmann, B.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Sundmacher, K.: Methanation of renewable hydrogen within biogas reactors? A process systems engineering approac. CHISA 2014, Prague/Czech Republic (2014)
  4. Fischer, L. M.: Modeling and simulation of the purification of cell culture-derived influenza virus via continuous size exclusion chromatography. SPICA 2014-15th International Symposium on Preparative and Industrial Chromatography and Allied Techniques, Basel, Switzerland (2014)
  5. Genzel, Y.; Reichl, U.: New cell substrates for virus and viral vector production. ISBIOTECH 4th Spring Meeting, Washington, USA (2014)
  6. Genzel, Y.: Research towards continuous viral vaccine manufacturing. BioTalk-Biological Manufacturing Excellence 2014, Berlin, Germany (2014)
  7. Heldt, S.; Frensing, T.; Reichl, U.: The multiscale nature of influenza A virus infection and its implications for modeling antiviral therapy. The Joint Annual Meeting of the Japanese Society for Mathematical Biology and the Society for Mathematical Biology, Osaka, Japan (2014)
  8. Heyer, R.; Kohrs, F.; Benndorf, D.; Rapp, E.; Reichl, U.: Analysing the microbial population structure and metabolic function by metaproteome analysis. Biogas Science 2014 (International Conference on Anaerobic Digestion), Wien, Austria (2014)
  9. Hoffmann, M.: Human Blood Plasma O-Glycoproteomics. Bruker Anwendertreffen 2014, Berlin, Germany (2014)
  10. Laske, T.: Mathematical modeling of virus-host cell interactions during influenza virus replication supports cell line development for vaccine production. Workshop on Virus Dynamics and Evolution des Centre De Recerca Matemàtica (CRM), Bellaterra, Spain (2014)
  11. Muth, T.; Behne, A.; Heyer, R.; Kohrs, F.; Benndorf, D.; Hoffmann, M.; Reichl, U.; Martens, L.: MetaProteomeAnalyzer – a software suite for the functional and taxonomic characterization of (meta)proteome data. 12th Austrian Proteomic Research Symposium, Salzburg, Austria (2014)
  12. Rapp, E.; Hennig, R.; Muth, T.; Kottler, R.; Cajic, S.; Reichl, U.: HIGH PERFORMANCE GLYCOANALYSIS TO IMPROVE BIOLOGICS DEVELOPMENT. Cell Culture Engineering XIV (CCE) 2014, Quebec (Canada) (2014)
  13. Reichl, U.: High-Throughput Glycoanalysis for Characterization of Proteins and Sugars in Research and Industry. Sitzung der Technikwissenschaftlichen Klasse an der Sächsischen Akademie der Wissenschaften zu Leipzig, Leipzig, Germany (2014)
  14. Serve, A.; Kluge, S.: Probenvorbereitung zur qualitativen Protein- und Lipidanalytik: Anwendung in der Inprozess-Kontrolle der Virusproduktion. 21. Arbeitstagung "Mikromethoden in der Proteinchemie", Dortmund, Germany (2014)
  15. Wolff, M. W.; Fortuna, A. R.; Pieler, M.; Weigel, T.; Fischer, L. M.; Reichl, U.: Upcoming chromatography media for cell culture-derived influenza virus purification. ProcessNetJahrestagung und Jahrestagung der Biotechnologen 2014 , Aachen, Germany (2014)

Poster (32)

  1. Bachmann, M.; Frensing, T.; Sandig, V.; Reichl, U.: Expression of adenoviral early-region E1A protein benefits cell culture-based influenza vaccine production. 4th International Influenza Meeting, Münster, Germany (2014)
  2. Bensmann, A.; Hanke-Rauschenbach, R.; Heyer, R.; Kohrs, F.; Benndorf, D.; Reichl, U.; Sundmacher, K.: Methanisierung von erneuerbarem Wasserstoff in Biogas-Anlagen,. ProcessNet-Anual Meeting, Aachen, Germany (2014)
  3. Cajic, S.; Müller, C.; Hennig, R.; Hoffmann, D.; Schambach, A.; Reichl, U.; Buettner, F. F.R.; Rapp, E.: The sweet beginning–N-glycosylation of induced pluripotent stem cells from a PMM2-CDG patient. 25th Joint Glycobiology Meeting, Ghent, Belgium (2014)
  4. Fernandes, P.; Castro, R.; Laske, T.; Genzel, Y.; Kremer, E.J.; Alves, P.M.; Coroadinha, A.S.: The impact of MDCK cell source on the production of Influenza and Canine Adenovirus. ECB16 - 16th European Congress on Biotechnology, Edinburgh, Scotland (2014)
  5. Fortuna, A. R.; Pieler, M.; Hundt, B.; Villain, L.; Wolff, M. W.; Reichl, U.: Membrane supports for influenza virus purification. ISPPP 2014 - 34th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Fortress Marienberg, Würzburg, Germany (2014)
  6. Fortuna, A. R.; Pieler, M.; Hundt, B.; Villain, L.; Wolff, M. W.; Reichl, U.: Membrane supports for influenza virus purification. ProcessNet-Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014, Aachen, Germany (2014)
  7. Frensing, T.; Heldt, S.; Bachmann, M.; Genzel, Y.; Jordan, I.; Reichl, U.: CONTINUOUS INFLUENZA VACCINE PRODUCTION. Vaccine Technology 2014, Playa del Carmen, Mexico (2014)
  8. Frensing, T.; Heldt, S.; Bachmann, M.; Genzel, Y.; Jordan, I.; Reichl, U.: Continuous influenza vaccine production. ProcessNet-Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014, Aachen, Germany (2014)
  9. Genzel, Y.; Tapia, F.; Vogel, T.; Vazquez-Ramirez, D.; Behrendt, I.; Jordan , I.; Sandig, V.; Hirschel, M.; Gangemi, J.D.; Reichl, U.: Disposable hollow fiber bioreactors for high cell density virus production in continuous mode. Vaccine Technology 2014, Playa del Carmen, Mexico (2014)
 
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