Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203

Contact Person

Annegret Frauendienst
Phone: +49 391 6110 200
Fax: +49 391 6110 203

Group Page

Publications

Publications BPE group

Talk (210)

  1. 2007
    Reichl, U.: Mathematical Modeling of Mammalian Cell Cultures - Cell Growth and Product Synthesis. MPG-CNRS Treffen, Paris, France (2007)
  2. Reichl, U.: MDCK cell derived influenza vaccines - aspects of up- and downstream processing. Meeting Merck & Co., Inc., USA (2007)
  3. Reichl, U.: Mathematical Modeling of Mammalian Cell Cultures: From Cell Populations to Individual Cells. Workshop "Systems biology", Leipzig, Germany (2007)
  4. Reichl, U.: A Systems Perspective of Virus Replication in Mammalian Cell Cultures. Meeting at MPI Golm, Potsdam-Golm, Germany (2007)
  5. Reichl, U.: Influenza Vaccines: Challenges in Optimization of Virus Yields in Mammalian Cell Culture. Vaccine Congress, Amsterdam, The Netherlands (2007)
  6. Reichl, U.: Characterization of Cell Growth and Influenza Virus Replication in Microcarrier Culture. Kooperationsgespräch bei ROCHE AG, Penzberg, Germany (2007)
  7. Reichl, U.: A Systems Perspective of Influenza Virus Replication in Cell Cultures. European Conference on Complex Systems, Dresden, Germany (2007)
  8. Ritter, J. B.; Genzel, Y.; Reichl, U.: Metabolite Analysis in Mammalian Cells: How to generate reliable data sets? 20th ESACT meeting, Dresden, Germany (2007)
  9. Schmidt, J. K.; Riedele, C.; Regestein, L.; Geisler, L.; Reichl, U.: A Medically Relevant Three-Species Mixed Culture in a Chemostat: Mathematical Modelling and Experiments to Study Interaction Effects. European BioPerspectives 2007, Cologne, Germany (2007)
  10. Schwarzer, J.; Rapp, E.; Reichl, U.: N-glycan analysis method for cell culture derived influenza virus hemagglutinin. Joint Meeting 2007, Lille, France (2007)
  11. 2006
    Genzel, Y.; Reichl, U.: Production of vaccines based on animal cell technology. Production of Biopharmaceuticals in Animal Cell Cultures, Rio de Janeiro, Brazil (2006)
  12. Genzel, Y.; Schulze-Horsel, J.; Reichl, U.: High Cell Density Microcarrier Process in a Wave Bioreactor for the Production of Influenza A Virus. Vaccine Technology, Puerto Vallarta, Mexiko (2006)
  13. Genzel, Y.; Reichl, U.: Limits and benefits of the interpretation of extracellular metabolite data in mammalian cell culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
  14. Genzel, Y.; Kalbfuss, B.; Ritter, J. B.; Schulze-Horsel, J.; Rapp, E.; Vester, D.; Reichl, U.: Characterization and analytical issues on an influenza A virus production process. Vaccines : Quality control, scale-up and manufacture, Hamburg, Germany (2006)
  15. Genzel, Y.; Sandig, V.; Jordan, I.: Neue Zellsubstrate und Einfluss von Medien und Prozessführung in der Impfstoffproduktion. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  16. Kalbfuss, B.; Gedicke, K.; Seidel-Morgenstern, A.; Reichl, U.: Maximizing productivity in size-exclusion chromatography of influenza virus: A modelling approach. ESBES 6 : 6th European Symposium on Biochemical Engineering Science, Salzburg, Austria (2006)
  17. Kalbfuss, B.; Wolff, M. W.; Genzel, Y.; Zimmermann, A.; Best, C.; Morenweiser, R.; Reichl, U.: A generic purification scheme for the production of human influenza vaccines derived from serum-free mammalian cell culture. Vaccine Technology, Puerto Vallarta, Mexico (2006)
  18. Kalbfuss, B.; Wolff, M. W.; Genzel, Y.; Zimmermann, A.; Morenweiser, R.; Reichl, U.: Chromatography-based purification of influenza A virus for the production of human whole-virion vaccines. ISPPP 2006 : 26th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Innsbruck, Austria (2006)
