Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203

Contact Person

Annegret Frauendienst
Phone: +49 391 6110 200
Fax: +49 391 6110 203

Group Page

Publications

Publications BPE group

Talk (208)

  1. 2006
    Genzel, Y.; Schulze-Horsel, J.; Reichl, U.: High Cell Density Microcarrier Process in a Wave Bioreactor for the Production of Influenza A Virus. Vaccine Technology, Puerto Vallarta, Mexiko (2006)
  2. Genzel, Y.; Reichl, U.: Limits and benefits of the interpretation of extracellular metabolite data in mammalian cell culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
  3. Genzel, Y.; Kalbfuss, B.; Ritter, J. B.; Schulze-Horsel, J.; Rapp, E.; Vester, D.; Reichl, U.: Characterization and analytical issues on an influenza A virus production process. Vaccines : Quality control, scale-up and manufacture, Hamburg, Germany (2006)
  4. Genzel, Y.; Sandig, V.; Jordan, I.: Neue Zellsubstrate und Einfluss von Medien und Prozessführung in der Impfstoffproduktion. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  5. Kalbfuss, B.; Gedicke, K.; Seidel-Morgenstern, A.; Reichl, U.: Maximizing productivity in size-exclusion chromatography of influenza virus: A modelling approach. ESBES 6 : 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (2006)
  6. Kalbfuss, B.; Wolff, M. W.; Genzel, Y.; Zimmermann, A.; Best, C.; Morenweiser, R.; Reichl, U.: A generic purification scheme for the production of human influenza vaccines derived from serum-free mammalian cell culture. Vaccine Technology, Puerto Vallarta, Mexico (2006)
  7. Kalbfuss, B.; Wolff, M. W.; Genzel, Y.; Zimmermann, A.; Morenweiser, R.; Reichl, U.: Chromatography-based purification of influenza A virus for the production of human whole-virion vaccines. ISPPP 2006 : 26th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Innsbruck, Austria (2006)
  8. Kalbfuss, B.; Wolff, M. W.; Geisler, L.; Thom, V.; Reichl, U.: Konzentrierung und Aufreinigung von Influenza Viren mittels Ionenaustauscher-Membranen. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  9. Reichl, U.: Dynamics of Influenza Virus Replication in Mammalian Cell Culture. CCEX Workshop, Vancouver, Canada (2006)
  10. Reichl, U.: MDCK Cell derived Influenza Vaccines: Aspects of Modeling and Experimental Design in Upstream Processing. Meeting at Sanof Pasteur, Toronto, Canada (2006)
  11. Reichl, U.: Biological Fundamentals, Models and Technologies for Vaccine Production. Perspectives of Research - Identification and Implementation of Research Topics by Organizations : Ringberg-Symposium Mai 2006, Kreuth, Germany (2006)
  12. Reichl, U.: Mathematical Models for Mammalian Cell Growth and Virus Replication for an Influenza Vaccine Production Process. Technische Universität Berlin : Meeting, Berlin, Germany (2006)
  13. Reichl, U.: MDCK Cell Derived Influenza Vaccines: Aspects of Up- and Downstream Processing. Meeting Academy of Science, Sofia, Bulgarien (2006)
  14. Ritter, J. B.; Genzel, Y.; Reichl, U.: Monitoring Energy Metabolism: The Challenge of Intracellular Metabolite Analysis of Mammalian Cells in Culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
  15. Schulze-Horsel, J.; Bock, A.; Genzel, Y.; Reichl, U.: Mammalian cell culture for influenza vaccine production: physiology during cell growth and virus propagation phase. GVC/DECHEMA-Jahrestagungen 2006 mit 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  16. Wahl, A.; Nöh, K.; Wiechert, W.: Metabolic and Isotopic Instationary Experiments: A Simulative Study. Metabolic Engineering VI, Noordwijkerhout, The Netherlands (2006)
  17. Wahl, S. A.; Nöh, K.; Wiechert, W.: Experiments at Metabolic and Isotopic Instationary State: An Exploratory study. Metabolic Engineering VI : From recDNA Towards Engineering Biological Systems, Noordwijkerhout, Netherlands (2006)
  18. Wolff, M. W.; Kalbfuss, B.; Opitz, L.; Zimmermann, A.; Lehmann, S.; Reichl, U.: Downstream Process of Influenza Viruses. European BioPharm Scale-Up Congress 2006, Geneva, Switzerland (2006)
  19. Wolff, M. W.; Kalbfuss, B.; Lehmann, S.; Morenweiser, R.; Opitz, L.; Zimmermann, A.; Reichl, U.: Downstream Processes and Glycan Characterization of MDCK-Cell Derived Influenza Virus. BioProcess Technology - Asia, Singapore (2006)
  20. 2005
    Genzel, Y.; Schulze-Horsel, J.; Möhler, L.; Sidorenko, Y.; Reichl, U.: Influenza Vaccines: Challenges in Mammalian Cell Culture Technology. 19th ESACT Meeting, Harrogate, UK (2005)
  21. Heßeler, J.; Schmidt, J. K.; Reichl, U.; Flockerzi, D.: How to achieve coexistence in the chemostat: a combined mathematical and experimental approach. European Conference on Mathematical and Theoretical Biology (ECMTB), Dresden, Germany (2005)
  22. Wolff, M.; Kalbfuss, B.; Morenweiser, R.; Zimmermann, A.; Reichl, U.: Chromatography-based Purification of Influenza A Virus for the Production of Human Whole-Virion Vaccines. Viral Vectors and Vaccines Conference, Austin, Texas (2005)
  23. Wolff, M. W.; Salaklang, J.; Opitz, L.; Schwarzer, J.; Rapp, E.; Kalbfuss, B.; Reichl, U.: Development of a lectin-affinity chromatography step for the downstream processing of influenza virus vaccines. AICHE Annual Meeting 2005, Cincinnati, Ohio, USA (2005)
  24. 2004
    Genzel, Y.; König, S.; Reichl, U.: Amino acid analysis in mammalian cell culture based virus vaccine production processes. IICS : 17th annual International Ion Chromatography Symposium, Trier, Germany (2004)
  25. Rapp, E.; Lubda, D.; Seidel-Morgenstern, A.; Reichl, U.; Tallarek, U.: Sheathless ESI-Interface for Coupling Capillary Separation Techniques to Mass Spectromety. 37. Diskussionstagung der Deutschen Gesellschaft für Massenspektrometrie, Leipzig, Germany (2004)