  19. Kalbfuss, B.; Wolff, M. W.; Geisler, L.; Thom, V.; Reichl, U.: Konzentrierung und Aufreinigung von Influenza Viren mittels Ionenaustauscher-Membranen. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  20. Reichl, U.: Dynamics of Influenza Virus Replication in Mammalian Cell Culture. CCEX Workshop, Vancouver, Canada (2006)
  21. Reichl, U.: MDCK Cell derived Influenza Vaccines: Aspects of Modeling and Experimental Design in Upstream Processing. Meeting at Sanof Pasteur, Toronto, Canada (2006)
  22. Reichl, U.: Biological Fundamentals, Models and Technologies for Vaccine Production. Perspectives of Research - Identification and Implementation of Research Topics by Organizations : Ringberg-Symposium Mai 2006, Kreuth, Germany (2006)
  23. Reichl, U.: Mathematical Models for Mammalian Cell Growth and Virus Replication for an Influenza Vaccine Production Process. Technische Universität Berlin : Meeting, Berlin, Germany (2006)
  24. Reichl, U.: MDCK Cell Derived Influenza Vaccines: Aspects of Up- and Downstream Processing. Meeting Academy of Science, Sofia, Bulgarien (2006)
  25. Ritter, J. B.; Genzel, Y.; Reichl, U.: Monitoring Energy Metabolism: The Challenge of Intracellular Metabolite Analysis of Mammalian Cells in Culture. 1st Max Planck Workshop on "Metabolomics", Magdeburg, Germany (2006)
  26. Schulze-Horsel, J.; Bock, A.; Genzel, Y.; Reichl, U.: Mammalian cell culture for influenza vaccine production: physiology during cell growth and virus propagation phase. GVC/DECHEMA-Jahrestagungen 2006 mit 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Germany (2006)
  27. Wahl, A.; Nöh, K.; Wiechert, W.: Metabolic and Isotopic Instationary Experiments: A Simulative Study. Metabolic Engineering VI, Noordwijkerhout, The Netherlands (2006)
  28. Wahl, S. A.; Nöh, K.; Wiechert, W.: Experiments at Metabolic and Isotopic Instationary State: An Exploratory study. Metabolic Engineering VI : From recDNA Towards Engineering Biological Systems, Noordwijkerhout, Netherlands (2006)
  29. Wolff, M. W.; Kalbfuss, B.; Opitz, L.; Zimmermann, A.; Lehmann, S.; Reichl, U.: Downstream Process of Influenza Viruses. European BioPharm Scale-Up Congress 2006, Geneva, Switzerland (2006)
  30. Wolff, M. W.; Kalbfuss, B.; Lehmann, S.; Morenweiser, R.; Opitz, L.; Zimmermann, A.; Reichl, U.: Downstream Processes and Glycan Characterization of MDCK-Cell Derived Influenza Virus. BioProcess Technology - Asia, Singapore (2006)
  31. 2005
    Genzel, Y.; Schulze-Horsel, J.; Möhler, L.; Sidorenko, Y.; Reichl, U.: Influenza Vaccines: Challenges in Mammalian Cell Culture Technology. 19th ESACT Meeting, Harrogate, UK (2005)
  32. Heßeler, J.; Schmidt, J. K.; Reichl, U.; Flockerzi, D.: How to achieve coexistence in the chemostat: a combined mathematical and experimental approach. European Conference on Mathematical and Theoretical Biology (ECMTB), Dresden, Germany (2005)
  33. Wolff, M.; Kalbfuss, B.; Morenweiser, R.; Zimmermann, A.; Reichl, U.: Chromatography-based Purification of Influenza A Virus for the Production of Human Whole-Virion Vaccines. Viral Vectors and Vaccines Conference, Austin, Texas (2005)
  34. Wolff, M. W.; Salaklang, J.; Opitz, L.; Schwarzer, J.; Rapp, E.; Kalbfuss, B.; Reichl, U.: Development of a lectin-affinity chromatography step for the downstream processing of influenza virus vaccines. AICHE Annual Meeting 2005, Cincinnati, Ohio, USA (2005)
  35. 2004
    Genzel, Y.; König, S.; Reichl, U.: Amino acid analysis in mammalian cell culture based virus vaccine production processes. IICS : 17th annual International Ion Chromatography Symposium, Trier, Germany (2004)
  36. Rapp, E.; Lubda, D.; Seidel-Morgenstern, A.; Reichl, U.; Tallarek, U.: Sheathless ESI-Interface for Coupling Capillary Separation Techniques to Mass Spectromety. 37. Diskussionstagung der Deutschen Gesellschaft für Massenspektrometrie, Leipzig, Germany (2004)