Poster (281)

  1. 2017
    Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Process intensification of yellow fever virus and Zika virus production by perfusion bioreactors. 25th ESACT Meeting, Lausanne, Switzerland (2017)
  2. Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Production of yellow fever virus and Zika virus in perfusion bioreactors. DECHEMA Himmelfahrtstagung "Models for Developing and Optimising Biotech Production", Neu-Ulm, Germany (2017)
  3. 2016
    Benndorf, D.; Becher, B.; Kohrs, F.; Heyer, R.; Rapp, E.; Schlüter, A.; Sczyrba, A.: An optimized bioinformatic workflow for of biogas plants. VAAM Jahrestagung, Jena, Germany (2016)
  4. Benndorf, D.; Heyer, R.; Kohrs, F.; Schallert, K.; Muth, T.; Reichl, U.: The MetaProteomeAnalyzer software provides a complete workflow for analysis of metaproteomic data in microbiome research. International de.NBI-Symposium "Bioinformatics for Human Health & Disease", Heidelberg, Germany (2016)
  5. Benndorf, D.; Becher, B.; Kohrs, F.; Heyer, R.; Rapp, E.; Schlüter, A.; Sczyrba, A.; Reichl, U.: An optimized bioinformatic workflow for metaproteomics of biogas plants. Annual Conference of the Association for General and Applied Microbiology (VAAM), Jena, Germany (2016)
  6. Cajic, S.; Hennig, R.; Reichl, U.; Rapp, E.: Exploring the Complex World of Sialic Acids by xCGE-LIF. Frontiers in Sialic Acid Research Conference (SIAREC), Bad Lauterberg, Germany (2016)
  7. Dürr, R.; Duvigneau, S.; Laske, T.; Bachmann, M.; Kienle, A.: Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)
  8. Fischer, L.M.; Ilhan, S.; Wolff, M. W.; Reichl, U.: Purification of Influenza Virus via Continuous Chromatography. Vaccine Technology Albufeira 2016, Albufeira, Portugal (2016)
  9. Fortuna, A. R.; Teeffelen, S. v.; Taft, F.; Villain, L.; wolff, M. W.; Reichl, U.: Optimization of sulfated cellulose membrane adsorbers for the purification of influenza virus. Vaccine Technology Albufeira 2016, Albufeira, Portugal (2016)
  10. Hennig, R.; Cajic, S.; Bock, A.; Reichl, U.; Rapp, E.: Characterization of Species-Specific IgG Sialylation by xCGE-LIF. Frontiers in Sialic Acid Research Conference (SIAREC), Bad Lauterberg, Germany (2016)
  11. Heyer, R.; Kohrs, F.; Benndorf, D.; De Vrieze , J.; Rapp, E.; Schlüter, A.; Sczyrba, A.; Boon, N.: A metaproteomic approach for analysis of microbial community structure and function for improvement of biogas plant performance. Symposium on Advances and Applications in Metaproteomics, Magdeburg, Germany (2016)
  12. Laske, T.; Bachmann, M.; Frensing, T.; Reichl, U.: Model-based analysis of influenza A virus replication in genetically modified cell lines elucidates virus-host cell interactions. 17th International Conference on Systems Biology (ICSB), Barcelona, Spain (2016)
  13. Laske, T.; Heldt, F. S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. 26th Annual Meeting of the Society for Virology, Münster, Germany (2016)
  14. Marichal-Gallardo, P.; Pieler, M.; Riedel, D.; Wolff, M. W.; Reichl, U.: Chromatographic purification of cell culture-derived influenza A virus particles using cellulose filters and polyethylene glycol. International Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA) 2016 , Vienna, Austria (2016)
  15. Nikolay, A.; Castilho, L.; Tanuri, A.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static, microcarrier-based and suspension cultures using BHK and Vero cells. 1st ESACT Frontiers Retreat 2016, Lyon, France (2016)
  16. Nikolay, A.; Castilho, L.; Tanuri, A.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static, microcarrier-based and suspension cultures using BHK and Vero cells. Vaccine Technology VI, Albufeira, Portugal (2016)
  17. Nikolay, A.; Herrmann, K.; Genzel, Y.; Reichl, U.: Evaluation of producer cell lines for yellow fever virus production in up to 1 L bioreactor scale. Vaccine Technology VI, Albufeira, Portugal (2016)
  18. Pieler, M.; Frentzel, S.; Bruder, D.; Wolff, M. W.; Reichl, U.: Pseudo-affinity purification and formulation of a cell culture-derived whole influenza virus vaccine using magnetic sulfated cellulose particles. Vaccine Technology Albufeira 2016, Albufeira, Portugal (2016)
  19. Puettker, S.; Kohrs, F.; Kipping, M.; Benndorf, D.; Heyer, R.; Rapp, E.; Reichl, U.: Q-IMS-ToF versus OrbiTrap –Challenging two high resolution mass spectrometers with metaproteome samples. Metaproteomics Symposium, Magdeburg (2016)
  20. Rexer, T.; Schildbach, A.; Bergmann, C.; Klapproth, J.; Pietzsch, M.; Rapp, E.; Reichl, U.: Development of a platform for in-vitro N-glycosylation of proteins with continuous regeneration of GDP-Mannose by a cascade of isolated enzymes. DECHEMA Himmelfahrtstagung 2016, Koblenz, Germany (2016)
  21. Rexer, T.; Rapp, E.; Reichl, U.; Bergmann, C.; Schildbach, A.; Pietzsch, M.: Development of a Platform for in vitro N-Glycosylation of Therapeutic Proteins by a Cascade of Isolated Enzymes. GlycoT2016: The 10th International Symposium on Glycosyltransferases, Toronto, Canada (2016)
  22. Rodrigues Correia Ramos, J.; Rath, A.; Genzel, Y.; Rose, T.; Sandig, V.; Reichl, U.: A Dynamic Model of Growth and Metabolism of AGE1.HN Suspension Cells. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)
  23. Rüdiger, D.; Heldt, S.; Kupke, S. Y.; Reichl, U.: Stochastic multiscale modeling of influenza virus production in cell cultures. Poster presented at 6th IFAC Conference on Foundations of Systems Biology in Engineering. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)
  24. Taft, F.; Van Teeffelen, S.; Wolff, M.; Fortuna, A.; Reichl, U.; Villain, L.: Influenza virus capture using membrane chromatography: improving selectivity by matrix design and pseudo-affinity ligand interactions. Prep Symposium 2016, Philadelphia, USA (2016)
  25. Vazquez-Ramirez, D.; Nikolay, A.; Genzel, Y.; Reichl, U.: On-line monitoring tools in batch and (semi-)perfusion cultivations for vaccine production. 4th BioProScale Symposium "Bioprocess intensification through Process Analytical Technology (PAT) and Quality by Design (QbD)", Berlin (2016)
 
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