Poster (287)

  1. 2017
    Bergmann, C.; Schildbach, A.; Rexer, T.; Rapp, E.; Reichl, U.; Pietzsch, M.: In-vitro synthesis of a phytanyl-pyrophosphate-linked oligosaccharide by a cascade of Alg2 and Alg11 as part of a platform for N-glycosylation of therapeutic proteins. GlycoBioTec Symposium 2017, Berlin, Germany (2017)
  2. Kohrs, F.; Heyer, R.; Bissinger, T.; Kottler, R.; Schallert, K.; Püttker, S.; Behne, A.; Rapp, E.; Benndorf, D.; Reichl, U.: Proteotyping of microbial communities from laboratory-scale biogas plants reveals multiple steady-states. 14th Symposium on Bacterial Genetics and Ecology (BAGECO 14), Aberdeen, Scotland (2017)
  3. Mahour, R.; Klapproth, J.; Rexer, T.; Schildbach, A.; Pietzsch, M.; Rapp, E.; Reichl, U.: In vitro multienzymatic network for production of UDP-GlcNAc. DECHEMA Summer School 2017: Biotransformations 2017, Hannover, Germany (2017)
  4. Mahour, R.; Klapproth, J.; Rexer, T.; Schildbach, A.; Pietzsch, M.; Rapp, E.; Reichl, U.: In vitro multienzymatic network for production of UDP-GlcNAc. GlycoBioTec Symposium 2017, Berlin, Germany (2017)
  5. Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Process intensification of yellow fever virus and Zika virus production by perfusion bioreactors. 25th ESACT Meeting, Lausanne, Switzerland (2017)
  6. Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Production of yellow fever virus and Zika virus in perfusion bioreactors. DECHEMA Himmelfahrtstagung "Models for Developing and Optimising Biotech Production", Neu-Ulm, Germany (2017)
  7. Pralow, A.; Nguyen-Khuong, T.; Pioch, M.; Hennig, R.; Hoffmann, M.; Rapp, E.; Reichl, U.: Comprehensive structural and site-specific N-glycan analysis of influenza A/PR8/34 virus propagated in adherent and suspension MDCK cells. GlycoBioTec Symposium 2017, Berlin, Germany (2017)
  8. Rexer, T.; Schildbach, A.; Rapp, E.; Reichl, U.; Pietzsch, M.: In-vitro synthesis of phytanyl-pyrophosphate-linked oligosaccharides by cascades of glycosyltransferases as basic platform for N-glycosylation of therapeutic proteins. DECHEMA Summer School 2017: Biotransformations 2017, Hannover, Germany (2017)
  9. 2016
    Benndorf, D.; Becher, B.; Kohrs, F.; Heyer, R.; Rapp, E.; Schlüter, A.; Sczyrba, A.: An optimized bioinformatic workflow for of biogas plants. VAAM Jahrestagung, Jena, Germany (2016)
  10. Benndorf, D.; Heyer, R.; Kohrs, F.; Schallert, K.; Muth, T.; Reichl, U.: The MetaProteomeAnalyzer software provides a complete workflow for analysis of metaproteomic data in microbiome research. International de.NBI-Symposium "Bioinformatics for Human Health & Disease", Heidelberg, Germany (2016)
  11. Benndorf, D.; Becher, B.; Kohrs, F.; Heyer, R.; Rapp, E.; Schlüter, A.; Sczyrba, A.; Reichl, U.: An optimized bioinformatic workflow for metaproteomics of biogas plants. Annual Conference of the Association for General and Applied Microbiology (VAAM), Jena, Germany (2016)
  12. Cajic, S.; Hennig, R.; Reichl, U.; Rapp, E.: Exploring the Complex World of Sialic Acids by xCGE-LIF. Frontiers in Sialic Acid Research Conference (SIAREC), Bad Lauterberg, Germany (2016)
  13. Dürr, R.; Duvigneau, S.; Laske, T.; Bachmann, M.; Kienle, A.: Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)
  14. Fischer, L.M.; Ilhan, S.; Wolff, M. W.; Reichl, U.: Purification of Influenza Virus via Continuous Chromatography. Vaccine Technology Albufeira 2016, Albufeira, Portugal (2016)
 
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